Pain
"I took Ultram for over a year after herniating a lumbar disc.  Apart from fatigue, a little dizziness and the usual constipation that seems to accompany most pain medicines, I had no major side effects.  It did not eliminate the pain, but decreased it enough for me to function for the most part (sit, drive, sleep).  However, over time my system became accustomed to the drug and it did not work for me anymore.  Thankfully, I had minimal withdrawal symptoms.  I have since tried Neurontin (Gabapentin), Nortriptyline and Topamax for chronic pain, with mixed results, and significantly worse side effects.  Still no long term solution for the pain."