Major Depressive Disorde
"I&#039;ve been on Rexulti for about 2-3 months after taking Abilify for about 10 years, which I had to quit for various reasons. 
Rexulti is great for my depression; I&#039;ve had zero anxiety, and it&#039;s really the only drug out there that works for me at this point. 
I didn&#039;t give it the full 10 points for two reasons. The first reason is I get really hot when I go outside in moderate, 70 degree temperatures. I can&#039;t handle hardly any heat! Second, while 2mg works great now, getting up to that dose is hard! I was sleep-deprived for the first month on 1/2mg, and until I got up to my current does, I didn&#039;t sleep very well. 
One other thing, this medication does better for me without Topamax! Apparently Topamax can minimize the effects of Rexulti!"