Sarah Berman Neurology, University of Pittsburgh, United Statesa, United Statesa,
1 protocol

Victor Van Laar Neurology, University of Pittsburgh, United States, United States,
1 protocol

Beth Arnold
  • Neurology, University of Pittsburgh, United States, United States,
  • 1 Author merit


MS, University of Pittsburgh, United States of America

Current position

Research Specialist, Neurology, PIND, United States of America


  1. Items: 14 Select item 30030401 1.
  2. Van Laar VS, Arnold B, Howlett EH, Calderon MJ, St Croix CM, Greenamyre JT, Sanders LH, Berman SB. (2018).  Evidence for Compartmentalized Axonal Mitochondrial Biogenesis: Mitochondrial DNA Replication Increases in Distal Axons As an Early Response to Parkinson's Disease-Relevant Stress. J Neurosci. 38(34):7505-7515.

  3. Van Laar VS, Roy N, Liu A, Rajprohat S, Arnold B, Dukes AA, Holbein CD, Berman SB. (2015).  Glutamate excitotoxicity in neurons triggers mitochondrial and endoplasmic reticulum accumulation of Parkin, and, in the presence of N-acetyl cysteine, mitophagy. Neurobiol Dis. 74:180-93.

  4. Van Laar VS, Arnold B, Cassady SJ, Chu CT, Burton EA, Berman SB. (2011). Bioenergetics of neurons inhibit the translocation response of Parkin following rapid mitochondrial depolarization. Hum Mol Genet. 20(5):927-40.

  5. Arnold B, Cassady SJ, VanLaar VS, Berman SB. (2011) .Integrating multiple aspects of mitochondrial dynamics in neurons: age-related differences and dynamic changes in a chronic rotenone model. Neurobiol Dis. 41(1):189-200.

  6. Berman SB, Chen YB, Qi B, McCaffery JM, Rucker EB 3rd, Goebbels S, Nave KA, Arnold BA, Jonas EA, Pineda FJ, Hardwick JM. (2009).   Bcl-x L increases mitochondrial fission, fusion, and biomass in neurons. J Cell Biol. 184(5):707-19.

  7. Premkumar DR, Arnold B, Pollack IF.  (2006).  Cooperative inhibitory effect of ZD1839 (Iressa) in combination with 17-AAG on glioma cell growth. Mol Carcinog.  45(5):288-301.

  8. Wetzel M, Premkumar DR, Arnold B, Pollack IF. (2005).  Effect of trichostatin A, a histone deacetylase inhibitor, on glioma proliferation in vitro by inducing cell cycle arrest and apoptosis. J Neurosurg. 103(6 Suppl):549-56.

  9. Premkumar DR, Arnold B, Jane EP, Pollack IF. (2006). Synergistic interaction between 17-AAG and phosphatidylinositol 3-kinase inhibition in human malignant glioma cells. Mol Carcinog. 45(1):47-59.

1 Protocol published
Primary Embryonic Rat Cortical Neuronal Culture and Chronic Rotenone Treatment in Microfluidic Culture Devices
Authors:  Victor S. Van Laar, Beth Arnold and Sarah B Berman, date: 03/20/2019, view: 433, Q&A: 0
In the study of neurodegenerative diseases, it is imperative to study the cellular and molecular changes associated with pathogenesis in the relevant cell type, central nervous system neurons. The unique compartmentalized morphology and bioenergetic ...