Molecularly imprinted polymer particles: Formation, characterization and application.


Shahar T, Tal N, Mandler D. Molecularly imprinted polymer particles: Formation, characterization and application. Colloids Surf., AColloids and Surfaces, A: Physicochemical and Engineering Aspects. 2016;495 :11 - 19.

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Molecularly imprinted polymer (MIP) particles offer many advantages as recognition objects. Therefore, we examd. thoroughly the effect of various exptl. parameters including cross-linker concn., nature of solvent, type of template and its concn., reaction vol. and temp. on the formation of particulate MIPs using pptn. polymn. The particles were characterized by various methods, such as XHR-SEM, HR-TEM and BET. Statistical calcns. were carried out using ImageJ software over population of at least 200 particles in each expt. The reproducibility of MIP synthesis was examd. and the SD was better than 10%. MIP particles were imprinted with different Sudan dye derivs. (Sudan II, III, IV and Sudan orange G). Raman and FTIR spectroscopies were used to prove the successful imprinting. Reuptake measurements were carefully compared between non-imprinted molecularly polymer (NIP) and MIP particles employing the same quantity and similar diam. and polydispersity of NIP and MIP, as never reported before. The results showed that MIP particles imprinted by Sudan IV showed higher selectivity toward this specific dye as compared with MIPs imprinted by other Sudan dyes and NIPs. [on SciFinder(R)]


CAPLUS AN 2016:222036(Journal; Online Computer File)