"I have been on all anti-anxiety medicines (lexapro, paxil, effexor).  Personally, when I take an anti-anxiety medicine that is also used for depression, I do not respond well at all.  Even with dose adjustments nothing worked well.  I was prescribed Klonopin five years ago. It last longer than Xanax and in my opinion is more effective for me. I started on 0.5mg 2 xs a day.  Now I&#039;m at 1 mg 2 x a day.  That&#039;s not very much. I&#039;m 200 lbs."