"I&#039;ve been taking Tri-Sprintec for 4 years, it works well to avoid pregnancy and regulate my period, but I&#039;ve gained almost 20lbs and I have spurts of intense anger and sadness. Sometimes I&#039;m really hungry and other times I can&#039;t eat a thing without feeling sick and bloated. Sex is usually painful, but my sex drive has escalated greatly, especially the week after my period."