

The evidence that supports incorporating regular fasting days into your lifestyle has exploded in recent years. While weight loss is the benefit that receives the most attention, there are many other compelling reasons to make regular Cleanse Days part of your routine:

1. Support Your Cellular “Cleansing” Processes

When the body is managing a steady flow of nutrition from frequent meals or snacks, some processes can be put on hold. One of these processes is known as “autophagy.” This process works to break down the old, worn-out components within your cells in order to reuse the basic building blocks, such as amino acids, to support cell maintenance and growth.

Autophagy has been the subject of continuing research that points to the benefits of this fundamental cellular process for supporting metabolism, heart and brain health, and healthy aging (1). Autophagy goes to work while you are fasting on a Cleanse Day by cleaning up the worn-out parts within your cells and recycling them.

2. Improve Your Appetite Control

Many regular cleansers have noticed that their appetites are more manageable in the days following a Cleanse Day. Researchers have also noticed this unexpected effect of intermittent fasting, and are beginning to explore the phenomenon in greater detail. Scientific research has uncovered changes in appetite-regulating hormones that may explain the decrease in hunger many experience following a Cleanse Day (2, 3). While the investigation into this field is still new, the current evidence suggests fasting may be a tool to help reset your appetite.

3. Target the Worst Kind of Fat

Excess body fat is never a good thing, but it is even more concerning when fat accumulates around your midsection and surrounds your internal organs. This kind of deep belly fat is known as visceral fat, and has been linked to serious concerns for your health and well-being.

As part of an Isagenix System, Cleanse Days have been shown to promote greater weight loss and greater visceral fat loss than a heart-healthy, whole food diet in university-based scientific studies (4). These results show that completing regular Cleanse Days can not only help with weight loss, but can also help you lose more visceral fat.

4. Improve Insulin Sensitivity

Insulin is the hormone that enables your body to use the carbohydrates in the food you eat for energy. Insulin plays a critical role in keeping your blood sugar levels steady after you eat a meal, but your body can become less sensitive to its effects if you routinely consume more food than your body can use. One of the body’s natural responses to fasting is enhanced sensitivity to the normal action of insulin (5, 6). Along with a healthy diet and regular exercise, supporting normal insulin function can greatly benefit your overall health and help keep your metabolism in top shape.

5. Support for Healthy Aging and Overall Well-Being

Intermittent fasting, the fundamental concept behind Cleanse Days, is an active area of scientific research. New studies continue to identify benefits from fasting related to markers of healthy aging and overall well-being. For example, recent research has found that fasting can lead to improvements in circulation, cardiovascular health, cognitive health, and reduced oxidative stress (7-10). This promising research supports the potential benefits of incorporating regular Cleanse Days as part of a long-term, healthful lifestyle.

While weight loss remains one of the most popular reasons why people choose to do Cleanse Days, scientific research has identified many other unique benefits of intermittent fasting that are less obvious from the outside. If weight loss is no longer your goal, there are still plenty of reasons to keep Cleanse Days in your routine.


  5. Varady KA, Hellerstein MK. Alternate-day fasting and chronic disease prevention: a review of human and animal trials. Am J Clin Nutr. 2007 Jul;86(1):7-13.
  7. Froy O, Miskin R. Effect of feeding regimens on circadian rhythms: implications for aging and longevity. Aging (Albany NY) 2010;2:7-27.
  8. Mattson MP. Dietary factors, hormesis and health. Ageing Res Rev 2008;7:43-8.
  9. Anton S, Leeuwenburgh C. Fasting or caloric restriction for healthy aging. Exp Gerontol 2013;48:1003-5.
  10. Martin B, et al. Caloric restriction and intermittent fasting: two potential diets for successful brain aging. Ageing Res Rev 2006;5:332-53.