Sedation
"I can&#039;t say this drug has NO effect, but I&#039;m a chronic insomniac and have been treated for it with Xanax or Klonopin for at least the last 20 years.  While mild doses of those drugs have induced sleep, when I&#039;ve desired more sleep than those &quot;benzos&quot; have allowed me, I&#039;ve tried Promethazine in varied doses, from 12.5 to 75 MGs and it just doesn&#039;t induce sleep like I had hoped.  It&#039;s very effective for reduction of nausea, but I&#039;m lucky if it barely makes me drowsy.  Sometimes, even the higher doses had no effect at all. BOTTOM LINE: This med gets great reviews, so it works for some, but I&#039;m proof that it&#039;s not effective for EVERYONE."