A British teen died in the Colombian rain forest after having a reaction to the hallucinogenic drink ayahuasca in a tribal ceremony, according to the BBC.

Henry Miller’s body was found on the side of the road in the remote Putumayo region, near Colombia’s border with Peru and Ecuador, in 2014, according to the BBC. His death was ruled as “accidental death by intoxication” in a report released August 29, following an inquest by the Avon Coroner.

Ayahuasca, also known as yage, is a brew made from the leaves of the Psychotria viridis plant and the Banisteriopsis caapi vine, according to Motherboard. Individually, these plants lack power, but when combined, they produce a psychedelic effect. Ayahuasca brew contains the natural hallucinogen dimethyltryptamine, or DMT. Following the ritual, ayahuasca users “tend to feel more accepting and at peace with their situation in life,” according to Motherboard. Brain scans have shown that the drug can decrease activity in the brain’s default mode network — which, when overactive, is reportedly linked to depression, phobias, and anxiety.

An ayahuasca experience differs from the “trip” that similar drugs like LSD or magic mushrooms might produce, Motherboard reports. Users of ayahuasca often feel the effects within 30 minutes of consumption and are usually fully aware that they are hallucinating. The acidity of the brew often makes people vomit during the ceremony, and the drug can elevate blood pressure and heart rate.

For centuries, ayahuasca has been used for spiritual and ceremonial purposes by South American tribes, who consider it a medicine to heal internal wounds and reconnect with nature, according to Vox. Research is beginning to show that it can help people work through traumatic memories, and neuroscientists are looking into ayahuasca’s effects as a treatment for depression and PTSD.

Use of the brew has become trendy with celebrities, like Lindsay Lohan, Sting, and Chelsea Handler, and adventurous tourists, who often shell out thousands of dollars, according to CNN, for an experience. Ayahuasca experiences are commonly portrayed as a “shortcut to enlightenment” or an “extreme tourist experience,” according to The Guardian, and ceremonies are also starting to pop up in Britain and the U.S.

The 19-year-old Miller, who was from Bristol, was called “an adventurous person who traveled extensively” and was traveling for his gap year. He reportedly attended a tribal ritual in Colombia two days before his death, where he also drank ayahuasca, but felt no effects. He returned to try it again, and soon after drinking the brew, began to feel unwell.

Miller’s family released a statement saying, “Young travelers should be made aware of the small but real dangers of this practice.”

There have reportedly been five known deaths related to ayahuasca in Peru since 2015. However, many ayahuasca ceremonies operate unlicensed and unregulated across South America.

