Diabetes, Type 2
"I had frequent intestinal distress (and I mean distress).  Janumet is a combination of Januvia and Metformin.  I switched to two pills, Januvia and Metformin ER.  ER stands for extended release.  It may cost more this way, but it eliminated the problem.  Those of you with a similar problem should talk to their doctor.  Most don&#039;t know that Janumet itself  used the immediate release Metformin....which causes intestinal distress in many users."