Genomes and Genes


Ivan O Rosas


Affiliation: Harvard University
Country: USA


  1. Tsoyi K, Osorio J, Chu S, Fernandez I, Poli S, Sholl L, et al. Lung Adenocarcinoma Syndecan-2 Potentiates Cell Invasiveness. Am J Respir Cell Mol Biol. 2018;: pubmed publisher
    ..Thus, inhibiting syndecan-2 expression or activity could serve as a potential therapeutic target to treat lung adenocarcinoma. ..
  2. Jacob S, Courtwright A, El Chemaly S, Racila E, Divo M, Burkett P, et al. Donor-acquired fat embolism syndrome after lung transplantation. Eur J Cardiothorac Surg. 2016;49:1344-7 pubmed publisher
    ..DAFES is a rare but likely underappreciated early complication of lung transplant as it can mimic primary graft dysfunction. Aggressive interventions, including ECMO, may be necessary to achieve a good clinical outcome following DAFES. ..
  3. KLIMENT C, Araki T, Doyle T, Gao W, Dupuis J, Latourelle J, et al. A comparison of visual and quantitative methods to identify interstitial lung abnormalities. BMC Pulm Med. 2015;15:134 pubmed publisher
    ..Moreover, HAAs were not associated with MUC5B promoter genotype. ..
  4. Doyle T, Lee J, Dellaripa P, Lederer J, Matteson E, Fischer A, et al. A roadmap to promote clinical and translational research in rheumatoid arthritis-associated interstitial lung disease. Chest. 2014;145:454-463 pubmed publisher
    ..Furthermore, recommendations are made to design multicenter collaborative studies that will expedite the development of clinical trials designed to decrease the significant morbidity and mortality associated with RA-ILD. ..
  5. Tsoyi K, Chu S, Patino Jaramillo N, Wilder J, Villalba J, Doyle Eisele M, et al. Syndecan-2 Attenuates Radiation-induced Pulmonary Fibrosis and Inhibits Fibroblast Activation by Regulating PI3K/Akt/ROCK Pathway via CD148. Am J Respir Cell Mol Biol. 2017;: pubmed publisher
    ..These findings suggest that syndecan-2 has potential as an antifibrotic therapy in radiation-induced lung fibrosis. ..