Motion Sickness
"Been dealing with motion sick type issues for years. Meclizine does not work, regardless of the dosage- even if taken at the first onset of symptoms. It has been totally useless for me. In fact, the only thing that does work is Diphenhydramine.  Dramamine is NOT the same. It may have Diphenhydramine in it but they combine it with chlorotheophylline to reduce the sedative effects. It must alter the entire chemistry of it or something. They rename the active ingredient Dimenhydrinate, much less effective than Diphenhydramine or Benedryl... 
Anyways, I gave the Meclizine two stars because I never notice any adverse effects from it despite being very sensitive to medications...  I know some people it works for, just not me."