ADHD
"Our 6-yr-old daughter has been on this for 6 months.  At first we also thought it was a miracle drug. Her handwriting improved tremendously, her attention span was great, etc., however, it did wear off around 3 PM and we were in for a horrible evening every night.  We tried a booster of 10 mg of methylphenidate at 3 PM but that has just brought out oppositional-defiant disorder.  We now are about to try Concerta.  I definitely would recommend Metadate CD, though, because for the most part it gave us back our daughter."