Pain
"I have been on these patches for about 2 years. I started out on the 25 Mcg&#039;s and now am on the 100 Mcg&#039;s, and I change them every 48 hours. They work great. I also am on Oxycodone 15&#039;s 1-2 every 4-6 hours for break through pain, but I usually do not need to take them that often. I have a rare muscle condition that causes extreme pain. during the years prior to being on these I  have been on just about every type of pain medication,(narcotic and non-narcotic) that you can think of. I must say that these are by far the best and I would recommend them to anyone that has real issues with pain. they are not for people that just have occasional migraines or back pain."