


(ăth'ərōsklərō`sĭs): see arteriosclerosisarteriosclerosis
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Il’inskii, B. V. Ateroskleroz. Leningrad, 1960.





References in periodicals archive ?
The current research on atherosclerosis focuses on evaluating new drug targets that have genetic and mechanistic links.
In a secondary analysis of data from the ELITE trial, Sriprasert and colleagues dug deeper to assess the impact of plasma E2 levels on progression of subclinical atherosclerosis. (2)
Repopulation of the intestinal microbiome is another novel approach to treatment of atherosclerosis that arises from this study, Spence added.
In another study in 2007 by Haghighat et al27 in mice model, supported this report and indicated that G-CSF or GM-CSF did not have any beneficial therapeutic effect on atherosclerosis.
Mechanisms of Cognitive Impairment in Nonstroke Patients With Carotid Atherosclerosis
The heart was examined grossly as well microscopically for the presence of coronary atherosclerosis and then graded for morphological type according to the American Heart Association.
However, compelling evidence demonstrated that the adventitia plays a critical role in coordinating the progression of atherosclerosis. In 1962, Schwartz and Mitchell demonstrated that the prevalence and degree of the adventitial cellular infiltration closely correlated with the severity of the atherosclerotic plaque [37].
Recently, emphasis has been placed on the role of cytokines and the way they act on a variety of objects exerting multiple effects and are largely responsible for the crosstalk among endothelial, smooth muscle cells, leukocytes, and other vascular residing cells having a potentially causative role in atherosclerosis. For example, cytokine-induced activation of ECs can induce endothelium dysfunction accompanied by upregulation of adhesion molecules and chemokines, such as intercellular adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule-1 (VCAM-1), and monocyte chemoattractant protein-1 (MCP-1), which promotes migration of immune cells (monocytes, neutrophils, and lymphocytes) into the atherosclerosis lesion [12, 13].
Results: Artesunate could attenuate the progression of atherosclerosis lesion formation alone or combined with rosuvastatin in WD fed [ApoE.sup.-/-] mice without changes in food uptake, body weight and plasma lipids level, but with a significant reduction of pro-inflammatory cytokine, such as TNF-[alpha] and IL-6.
The analysis also showed a significant relationship between the degree of fibrosis and the risk of atherosclerosis; individuals with an NAFLD fibrosis score greater than -1.455 had a 29% higher risk of subclinical carotid atherosclerosis compared to those with a score less than -1.455.
* The report provides a snapshot of the global therapeutic landscape of Atherosclerosis
This novel approach centers around the research team's previous discovery that TMAO -- trimethylamine N-oxide, a byproduct formed in the gut during digestion of animal fats -- is linked to atherosclerosis and heart disease.

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