Urticaria
"I have had pretty severe CIU for a couple of years now.  Before the Xolair, I was taking cyclosporine BID, plaquenil BID, allegra BID, ranitidine BID (and other various doses and combinations of antihistamines to no avail), prednisone PRN (whenever I developed angioedema, which was a few times/month), and I was about 50% controlled (once or twice daily, mild to moderate outbreaks with severe outbreaks about 1x/week).  I was able to add Xolair last June.  It took a few months and I have not been able to get off any of my other medications, but I am at &gt;90% control.  I feel like I have my life back. =)  I am still hoping I will be able to get off some of this other stuff, but at least I feel normal again."