Depression
"It takes about 2 weeks to feel Wellbutrin kick in and about a month for it to be full effect. I am on 300 mg a day and take it in the morning only. If you take it too late it will keep you awake. I am on other med for Bipolar that cause weight gain, but this med seems to be the opposite and has actually helped me lose weight. Sometimes the med &quot;runs out&quot; in the afternoon and you can kind of feel the let down. It works great for depression and would be good if used by itself for weight loss. Would recommend using it, but you have to be patient with it."