If Deshaun Watson was supposed to come back down to earth Sunday, he must have missed the memo.

Facing one of the NFL's most dominant pass defenses, Watson didn't back down from the Legion of Boom and threw for 402 yards and three touchdowns in the Houston Texans' 41-38 loss in Seattle. He did throw a trio of interceptions but will go down in the league's history books as the first player to pass for 400 yards and four touchdowns and rush for another 50 in a single game.

The clear frontrunner for the Texans' first-ever Offensive Rookie of the Year award completed eight passes to former Clemson Tiger DeAndre Hopkins, who racked up 224 yards — the second-highest total of his career. Hopkins' 72-yard touchdown in the fourth quarter marked his sixth in his last four games, the most in the NFL during that span.

On the other side of the country, former Clemson teammates Chandler Catanzaro and Grady Jarrett squared off in East Rutherford, New Jersey, where Catanzaro's New York Jets lost to Jarrett's Atlanta Falcons, 25-20. Catanzaro missed a pair of field goals in the contest, which would ultimately make all the difference.

Meanwhile, Jarrett made his presence known in behind the line of scrimmage with half of a sack and a game-high three tackles for a loss.