Depression
"Started out on 150 mg of bupropion hcl xl and saw results after 7 days of use.  By day 30, I was feeling great about 80% of the day, experienced usual depression issues late at night.  Next month my Doctor upped my dosage to 300 mg/once a day in the AM. Feeling better at night now after the increase.  Another bonus--dropped 11 pounds in the first month.  Motivation is better and getting things done."