Insomnia
"I have bipolar 1 disorder and though I manage my condition with lithium, I have trouble getting to sleep at night which leads me to insomnia which ultimately leads  to manic episodes. I take between 12.5-25 mg a night of the seroquel and it works within about 45 minutes or an hour. It puts me right to sleep. It&#039;s the only medication that has ever consistently worked on putting me to sleep. I feel a little bit groggy in the morning sometimes if I take 25 mg. Also it increases my appetite at night. I&#039;ve probably put on a little bit of weight because of my snacking but it&#039;s so worth it to me."