@inproceedings{HeusermannNoethlingHansmannetal.1987, author = {Heusermann, U. and N{\"o}thling, R. and Hansmann, M. L. and Ulrichs, Karin}, title = {Immunhistochemische und immunelektronenmikroskopischeUntersuchungen zum Vorkommen von dendritischen Zellen im Pankreas der Ratte}, url = {http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-45689}, year = {1987}, abstract = {Dendritic cells, first described by STEINMAN and COHN in the mouse spleen and now called lymphoid dendritic cells (LDC), were investigated in the rat pancreas with the monoclonal antibodies 29AI-L. T. and MRC-OX17, which both recognize the la-antigen immunohistochemically and immune electron microscopically. la-positive cells with a dendritic morphology were found in the connective tissue of the cxocrine and endocrine pancreas. Immune e1ectron microscopically, the Ia-antibodies were 10- calized on the cell surface and in sm all vesicles. A small portion of the la-positive cells showed additional acid phosphatase positivity, i. e. were la-positive macrophages. The other la-positive cells were probably LDC, which may be important in the elimination of foreign antigens, e. g. bacteria and vIruses.}, language = {de} }