TY - JOUR T1 - HYperbaric oxygen therapy in chronic hemorrhagic shock AU - Amonic RS AU - Cockett AK AU - Lorhan PH AU - Thompson JC Y1 - 1969/06/16 N1 - 10.1001/jama.1969.03160110023005 JO - JAMA SP - 2051 EP - 2054 VL - 208 IS - 11 N2 - A Jehovah's Witness patient bled massively per rectum, but refused blood transfusion. A bleeding gastric leiomyoma was excised at eventual operation. His hemoglobin value fell to 2.2 gm/100 cc and on the third postoperative day he showed evidence of severe cerebral and myocardial ischemia and congestive heart failure developed. Hyperbaric oxygen therapy caused a reversal of all signs and symptoms of hypoxia, and the patient recovered. Blood taken from a subject breathing air at 1 atmosphere pressure has 0.3 vol% of oxygen dissolved in plasma; if the subject breathes 100% oxygen at 2 atmospheres absolute pressure, the amount of oxygen in physical solution in plasma is 4 vol%. In a patient with greatly diminished hemoglobin value, this increase in plasma oxygen may be adequate to sustain life. SN - 0098-7484 M3 - doi: 10.1001/jama.1969.03160110023005 UR - http://dx.doi.org/10.1001/jama.1969.03160110023005 ER -