"I have been taking Seroquel for over a year, and was on 600mg a day! Such a high dose I thought I would see a lot of improvement. I have been on Saphris, Asenapine to treat my schizophrenia for the past month (5mg in the morning and 5mg at night) and have been feeling much more clear minded, better concentration, better mood.  Now I am reducing Seroquel and it is hard!! I have been shaking, hands And I will continue to reduce Seroquel. I would recommend Asenapine to anyone.  Finding life is a bit easier on Asenapine.  The first day I took it I was off my face for half the day and then took a nap too.  By day 4 on asenapine I felt so much better.  Hope this could help someone."