APA Report 1.0 Standard Panel

This ELISA assay detects the presence of auto-antibodies against an extensive list of phospholipid headgroups and isotypes. The standard panel was designed to include the phospholipid antibodies commonly considered to be within the standard of care guidelines from ACOG.[1]

Antiphospholipid (aPL) antibodies recognize negatively charged phospholipids in the presence of protein cofactors such as β2glycoprotein I (β2GPI) or proteins alone (e.g. β2GPI), and are associated with thrombosis and pregnancy losses and any pregnancy morbidities. Target cells and tissues include: decidual cells, trophoblasts, and placenta. The APA Report 1.0 Standard Panel includes the following phospholipid headgroups and coagulation cofactors:

  • Cardiolipin (IgG, IgM, IgA)
  • Beta2Glycoprotein 1 (IgG, IgM, IgA)
  • APhL® (IgG, IgM)

Test Specifications:
