"Debated long and hard, but finally asked my OBGYN for Wellbutrin XL for hormonal mood issues. I work for a psychiatrist so I&#039;m well informed of my options and felt this medication was my first choice for symptoms and fewest chances of unwanted sexual and weight gain side effects.  2 weeks into treatment at 150mg.  Feeling an overall clear and light heartedness.  This week should be the height of my PMS and I am not cranky!  Also helping a lot with decreasing appetite and smoking is very unappealing.  Very minor stomach unsettle, and I&#039;ve been waking more in the middle of the night, but side effects generally mild and tolerable.  May ask to increase dose to 300mg.  I wish I had asked for this medication sooner!"