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Tongkat ali's active ingredients have not been identified... but it's probably not eurycomanone

There are hundreds of specific chemicals present in tongkat ali roots. They mostly belong to the following classes of chemicals:








The most prevalent ingredient of tongkat ali root, of course, is cellulose (fiber).

Of the more complicated chemicals, two are fairly easy two detect:

eurycomanone and eyrycomanol

Both are quassinoids.

Because eurycomanone is typical for tongkat ali and because it can be detected by liquid chromatography, it has been suggested that eurycomanone is used as a marker chemical.

This means that if an unknown substance is run through a liquid chromatograph, and the absorption pattern of eurycomanone shows on the filter paper, then one can assume that the unknown compound is tongkat ali, or contains tongkat ali.

This has nothing to do with an analysis of what causes the testosterone and libido boosting effects if tongkat ali.

A marker is a chemical that IDENTIFIES a substance. This is different from EFFICACY, the effect-causing chemical.

The effects of tongkat ali and tongkat ali extract may be caused by alkaloids or steroids, or any yet unresearched or undiscovered chemical constituents of tongkat ali root. If you have a faible for chemistry, you can see a yet uncompleted list of chemical constituents of tongkat ali roots below.

One thing is sure: any claim of standardization to certain levels of eurycomanone is cheap propaganda, not science.

If you consider buying tongkat ali, don't be so gullible. Buy something with government approval. That gives you at least some protection.

Here, for those chemically inclined, an expanded list of the not-yet mentioned chemical constituents of tongkat ali. Any of them may be responsible for the desired effects. Most likely, several compounds work in unison.

Squalene-type triterpenes:


14-deacetyl eurylene longilene peroxide


n-pentyl â-carboline- 1-propionate

1-hydroxy-9-methoxycanthin-6-one 5-hydroxymethyl-9-methoxycanthin-6-one

19 known ß-caroline alkaloids

3 ß-caroline lkaloids


1-hydroxy- 9-methoxycanthin-6-one

Two biphenylneoligans:



Another 27 quassinoids:

eurycolactone D, E, F

eurycomanone-type C20 and C19

one klaineanone-type C20 

six eurycomalactone-type C19 quassinoids

An epoxy group type of eurycomalactone


13a, 21-epoxyeurycomanone eurylactone


Furthermore, for comprehensiveness, there are also 83 volatile compounds, including:



4-ethynyl-4-hydroxy-3 5, 5-trimethyl-2-cyclohex-1-enone

benzoic acid

acetic acid

octanoic acid

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Abubakar, B.M., Salleh, F.M., Wagiran, A. (2017) Chemical Composition of Eurycoma longifolia (Tongkat Ali) and the Quality Control of its Herbal Medicinal Products. Journal of Applied Sciences, Volume 17 Issue 7, Pages: 324-338 Tongkatali.org Bibliography8


George, A., Kawasaki, Y., Abas, A., (2017) Eurycoma longifolia and its use in entrancing stimulating immune system. Google Patents Retrieved from: Tongkatali.org Bibliography


Mohamed, A.N., Vejayan, J., Mohd Yusoff, M. (2015) Review on eurycoma longifolia pharmacological and phytochemical properties Journal of Applied Sciences, Volume 15, Issue 6, Pages: 831-844 Tongkatali.org Bibliography

Vejayan, J., Mohamed, A.N., Zulkifli, A.A., Che Yahya, Y.A. (2018) Marker to authenticate Eurycomalongifolia containing aphrodisiac herbal products. Current science Volume 115 Issue 5 Page: 886 Retrieved from research.net Marker to authenticate Eurycoma longifolia (Tongkat Ali) containing aphrodisiac herbal products

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