1tph Summary



The structure was published by Zhang, Z., Sugio, S., Komives, E.A., et al., Knowles, J.R., Petsko, G.A., and Ringe, D., in 1994 in a paper entitled "Crystal structure of recombinant chicken triosephosphate isomerase-phosphoglycolohydroxamate complex at 1.8-A resolution." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.8 Å and deposited in 1993.


This PDB entry contains multiple copies of the structure of TRIOSEPHOSPHATE ISOMERASE.


The molecule most likely forms homodimers.


1 TRIOSEPHOSPHATE ISOMERASE P00940 (2-248) (TPIS_CHICK)search Gallus gallussearch 100% 247 99%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P00940 (2 - 248) TRIOSEPHOSPHATE ISOMERASE Gallus gallus

1, 2 (P00940) Triosephosphate isomerase (TIM)search Aldolase class Isearch PF00121: Triosephosphate isomerasesearch

1, 2 (P00940) glycolysissearch metabolic processsearch carbohydrate metabolic processsearch glyceraldehyde-3-phosphate metabolic processsearch gluconeogenesissearch small molecule metabolic processsearch pentose-phosphate shuntsearch triose-phosphate isomerase activitysearch catalytic activitysearch isomerase activitysearch cytosolsearch

Chain InterPro annotation
1, 2 Triosephosphate isomerasesearch Aldolase-type TIM barrelsearch Triosephosphate isomerase, active sitesearch Triosephosphate isomerase, bacterial/eukaryoticsearch