Acne
"Developed flu like symptoms the evening after I took first and only dose. Soon after developed acute hives and ill feeling for several months then additionally turned jaundice. Went to GI and connected it to the minocycline.   Took 3-4 months to monitor and bring liver levels back to normal (they were elevated 16 x the norm).  Had similar situation 5 years back but hadn&#039;t connected it to the minocycline at that time.  Had used the minocycline for a few months then. Must have developed severe reaction now to cause so much trouble with just one dose. Red Cross won&#039;t accept my blood donations now.  Bad stuff. Don&#039;t recommend it to anyone"