Chronic Pain
"&quot;Duragesic&quot; is an excellent chronic pain medication:  no euphoric issues following the first couple weeks of use and initial body adjustment, etc., steady pain relief with minimal &quot;Ups and Downs&quot; in effectiveness (i.e., break through pain).  However, myself, as with many users, find that it is necessary to change the patch every 48 hours, vs. the potential 72 hours (i.e., obviously this is with your doctor&#039;s approval). Also, putting the patch on takes a degree of practice and again, as with many, find it necessary to cover it with an approved &quot;3M Tegaderm Cover&quot;  to prevent premature loss of adhesion. "