

Dr. Jankowitz provides an overview of breast cancer risk factors, as well as factors differentiating moderate and high-risk patients. She discusses methods of preventive therapy and the benefits and risks associated with such therapy.

Educational objectives:

Upon completion of this activity, participants should be able to:

  • Estimate risk of breast cancer associated with high-risk pathologies such as ADH, ALH, Borderline DCIS, and LCIS
  • Identify the amount of risk reduction conferred to high-risk patients with preventive therapy for breast cancer
  • Describe the benefit/risk ratio of preventive therapy and its duration in patients with an elevated risk of breast cancer

Reading Resources:

  1. JCO, (2007): 25(11); 1329-1333.
  2. Coopey SB, et al. SABCS, 2011: Abs S4-4
  3. Boyd, N. J Natl Cancer Inst 2011; 103:  704-5
  4. Domchek SM, et al. JAMA 2010;304: 967-75.
  5. Fisher, B. JNCI 1998. 90(18): 1371-1388.
  6. Vogel VG; et. al. JAMA. 2006;295: 2727-2741
  7. Vogel, VG. Cancer Prev Res 2010;3:696-706
  8. Cuzick, J. Cancer Res, 2009. 69(24 Supp): pAbstract 905.
  9. Iqbal, J. Cancer Treat Rev; 2011: July 18
  10. Freedman, AN.  J Clin Oncol 2011; 29:2327-2333.
  11. Goss, PE. N Engl J Med 364; 25: 2381-2391


Dr. Jankowitz has no relevant relationships with any entities producing healthcare goods or services.

Accreditation Statement:




Release Date: 4/26/2012 | Last Modified On: 4/26/2012 | Expires: 4/25/2013

This course has been expired.