ADHD
"I started taking generic Buproprion XL at 150mg once a day to help with lifelong focus problems and lack of physical energy( ADHD-PI (Inattentive Type)). I was told that this was an off-label treatment and that it might not work, but I was interested in the long half life of the active metabolites and wanted to give it a try. The focus and wakefulness that it restored were very promising, and initial hypertension and blood pressure artifacts faded by the first day. However, there was a persistent lack of ability to easily recall facts or synthesis new ideas and my normally bubbly and chipper mood was blunted to moderately lower level. After day three, I quit. I think the nicotinic antagonism inhibits memory and critical thinking for me."