Headache
"I was terrified when Midrin was discontinued.  This was the medicine that replaced it, and I hoped it did just as well as Midrin did at knocking down the headaches.  It did!  I am terribly sensitive to caffeine, but the amount in this didn&#039;t cause a reaction in me.  I didn&#039;t notice much of any side effects other than a little fluffy-headedness.  Normally my migraines last a few days, and in the course of a headache episode I could take 30 or more Tylenol.  I usually take one Esgic as soon as my headache starts and that&#039;s the end.  One pill and hardly any discomfort, compared to 30 or more Tylenol that barely mask the pain."