@article { editor = {,}, title = {CRISPR Meets CAR T-cell Therapy}, year = {2017}, doi = {10.1158/2159-8290.CD-NB2017-040}, publisher = {American Association for Cancer Research}, abstract = {Using CRISPR/Cas9 technology, researchers have devised a method to deliver a CAR gene to a specific locus, TRAC, in T cells. This targeted approach yielded therapeutic cells that were more potent even at low doses; in a mouse model of acute lymphoblastic leukemia, they outperformed CAR T cells created with a randomly integrating retroviral vector.}, issn = {2159-8274}, URL = {https://cancerdiscovery.aacrjournals.org/content/early/2017/03/21/2159-8290.CD-NB2017-040}, eprint = {https://cancerdiscovery.aacrjournals.org/content}, journal = {Cancer Discovery} }