TY - JOUR T1 - Making Strides in Type 2 Diabetes Prevention JF - Diabetes Spectrum JO - diaspect SP - 299 LP - 302 DO - 10.2337/ds18-0031 VL - 31 IS - 4 AU - Albright, Ann L. Y1 - 2018/11/01 UR - http://spectrum.diabetesjournals.org/content/31/4/299.abstract N2 - The prevalence of diagnosed diabetes in adults in the United States, currently at 23.1 million people, has tripled in the past two decades (1). In addition, an estimated 84 million adults have prediabetes, putting them at increased risk of type 2 diabetes, heart attack, and stroke; only 1 in 10 know they have it (2). If interventions to slow the increase in and ultimately reduce the number of new cases of diabetes are not widely implemented, projections estimate that one in three adults in the United States could have diabetes by 2050 (3).Diabetes remains a leading cause of blindness, kidney failure, and lower-limb amputation, increasing these risks to 6–10 times that of people without diabetes (2). It also increases risks of macrovascular conditions such as heart attack and stroke by 60–80% (2). Fortunately, rates of heart attack, stroke, and cardiovascular disease (CVD) death have recently declined for many people with diabetes, but this has led to an exposure to and diversification of other outcomes, including increasingly diverse causes of death (4). Although CVD remains the leading cause of death for people with diabetes, its proportion has declined from half of all such deaths ∼20 years ago to one-third of all deaths today. As a result, other causes, including influenza, pneumonia, septicemia, and chronic liver disease, now make up a greater proportion of the deaths of people with diabetes (4). Furthermore, diabetes doubles the risk of physical disability; adults with diabetes who are ≥50 years of age lose independence 6–7 years before their peers without diabetes (5).Diabetes is the costliest of the 155 most common diseases in the country, at $327 billion in 2017, including $237 billion in direct medical costs and $90 billion in indirect costs (e.g., reduced productivity and absenteeism)—an increase of 60% from 2007 … ER -