@article {Searlseg6, author = {Searls, David B.}, title = {Omic Empiricism}, volume = {2}, number = {68}, pages = {eg6--eg6}, year = {2009}, doi = {10.1126/scisignal.268eg6}, publisher = {Science Signaling}, abstract = {The rise of omics signals a shift from hypothesis-driven to data-driven, {\textquotedblleft}bottom-up{\textquotedblright} research, whereas systems biology stresses modeling and claims to move beyond reductionism. These trends are at opposite poles of a long-standing duality between empiricism and rationalism. Twenty-first-century biology might benefit from a consideration of how philosophers have approached and attempted to reconcile this duality.}, issn = {1945-0877}, URL = {https://stke.sciencemag.org/content/2/68/eg6}, eprint = {https://stke.sciencemag.org/content/2/68/eg6.full.pdf}, journal = {Science Signaling} }