Constipation
"Had a weeks sample of Linzess 290 after feeling backed up and having small hard bms for a year. Definitely did the job when taken as directed. Cons would be the &quot;oh no I may poop myself in public&quot; feeling, which happened a few times, and realizing not to take it if you have nothing in your gut from the previous day. My gut actually started feeling normal for the first time ever. Took a week to get a prescription, and my symptoms immediately returned. Restarted the script, which again works nearly immediately. Although this time around, maybe just by chance, I developed my first cold in 13 years, with symptoms start in the day I restarted Linzess . Now I am riding that out. Plan to continue med as long as this cold disappears."