Depression
"I have suffered from major treatment-resistant depression for 32 years.  I&#039;ve tried so many medications along with polypharmacy for this, and almost nothing helps.  The only antidepressants that are of any use are citalopram, buproprion, and Abilify.  Even this combination doesn&#039;t always work--usually the citalopram stops working after a number of months, and I have to switch it out for sertraline.

A few years ago, my psychiatrist tried adding 20 mg of methylphenidate twice a day.  What a difference!  I am now able to get out of bed, work, focus, smile, and have something that approximates a normal life.

The only problem with this, is that I am now completely dependent on the methylphenidate in order to function."