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Welding, Molybdenum Trioxide, and Indium Tin Oxide
IARC Monographs on the Evaluation of Carcinogenic Risks to Humans Volume 118 This volume of the IARC Monographs provides evaluations of the carcinogenicity of welding and welding fumes, molybdenum trioxide, and indium tin oxide. Worldwide, an estimated 11 million workers have a job title of welder, and around 110 million additional workers probably incur welding-related exposures. Welding can involve exposures to fumes, gases, ultraviolet radiation and electromagnetic fields, and co-exposures to asbestos and solvents. The extent and type of exposure can depend on the process used, the material...
Parkinson’s disease and occupational exposures
A systematic literature review and meta-analyses Objectives: We conducted a systematic literature review to identify studies fulfilling good scientific epidemiological standards for use in meta-analyses of relevant risk factors for Parkinson's disease. Methods: Our search identified 103 original publications on associations between work and Parkinson's disease. GRADE guidelines were used to ensure high scientific quality, and reliable guidelines were applied to classify the papers. Of the 103 articles, 47 fulfilled good scientific standards while 56 were methodologically deficient and thus...
Rhinite et asthme en relation avec les activités de soudage et de brasage
Les différents procédés de soudage et techniques connexes ont la particularité de générer des fumées dont la composition et l'intensité d'émission varient selon la technique employée et la nature des métaux travaillés. Si le caractère irritant des fumées de soudage peut en lui-même induire ou aggraver une rhinite ou un asthme, certains de leurs constituants peuvent également être impliqués dans l'apparition de rhinite et d'asthme par l'intermédiaire...
Single and Combined Exposure to Zinc- and Copper-Containing Welding Fumes Lead to Asymptomatic Systemic Inflammation
Objective: Recently, it has been shown that exposure to welding fumes containing both zinc and copper leads to asymptomatic systemic inflammation in humans as shown by an increase of blood C-reactive protein. In the present study, it was investigated which metal is responsible for this effect. Methods: Fifteen healthy male subjects were exposed under controlled conditions to welding fumes containing either zinc, or copper, or copper and zinc. Results: For each exposure blood C-reactive protein increased. Conclusions: Copper- and zinc-containing welding fumes are able to induce systemic inflammation...
Assessment of the Biological Effects of Welding Fumes Emitted From Metal Active Gas and Manual Metal Arc Welding in Humans
Objective: Emissions from a particular welding process, metal inert gas brazing of zinc-coated steel, induce an increase in C-reactive protein. In this study, it was investigated whether inflammatory effects could also be observed for other welding procedures. Methods: Twelve male subjects were separately exposed to (1) manual metal arc welding fumes, (2) filtered air, and (3) metal active gas welding fumes for 6 hours. Inflammatory markers were measured in serum before, and directly, 1 and 7 days after exposure. Results: Although C-reactive protein concentrations remained unchanged, neutrophil...

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