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Co-enzyme Q10 May Support Blood Pressure Regulation

Friday May 11, 2018
Co-enzyme Q10 May Support Blood Pressure Regulation

A simple supplement may benefit high blood pressure sufferers, according to a recent macro review. 

Often labelled the ‘silent killer’, hypertension (high blood pressure) affects one in four English adults (1). Uncontrolled high blood pressure is one of the largest contributors of cardiovascular disease development. Co-enzyme Q10, a vitamin-like antioxidant, has demonstrated benefits in reducing high blood pressure, thus potentially supporting cardiovascular health. 

A meta-analysis (compilation of research trials) conducted by Tabrizi tested the suggested benefits of Co-Q10 supplementation on blood pressure in hypertensive patients (2). Included in the study were 17 trials with a total of 684 participants, that were conducted in the USA, Denmark, India, Australia, and Japan. The interventions ranged from 4-24 weeks, where the dose of Co-Q10 administered varied from 100-900mg/day. 

Overall, Co-Q10 supplementation had a positive effect on blood pressure regulation. It was demonstrated that Co-Q10 significantly reduced systolic blood pressure, but had no notable effect on diastolic blood pressure. Systolic pressure is measured when your heart contracts as it pumps blood, whereas diastolic blood pressure is measured when the heart relaxes. Furthermore, it was suggested that lower doses (100-150mg/day) of Co-Q10 exerted greater benefits on blood pressure than larger doses.

Hypertension may be exasperated by oxidative damage to the arteries, causing the constriction of the vessels, thus elevating blood pressure as a result. As Co-Q10 is a potent antioxidant, it is suggested that it may lower blood pressure by preventing the constriction of blood vessels. However, further investigation of the mechanistic action of Co-Q10 is necessary to establish a clearer link.

In conclusion, extensive evidence highlights the potential efficacy of Co-Q10 supplementation on blood pressure regulation, and given the comprehensive safety data and other possible benefits of Co-Q10, it appears to be good news. However, future trials are required to further examine the effect of dietary habits on these potential results, as it was a major limitation noted by the meta-analysis.




1)      Health matters: combating high blood pressure, Public Health England, Available at:

2)      Reza Tabrizi, Maryam Akbari, Nasrin Sharifi et. al, (2018) The Effects of Coenzyme Q10 Supplementation on Blood Pressures Among Patients with Metabolic Diseases: A Systematic Review and Meta-analysis of Randomized Controlled Trials, High Blood Press Cardiovasc Prev 25:41–50




TAGS: Nutrition News and ViewsBlood Pressure


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