Constipation
"I am on methadone maintenance. I have been on  it for years. It causes serious constipation for me. I had to manually pull it out! pain, bloating, you name it. My Dr gave me samples of Linzess. I took it at 2pm, and just took a seriously satisfying poop . Miracle drug. No side effects, yet. I strongly recommend for anyone chronically constipated."