My Memory is a Hazy Fog. How About Yours?

| Sun Feb. 19, 2012 11:54 PM EST


What does PKMzeta do? The molecule’s crucial trick is that it increases the density of a particular type of sensor called an AMPA receptor on the outside of a neuron....This process requires constant upkeep—every long-term memory is always on the verge of vanishing. As a result, even a brief interruption of PKMzeta activity can dismantle the function of a steadfast circuit.


My memory has always been terrible. My mother is nearly 80 and still remembers classmates from her kindergarten days. I barely even remember going to kindergarten. Actually, that's too charitable: I don't remember going to kindergarten. Or first grade. Or fifth grade. Or high school. Or college. Or, for that matter, stuff I did two years ago.

Is this an exaggeration? Only barely. I remember occasional shreds from years past, but that's about it. On the bright side, this means that if I had a nasty fight with you a few years ago, there's a good chance I have no memory of it. On the not-so-bright side, it means that if we were close friends in high school, I might or might not even remember knowing you, let alone remember anything substantive about what we did together.
