Artificial Activization with Calcium ionophore

What is Artificial Oocytes Activation using Ca2= ionophores and What are the Potential Benefits for Your Ukrainian Surrogacy?

Fertilization problems are the major problems that may be faced in 30-55% of the patients during an intracytoplasmic sperm injection (ICSI) cycle. A successful oocyte activation depends on factors related to both sperm and oocyte.

One of the important factors that mediates the process is Ca2+ concentration within the oocyte. Artificial oocyte activation (AOA) is a method used for fertilization problems that commonly involve the usage of Ca2+ ionophores and is usually used in problems such as total fertilization failure (TFF) and globozoospermia.

In order for an egg to allow a sperm to fertilise it and start developing into an embryo, it first has to be activated. In some women with previously failed fertilisation, even when advanced techniques such as ICSI are used, the eggs may be stimulated in subsequent cycles to activate by using chemicals called calcium ionophores.

These chemicals are added to the embryo in the lab.


At Delivering Dreams International Surrogacy, we use these advance technologies to do everything we can to assure your dream comes true – a healthy child!

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