Pain
"Ibuprofen was my default pain relief early in my experience with Ankylosing Spondylitis. It reduced inflammation and made the pain, discomfort and stiffness more manageable. 

I did experience some side effects (constipation, followed by diarrhea due to the blockage, stomach pains etc., but the pain management helped to make it bearable. I managed on it for over 10 years before my fusion made the pain worse."