Pain
"Been on Duloxetine for 4 weeks now at 30 mg. First day had terrible diarrhea,  then felt groggy and almost in a dream like state for the first week. I was prescribed Cymbalta for migraines and general anxiety. Week 2 started to feel more normal but my anxiety was worse (to be expected). Week 3 I  noticed my migraines were less frequent and I tolerated the pain better, also started feeling happier and less anxious. Week 4 my anxiety is almost gone n migraines have gone from daily to maybe every 3 or 4 days and are less severe. Worth the first two weeks of feeling crappy."