Renal Cell Carcinoma
"Began 800mg in May 2014; 10 months into treatment. No new mets at this  time. High blood pressure began three weeks into treatment, a good sign in that it demonstrates the drug is working well. Hand foot syndrome, initially intense pain , but now under control. Weight loss due to loss of taste  and appetite, a nutritionist can help. White hair. This is considered the least toxic targeted therapy drug for mRCC, do all you can to stay with it. If it is working for the first year you may continue to get excellent results for years to come. This is currently considered the first line therapy for mRCC. Take at night to reduce the stomach discomfort."