SMC5-SMC6 complex localization factor 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
30988157 IMR-90 Human YES

GO terms:

Biological Process:
DNA repair [GO:0006281],
cellular response to DNA damage stimulus [GO:0006974],
positive regulation of protein complex assembly [GO:0031334],
positive regulation of maintenance of mitotic sister chromatid cohesion [GO:0034184],
protein localization to site of double-strand break [GO:1990166],
positive regulation of double-strand break repair [GO:2000781],

Molecular Function:
protein binding [GO:0005515],
ubiquitin protein ligase binding [GO:0031625],
macromolecular complex binding [GO:0044877],

Cellular Component:
nucleosome [GO:0000786],
nucleus [GO:0005634],
nucleoplasm [GO:0005654],
cytoplasm [GO:0005737],
centrosome [GO:0005813],
site of double-strand break [GO:0035861],
nuclear inclusion body [GO:0042405],
cytoskeleton [GO:0005856],