SGD Paper Help

Schwalb B, et al.  (2012) Measurement of genome-wide RNA synthesis and decay rates with Dynamic Transcriptome Analysis (DTA). Bioinformatics 28(6):884-5

Abstract: Standard transcriptomics measures total cellular RNA levels. Our understanding of gene regulation would be greatly improved if we could measure RNA synthesis and decay rates on a genome-wide level. To that end, the Dynamic Transcriptome Analysis (DTA) method has been developed. DTA combines metabolic RNA labeling with standard transcriptomics to measure RNA synthesis and decay rates in a precise and non-perturbing manner. Here, we present the open source R/Bioconductor software package DTA. It implements all required bioinformatics steps that allow the accurate absolute quantification and comparison of RNA turnover.


Topics addressed in this paper

Topics Topics not linked to Genes Genes
Alias blue ball
Computational analysis yg ball
Mutants/Phenotypes blue ball
Omics yg ball
Primary Literature blue ball
Protein Sequence Features blue ball

Author Searches

  1. (1) Choose an author,
  2. (2) Choose a search parameter,
  3. (3) Click to implement