@article {886, title = {Modulation of untruthful responses with non-invasive brain stimulation.}, journal = {Front Psychiatry}, volume = {3}, year = {2012}, month = {2012}, pages = {97}, abstract = {

Deceptive abilities have long been studied in relation to personality traits. More recently, studies explored the neural substrates associated with deceptive skills suggesting a critical role of the prefrontal cortex. Here we investigated whether non-invasive brain stimulation over the dorsolateral prefrontal cortex (DLPFC) could modulate generation of untruthful responses about subject{\textquoteright}s personal life across contexts (i.e., deceiving on guilt-free questions on daily activities; generating previously memorized lies about past experience; and producing spontaneous lies about past experience), as well as across modality responses (verbal and motor responses). Results reveal that real, but not sham, transcranial direct current stimulation (tDCS) over the DLPFC can reduce response latency for untruthful over truthful answers across contexts and modality responses. Also, contexts of lies seem to incur a different hemispheric laterality. These findings add up to previous studies demonstrating that it is possible to modulate some processes involved in generation of untruthful answers by applying non-invasive brain stimulation over the DLPFC and extend these findings by showing a differential hemispheric contribution of DLPFCs according to contexts.

}, issn = {1664-0640}, doi = {10.3389/fpsyt.2012.00097}, author = {Shirley Fecteau and Boggio, Paulo and Fregni, Felipe and Pascual-Leone, Alvaro} }