




Gene Review

NMD3  -  NMD3 ribosome export adaptor

Homo sapiens

Synonyms: 60S ribosomal export protein NMD3, CGI-07, hNMD3

High impact information on NMD3

  • Coordinated nuclear export of 60S ribosomal subunits and NMD3 in vertebrates [1].
  • When present in Xenopus oocytes, both wild-type and export-defective mutant hNMD3 proteins bind to newly made nuclear 60S pre-export particles at a late step of subunit maturation [1].

Anatomical context of NMD3

  • The export-defective hNMD3, but not the wild-type protein, inhibits export of 60S subunits from oocyte nuclei [1].

Associations of NMD3 with chemical compounds


  1. Coordinated nuclear export of 60S ribosomal subunits and NMD3 in vertebrates. Trotta, C.R., Lund, E., Kahan, L., Johnson, A.W., Dahlberg, J.E. EMBO J. (2003) [Pubmed]
  2. Biogenesis and nuclear export of ribosomal subunits in higher eukaryotes depend on the CRM1 export pathway. Thomas, F., Kutay, U. J. Cell. Sci. (2003) [Pubmed]
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