Pain
"Very effective for pain relief.  For me the itching and long lasting (up to a month after use) red squares in all areas where the patch has been applied are serious setbacks. Several solutions have been suggested but none of them have helped. Because of the itching and the efforts to reduce it, the patches tend to fall off. It seems I scratch the area at night and dislodge the patch. Any abnormal stress in my life tends to aggravate these side effects. But as stated they work for pain relief."