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Mitochondrial inheritance

A mode of inheritance that is observed for traits related to a gene encoded on the mitochondrial genome. Because the mitochondrial genome is essentially always maternally inherited, a mitochondrial condition can only be transmitted by females, although the condition can affect both sexes. The proportion of mutant mitochondria can vary (heteroplasmy). [from HPO]

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Warburg Effect

This effect refers to the high cellular levels of lactic acid in tumor cells, and is named after Otto Warburg who worked on photosynthesis. Tumor cells use excessive glucose in their rapid growth, and lactic acid is a product of the glycolytic pathway. This process is not inhibited by oxygen, therefore, it is also called aerobic glycolysis. [from NCI]

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Cell or Molecular Dysfunction

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