volume 89, issue 10, P1575-1585 2011
DOI: 10.1002/jnr.22704
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Hitomi Soumiya, Hidefumi Fukumitsu, Shoei Furukawa

Abstract: Maternal infection during pregnancy is an environmental risk factor for the development of severe brain disorders in offspring, including schizophrenia and autism. However, little is known about the neurodevelopmental mechanisms underlying the association between prenatal exposure to infection and the emergence of cognitive and behavioral dysfunctions in later life. By injecting viral mimetic polyriboinosinic-polyribocytidylic acid (Poly I:C) into mice, we investigated the influence of maternal immune challeng…

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