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What is Regenerative Medicine?





Dr. DuPont utilizes PRF (platelet rich fibrin) in her Chevy Chase MD practice to treat patients for a variety of conditions.





The Platelet-Rich Fibrin (PRF) technique uses the most advanced Blood Concentrate technology to generate a Fibrin Matrix rich in Platelets, Leukocytes, and Mesenchymal stem cells. This results in the constant release of growth factors and interleukins for 10-12 days that accelerate tissue healing and skin regenerating processes.

This 100% autologous (your own blood) rejuvenation technique is a substantial progress from the

well-established PRP (or Platelet-Rich Plasma) technique.


This is all natural. There is no coating, additive or anticoagulant present in the tubes, and it is proven to release a much higher concentration of growth factors for a longer period of time.


PRF (platelet-rich fibrin) is an advanced form of PRP (platelet rich plasma) that is used to improve various conditions. It is taken from a quick blood draw. Human blood contains red blood cells, white blood cells, platelets, and plasma. When blood is centrifuged (or spun in a special way), it will produce PRF. PRF has been used for decades in dentistry and orthopedics.


Dr. DuPont is now offering this technology in conjunction with her other proven treatment methods to optimize results.

PRF contains platelets, white blood cells, fibrin and stem cells.


Platelets in our blood contain proteins, or growth factors, that:

  • Increase collagen production

  • Regenerate tissue

  • Tighten skin

  • Rejuvenate the texture of the skin

  • Promote healing

  • Improve hair regrowth

White blood cells aid in tissue regeneration, and fibrin acts as a scaffolding on which the growth factors attach to allow a longer release of their growth factors. Stem cells are undifferentiated cells that can turn into specialized cells or become more stem cells. They act as a repair system for the body to replenish adult tissues.

PRF is used to address many of the same issues as PRP, but PRF releases growth factors for much longer, up to one week or more, versus PRP which releases growth factors for few hours. This means that PRF could have better longer-term benefits. The growth factors are what stimulate the stem cells to improve collagen and elastin in the skin. The platelets in PRF are thought to be more robust than those in PRP, and therefore promotes faster healing.


PRF has several advantages over PRP. Mainly:

  • It doesn’t need thrombin and anticoagulants, making it 100% natural

  • It results in better healing due to its slow polymerization process, making it longer lasting

  • It helps in hemostasis, the first stage of healing

  • Growth factors in PRF are 3X the concentration of traditional PRP

  • PRP can be combined with other treatments for even greater improvement

Mary C. DuPont, MD, FACS

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