TY - JOUR T1 - GAstroesophageal reflux to the proximal esophagus in infants with bronchopulmonary dysplasia AU - Sindel BD AU - Maisels M AU - Ballantine TN Y1 - 1989/09/01 N1 - 10.1001/archpedi.1989.02150210139034 JO - American Journal of Diseases of Children SP - 1103 EP - 1106 VL - 143 IS - 9 N2 - • Recurrent aspiration after gastroesophageal reflux (GER) may contribute to the severity of chronic lung disease. If so, it should be possible to document acid reflux to the proximal esophagus. Using an esophageal pH probe placed at the level of the first or second thoracic vertebra, we evaluated GER in 14 infants with bronchopulmonary dysplasia (BPD) and 13 infants without BPD. The infants with BPD had significantly less GER, as measured by the percentage of time the pH was less than 4 (3.26% ± 7.05% vs 12.88% ± 15.27% [mean±SD]), number of GER episodes per hour (0.46±0.66 vs 1.35±0.83), number of GER episodes lasting longer than 5 minutes per hour (0.10±0.23 vs 0.31 ±0.29), and longest GER episode (6.76±10.29 vs 26.66±38.30 minutes). Gastroesophageal reflux may be unimportant in infants with BPD, or even occasional episodes of GER may aggravate existing lung disease.(AJDC. 1989;143:1103-1106) SN - 0002-922X M3 - doi: 10.1001/archpedi.1989.02150210139034 UR - http://dx.doi.org/10.1001/archpedi.1989.02150210139034 ER -