Pain
"Opana ER is the 1st ER medication that I&#039;ve tried that actually works for an extended period of time. And I&#039;ve had to try many for my severe back and neck injuries. One 20mg pill will last at least 8 hrs, and I work long 16 hr days so that&#039;s a very good thing. I highly recommend it for people with severe problems/injuries. I definitely wouldn&#039;t recommend it for just mild to moderate pain problems or acute problems. Most ideal for people with chronic severe injuries who also work a lot."