, Volume 35, Issue 5, pp 685–686 | Cite as

Inhibitory effect of cytokinins on PHA-induced human lymphocyte stimulation

  • T. Saito
  • Y. Shibata
  • T. Kurokawa
  • N. Ishida


The inhibitory effect of various purine derivatives on PHA-induced human lymphocyte blast formation was studied. Two nucleoside cytokinins, N6-benzyladenosine and N6-isopentenyladenosine, inhibited blast formation at concentrations as low as 10−6 M. However, the other cytokinins, which lacked the ribosyl residue at N9 position, had to be at the higher molar concentration of 10−4 before they could induce the same inhibitory effect.


Purine Nucleoside Molar Concentration Human Lymphocyte High Molar Concentration 


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Copyright information

© Birkhäuser Verlag 1979

Authors and Affiliations

  • T. Saito
    • 1
  • Y. Shibata
    • 1
  • T. Kurokawa
    • 1
  • N. Ishida
    • 1
  1. 1.Department of BacteriologyTohoku University School of MedicineSendai(Japan)

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