MmmSC-induced recall proliferative responses of pbmc (a), and CD4+ T cells (b), collected from nonvaccinated (open circles) and vaccinated (closed circles) animals (n = 5) one month after single, double and triple vaccine inoculations.

Results represent the net effect of MmmSC stimulation (i.e., stimulated cultures minus non-stimulated cultures) and are representative of 2 independent experiments. Bars indicate median values and asterisks represent significant difference between vaccinated and naïve groups.