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EnzyBurn Review: Digestive Enzyme Supplement for Weight Loss

The world of health and nutrition is full of claims about weight loss. EnzyBurn is another voice in a sea claiming to help melt stubborn fat. They allege being able to lose 12 pounds of belly fat “almost overnight” based on research from a forgotten population of thin island inhabitants.

But does it really work? Or is EnzyBurn full of empty promises like so many before it? Please keep reading for a comprehensive look at the supplement and everything we know about it.

The Story Behind EnzyBurn

The creators of EnzyBurn focus on a story, mythic in its incredulous claims, of a picture-perfect couple in Florida named Stamatis and Simone Moraitis. They were a Greek immigrant couple with 3 healthy children and a business of their own, the American Dream by any standard. However, Stamatis had a cold-like cough that just would not go away.

He was given a death sentence by his doctors: terminal lung cancer. At the diagnosis, Stamatis had the urge to return to his homeland, a Greek Island by the name of Icaria, where he had spent the first 23 years of his life.

Miraculously, maybe even unbelievably, his lung cancer disappeared upon returning with the makers saying:

“Maybe it was seeing old friends. Or the Mediterranean climate. Or the healthier foods. Whatever it was, within a few weeks, his energy had returned.”

It wasn’t just his cancer that had disappeared, and his entire health had improved, losing a significant amount of weight during his visit.

“A few more months passed. His color returned. His skin improved. He lost 35 pounds simply eating native foods.”

Doctors apparently confirmed his cancer was in remission when he flew back to the United States after 9 months on the island.

I know what you’re thinking. This story is too fantastic to be true, and I agree. But the story is not really the point anyways- it’s Icaria.

Icaria was known for its famous longevity and thin residents, being called “The Island Where People Forget to Die” and “The Land Where Fat Vanishes.”

Apparently, research showed the bodies of people native to the island produced extraordinary amounts of a unique fat-metabolizing enzyme,” according to the website. This enzyme causes such a high level of fat burning so constantly, and it’s been credited for the thin appearance and lack of disease.

The makers of EnzyBurn decided to package this enzyme, seeing a unique business opportunity and obvious way to help people.

What Exactly Do The Makers of EnzyBurn Claim

Most digestive enzyme supplements are rightly advertised as digestive health aids, but this one is not only marketed as primarily a weight loss supplement, it claims other benefits as well.

Accordion to the website, EnzyBurn is good for the following:

  • Significant weight loss with little to no effort, claims estimate as much as 12 pounds lost within your first night of taking this supplement
  • Gas and Bloating relief
  • Reduces IBS and helps to prevent leaky gut
  • Reduces anxiety, pain, and chronic fatigue
  • Increases nutrient absorption
  • It helps digest lactose and glucose more easily
  • Helps clear skin
  • It helps prevent disease by boosting the immune system
  • It helps eliminate brain fog, increasing focus and memory

But how can a supplement help you lose 12 pounds in the first night? Or even the first few days! My first thought is water weight but let’s look at the ingredients and the science, see what we are working with.


How Does EnzyBurn Work

Enzyburn has two categories of key ingredients: probiotics and enzymes.

Probiotics are gut microbiota that live in the digestive tract, maintaining its function. If your diet and lifestyle are unhealthy, this can cause digestive issues because the balance of microorganisms has been thrown out of whack. Many people take a daily probiotic to offset any inadequate amounts from their diet and is generally a good idea considering the rise of gut-related health issues in Western Society today.

Enzymes aid in healthy digestion by processing the foods we eat. For example, if you feel bloated after eating a lot of cards, it is an indication that you do not have enough amylase, which helps the body transform starch and glycogen into simple sugars.

People Also Read: Best Probiotics

While both are vital for long-term health, their lack can also cause immediate and noticeable discomfort. EnzyBurn claims their combination of the two help the body appropriately process proteins, carbs, and fats.

EnzyBurn’s makers have unfortunately not disclosed dosages in their products, nor have they identified which ingredients are inactive. But their website does list what the ingredients are and their benefits:

Lactobacillus Acidophilus- the company claims this is a probiotic strain that helps the body break down sugars and prevent them from becoming stored fat. As a result, it helps “lower cholesterol” (a unique claim to this supplement).

Fungal Protease- the lack of this digestive enzyme is attributed to grogginess, bloating, and even feeling heavy after having too much protein.

Lactobacillus Plantarum- the makers of EnzyBurn claim that this probiotic “helps your body absorb nutrients,” act as an antioxidant, and rude hunger, but they don’t go into much detail.

Other Ingredients- Their normal EnzyBurn also contains alpha-galactosidase, similar to other digestive enzyme supplements. But they make a Super Blend Makzyme-Pro formula which also includes bromelain, papain, fungal lipase, and fungal lactase- a mix of three probiotics and one enzyme. Not much is said of them other than “the most effective ‘thinning enzymes’ on the planet.”

Show Us the Evidence

EnzyBurn has neither been studied nor tested, however, the makers still list more than 18 resources on a reference page backing up their claims.

Their standouts were this 2010 study where researchers analyzed multiple studies that have been used “with some promising results” to aid in weight loss while cautioning there was little evidence of significant weight loss.

Harvard Health also explained the genuine health benefits of probiotics, especially for digestive issues like constipation and efficiency. A 2015 survey on 12 studies involving more than 3 thousand people saw probiotics taken regularly could lead to fewer and shorter upper respiratory infections.

This 2020 study showed a small decrease in weight (just under 3 pounds), more so than a placebo group, over a period of 6 months when taking a probiotic supplement with 50 billion CFUs per day- which is a much higher dose than in EnzyBurn.

There is evidence showing probiotics and digestive enzymes are incredibly good for you, particularly for digestion and long-term health. But the claim that it can make you lose significant weight, especially overnight, is more than just thin on the ground.

Purchasing EnzyBurn

You can order EnzyBurn from the original website. The pricing is as follows:

  • 1 Bottle: $49 + $9.95 Shipping
  • 3 Bottles: $117 + $9.95 Shipping
  • 6 Bottles: $204 + $9.95 Shipping

If the user finds that they are unable to lose weight while taking EnzyBurn, they can request a refund with the 365-day money-back guarantee.


The Last Say

Personally, I am highly skeptical of any supplement company that lacks this much transparency and has so little backing it, particularly because the United States does not regulate the supplement industry almost at all. It is also worrisome that not a single study has been done on the product they are so certain it works this well, claiming the most outrageous results.

We should all be skeptical of a company claiming a 12-pound weight loss within the first few nights, and I would like to reiterate that any fruition of this claim most likely lends itself to having lost water weight rather than actual body fat.

However, EnzyBurn does have good probiotics and enzymes in it– although maybe not at the amount required to have the best effect.

As nutritional supplements go, it is suspect. The great news is that they have such a broad money-back guarantee that it shows clear confidence in their product. For anyone looking to boost their abilities to lose weight, this may be decent to try because the worst that could happen is being out a few dollars before getting all of your money back. What do you have to lose, really? Except maybe more weight.

To learn more about EnzyBurn, their mission as a digestive enzyme supplement, their claims, and anything else about the product, don’t forget to head to their website at, which is also the only safe place to order their product.

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