TY - JOUR T1 - Quantitative Comparisons of 16S rRNA Gene Sequence Libraries from Environmental Samples JF - Applied and Environmental Microbiology JO - Appl. Environ. Microbiol. SP - 4374 LP - 4376 DO - 10.1128/AEM.67.9.4374-4376.2001 VL - 67 IS - 9 AU - Singleton, David R. AU - Furlong, Michelle A. AU - Rathbun, Stephen L. AU - Whitman, William B. Y1 - 2001/09/01 UR - http://aem.asm.org/content/67/9/4374.abstract N2 - To determine the significance of differences between clonal libraries of environmental rRNA gene sequences, differences between homologous coverage curves, CX(D), and heterologous coverage curves, CXY(D), were calculated by a Cramér-von Mises-type statistic and compared by a Monte Carlo test procedure. This method successfully distinguished rRNA gene sequence libraries from soil and bioreactors and correctly failed to find differences between libraries of the same composition. ER -