Migraine
"I have suffered from migraines since I was 20 and am now 34. I have tried countless abortive medicines.  Sumavel is the best one by far because it relieves the pain and nausea fast (usually within 10 mins for me).  The injection is painful and leaves quite a welt but far worth it to get relief.  I do sometimes have issues with it not firing properly but it could be just me pulling back at the last second when I anticipate the pain coming.  I have wasted quite a few shots this way."