Pain
"I was in a very severe auto accident where I went over a cliff driving up to the mountains.  Pain mamgement doctor tried everything from morphine to fentanyl but these medicines caused quality of life issues (felt slow or ephoric).  Now take 20 mg Oxycontin twice daily with 8 5/325 Percocets for break through pain. Miracle drug.  No ups and downs, no side effects."