, Volume 89, Issue 2, pp 273-275

Surface-enhanced Raman scattering of λ -DNA

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By using the molecular combing method, we stretched DNA molecules with colloidal silver nanoparticles adsorbed on them. Surface-enhanced Raman scattering (SERS) spectra were recorded in this particular DNA/Ag system. We also studied SERS spectra of DNA molecules in solution. The spectra of DNA in different concentration solution show distinct differences, and we speculate that the coiling states of DNA molecules are different in different concentrations, leading to the spectral differences.


33.20.Fb; 42.62.Fi; 78.67.-n; 73.20.Mf; 87.64.-t