@ARTICLE{10.3389/fmicb.2016.00894, AUTHOR={Fang, Yuting and Zhang, Limeng and Jiao, Yongge and Liao, Jingjing and Luo, Lifen and Ji, Sigui and Li, Jiangzhou and Dai, Kuai and Zhu, Shusheng and Yang, Min}, TITLE={Tobacco Rotated with Rapeseed for Soil-Borne Phytophthora Pathogen Biocontrol: Mediated by Rapeseed Root Exudates}, JOURNAL={Frontiers in Microbiology}, VOLUME={7}, PAGES={894}, YEAR={2016}, URL={https://www.frontiersin.org/article/10.3389/fmicb.2016.00894}, DOI={10.3389/fmicb.2016.00894}, ISSN={1664-302X}, ABSTRACT={Black shank, caused by Phytophthora parasitica var. nicotianae, is a widespread and destructive disease of tobacco. Crop rotation is essential in controlling black shank. Here, we confirmed that rotating black shank-infested fields with rapeseed (Brassica napus) suppressed the incidence this disease. Further study demonstrated that rapeseed roots have a strong ability to attract zoospores and subsequently stop the swimming of zoospores into cystospores. Then, rapeseed roots secrete a series of antimicrobial compounds, including 2-butenoic acid, benzothiazole, 2-(methylthio)benzothiazole, 1-(4-ethylphenyl)-ethanone, and 4-methoxyindole, to inhibit the cystospore germination and mycelial growth of P. parasitica var. nicotianae. Thus, rapeseed rotated with tobacco suppresses tobacco black shank disease through the chemical weapons secreted by rapeseed roots.} }