Sensitivity, specificity, predictive values and likelihood ratios of models according to optimal cut-off for predicting HBsAg seroclearance.

PPV, positive predictive value. NPV, negative predictive value. LR+, positive likelihood ratio. LR−, negative likelihood ratio. ANN, artificial neural network. LRM, logistic regression model. qHBsAg, 3 years before baseline; HBV DNA, 3 years before baseline.