The domain within your query sequence starts at position 6 and ends at position 122; the E-value for the Transglut_N domain shown below is 3.6e-34.



PFAM accession number:PF00868
Interpro abstract (IPR001102): Synonym(s): Protein-glutamine gamma-glutamyltransferase, Fibrinoligase, TGase


Transglutaminases are widely distributed in various organs, tissues and body fluids. The best known transglutaminase is blood coagulation factor XIII, a plasma tetrameric protein composed of two catalytic A subunits and two non-catalytic B subunits. Factor XIII is responsible for cross-linking fibrin chains, thus stabilising the fibrin clot.

There are commonly three domains: N-terminal, middle (IPR013808) and C-terminal (IPR008958). This entry represents the N-terminal domain found in transglutaminases.

GO process:peptide cross-linking (GO:0018149)
