Peripheral Neuropathy
"I&#039;m a 74 year-old woman who has had peripheral neuropathy for about 7 years. None of the meds prescribed gave me any relief until I was started on Cymbalta. It seemed miraculous, as within a week or so I had almost no pain or burning in my legs and feet. I&#039;m on 60 mg daily, along with oxycodone (7.5 mg twice daily). In the last couple of years the Cymbalta is far less effective than it was initially, and I would have even more pain if it weren&#039;t for the oxycodone. I asked my doctor about increasing the Cymbalta to 90 mg, but he says you don&#039;t get much more relief beyond the 60 mg dose. It&#039;s very disappointing to have the effectiveness decrease. Side effects are weight gain and sensitivity to heat and sweating."