Drug Discovery and Delivery

Equipped with one of these versatile electron microscopes, researchers can better study proteomes and the changes and patterns related to disease development and different conditions relating to this. Electron microscopy is used to look at various coatings or surface treatments on pharmaceutical actives, which can indicate uniformity, size, or surface morphology of the drugs.

Whether proteins, nucleic acids, liposomes or dendrimers, these samples are normally a major challenge to image in an electron microscope. This is due to inherent low contrast provided by their molecular composition.

Focused on materials characterization and morphology, the LVEM5 and LVEM25 can play a critical role in drug discovery efforts. Biomedical researchers are able to discover and identify compounds with medical bearing. Subsequently, they can design nano-sized drugs for use in a wide array of applications including cancer.

High contrast in TEM mode of most drug discovery related samples is offered by the LVEM systems. In SEM mode the lower voltage of the LVEM5 provides more information from the surface of the material. The LVEM5 takes only 3 minutes for its time-to-vacuum-ready condition, so the technique becomes high throughput. The cutting down on the time required to retrieve results allows medical researchers and professionals to have one of the best drug discovery microscope options with a LVEM electron microscope.

The LVEM5 aids the drug discovery field by providing high resolution images of a wide array of samples enabling researchers to obtain higher productivity and better conclusions. The LVEM5 electron microscope produces images of various sizes from the micron range to the nanoscale, allowing researchers to study the subject with a wider perspective. A diverse range of operating modes including TEM, STEM, SEM and ED, gives scientists a broad understanding of their samples.