%A Fan,Ying %A Gao,Rui-Han %A Huang,Ying %A Bian,Bing %A Tao,Zhu %A Xiao,Xin %D 2019 %J Frontiers in Chemistry %C %F %G English %K Twisted cucurbit[14]uril,thioflavin T,Fluorescent probe,Triazole fungicides,Flusilazole %Q %R 10.3389/fchem.2019.00154 %W %L %N 154 %M %P %7 %8 2019-March-21 %9 Original Research %# %! ThT@tQ[14] fluorescent probe %* %< %T Supramolecular Fluorescence Probe Based on Twisted Cucurbit[14]uril for Sensing Fungicide Flusilazole %U https://www.frontiersin.org/article/10.3389/fchem.2019.00154 %V 7 %0 JOURNAL ARTICLE %@ 2296-2646 %X The host-guest complex of the common dye, thioflavin T (ThT), and twisted cucurbit[14]uril (tQ[14]) was selected as a fluorescent probe to determine non-fluorescent triazole fungicides, including flusilazole, azaconazole, triadimefon, tebuconazole, tricyclazole, flutriafol, penconazole, and triadimenol isomer A, in an aqueous solution. The experimental results reveal that the ThT@tQ[14] probe selectively responded to flusilazole with significant fluorescence quenching and a detection limit of 1.27 × 10−8 mol/L. In addition, the response mechanism involves not only a cooperation interaction—ThT occupies a side-cavity of the tQ[14] host and the triazole fungicide occupies another side-cavity of the tQ[14] host—but also a competition interaction in which both ThT and the triazole fungicide occupy the side-cavities of the tQ[14] host.