790368 Biological therapeutics (in Eng.)

Vortragende/r (Mitwirkende/r)
Radauer, Christian , Kunert, Renate
Angeboten im Semester
Wintersemester 2021/22
Unterrichts-/ Lehrsprachen



Dear students!

In the academic year 2021/2022, we are endeavoring to enable significantly more face-to-face operations than in the previous year. The primary goal is still the safety and health of all BOKU members. In terms of planning, the following rules apply (as of October 1st 2021):

* BOKU generally applies the 3G rule to protect everybody,
* It applies at all BOKU locations without exception.
* FFP2 masks are mandatory in all public places (e.g.: corridors, etc.).

Detailed information are given at the BOKU homepage.

The lecture will take place in seminar room 05/08 in the 5th floor of MUG1/DBT.

If you have any organisational questions, please contact my colleague Christine Prenner (christine.prenner@boku.ac.at)

Kind regards
Renate Kunert

recombinant proteins and biologics in human therapy: function, production and critical quality attributes

Coagulation factors, thrombolytic and fibrinolytic factors
Enzymes and hormones
Interleukines and Cytokines
Production of monoclonal antibodies, chimerization and humanization
Clinical applications of monoclonal antibodies
Production of recombinant antibody derivatives
Antibody mimetics

Inhaltliche Voraussetzungen (erwartete Kenntnisse)

students should have passed already the examination cell factories but at least need knowledge about generation of recombinant cell lines and propagation of cell culture


After having passed the course the students are able
- to transform their scientific knowledge for the development of biological therapeutics
- to assess development strategies and critically evaluate the quality demands of products
- to rank the scale of the production effort for up-stream, down stream and formulation procedures
- to explain data gained by in vitro studies and propose the products behaviour in vivo.