Vitamins and hormones in nutrition. II. Endocrine dyscrasia

  • Benjamin F. Sieve


1. The effect of endocrine dyscrasia on vitamin absorption, and the resultant interference in the synergistic action of vitamins and hormones has been demonstrated.

2. Six representative cases, selected from a series of 200, have been discussed in detail.

3. Alleviation of symptoms, and pronounced improvement in general nutritional status was effected by substitution therapy.

4. In cases of the type herein presented, the underlying disorder is almost invariably obscure, but detailed history, careful analysis, and correlation of all data will provide the clue to diagnosis and frequently reveal the key to proper therapy.

5. Substitution therapy must be administered from the point of view of the entire endocrine picture, and should provide complete hormone replacement.


Menstrual Cycle Estrone Basal Metabolic Rate Buccal Mucous Membrane Substitution Therapy 


  1. 1.
    Sieve, B. F.: Vitamins and hormones in nutrition. Am. J. Dig. Dis., 11:179–181, June 1944.Google Scholar
  2. 2.
    Sieve, B. F.: Discussion. Allen, F. N., Clinical management of weakness and fatigue. J.A.M.A., 127:960, April 14, 1945.Google Scholar
  3. 3.
    Bucher, N. L. R. and Geschichter, C. F.: Pregnandiol and estrogen output in the urine of patients with chronic cystic mastitis. J. Clin. Endocrinology, 1:58, 1941.CrossRefGoogle Scholar
  4. 4.
    Sieve, B. F.: Discussion. Werner, A. A., The male climacteric. Report of fifty-four cases. J.A.M.A., 127:710, March 24, 1945.Google Scholar

Copyright information

© Springer-Verlag 1946

Authors and Affiliations

  • Benjamin F. Sieve
    • 1
    • 2
  1. 1.Boston City HospitalUSA
  2. 2.Tufts College Medical SchoolUSA

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