, Volume 31, Issue 5, pp 388-401

Psychosomatic Medicine: The Scientific Foundation of the Biopsychosocial Model

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The authors provide an overview of the field and summarize core research in basic psychophysiological mechanisms—central nervous system/autonomic nervous system, psychoneuroimmunology, and psychoendocrinology—in three major disease states—cardiovascular, gastrointestinal, and HIV virus infections.


Understanding the core scientific concepts and research findings of psychosomatic medicine should provide medical trainees with a scientific foundation for practicing medicine within a biopsychosocial model of care.