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Renese Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

Renese (polythiazide) is a diuretic used as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, corticosteroid and estrogen therapy, and edema due to various forms of renal dysfunction, as well as management of hypertension used either alone or with other antihypertensive drugs. The brand name of this medication is discontinued, but generic versions may be available. Common side effects include low blood potassium or sodium levels, or an imbalance of blood potassium or sodium levels.

The usual dosage of Renese for diuretic therapy is 1 to 4 mg daily, and for antihypertensive therapy is 2 to 4 mg daily. Renese may interact with other drugs. Tell your doctor all medications and supplements you use. Renese is generally not recommended for use during pregnancy. It may harm a fetus. Tell your doctor if you are pregnant or become pregnant while taking Renese. This drug passes into breast milk. Breastfeeding while using Renese is not recommended.

Our Renese (polythiazide) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.


What is Prescribing information?


Renese FDA Prescribing Information: Side Effects
(Adverse Reactions)


Gastrointestinal System Reactions

  1. anorexia
  2. gastric irritation
  3. nausea
  4. vomiting
  5. cramping
  6. diarrhea
  7. constipation
  8. jaundice (intrahepatic cholestatic jaundice)
  9. pancreatitis

Central Nervous System Reactions

  1. dizziness
  2. vertigo
  3. paresthesias
  4. headache
  5. xanthopsia

Hematologic Reactions

  1. leukopenia
  2. agranulocytosis
  3. thrombocytopenia
  4. aplastic anemia

Dermatologic -Hypersensitivity Reactions

  1. purpura
  2. photosensitivity
  3. rash
  4. urticaria
  5. necrotizing angiitis (vasculitis) (cutaneous vasculitis)

Cardiovascular Reaction



  1. hyperglycemia
  2. glycosuria
  3. hyperuricemia
  4. muscle spasm
  5. weakness
  6. restlessness


Read the entire FDA prescribing information for Renese (Polythiazide) »


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