RT Journal Article SR Electronic T1 Nitrogen source regulates glutamine synthetase mRNA levels in Neurospora crassa. JF Journal of Bacteriology JO J. Bacteriol. FD American Society for Microbiology SP 880 OP 885 VO 136 IS 3 A1 Sánchez, F A1 Campomanes, M A1 Quinto, C A1 Hansberg, W A1 Mora, J A1 Palacios, R YR 1978 UL http://jb.asm.org/content/136/3/880.abstract AB Neurospora crassa glutamine synthetase mRNA was measured by its capacity to direct the synthesis of the specific protein in a cell-free system derived from rabbit reticulocytes. N. crassa cultures grown on glutamate as the sole nitrogen source had higher mRNA activities than did those grown on glutamine. The differences were about 10-fold when polysomal RNA was used for translation and about 5-fold when either total cellular RNA or polyadenylic acid-enriched cellular RNA was used. These data indicate that in exponentially growing N. crassa, the nitrogen source regulates glutamine synthetase by adjusting specific mRNA levels.