Thrombocythemia
"I am 80 years and have been taking this drug for 7 years without problems, it kept my platelets around 600,000. Then I developed open sores on my fingers. A blister would form, pop, and then the sore would be exposed and wouldn&#039;t heal for weeks. After that I developed wounds on my ankles. I developed  3 open, non-healing ulcers on my ankles that were so painful I had to go to the hospital. All the while my hematologist, my primary doctor and all the hospital doctors shook their heads and said they didn&#039;t know what was wrong. Then my son did a google search and found that these horrible skin ulcers and sores were a rare side effect of the hydroxyurea! I am now off the drug and with a new hematologist and a new drug Jakafi."