Pain
"I have been on MS-Contin for 15 years.  In that time, only one dose increase!  I take 2x60 mg daily.  Every 2-3 months, my doc changes medicine.  I used to be able to get Opana, 40 mg 2x per day, and it worked great!  Even better was Efalgo, 16 mg 3 x per day.  2 in the morning, one at night.  Now, insurance will not pay for either.  The only medicine I can tolerate is Opana, 80 2x per day, and they really don&#039;t work well.  It is so frustrating that the medicine that is the hardest to tamper with, Efalgo, is the hardest to get and most expensive! If I don&#039;t switch every few months, I build up a tolerance. I suffer from degenerative disc disease in my lower back, arthritis etc."