Pain
"I was on three 10mg ERs per day and it was wonderful.  Low side effects, did not need to increase dose even after years. Now that they&#039;ve pulled it, I&#039;ve tried oxycontin (20mg twice/day) and then Exalgo (8mg once/day) and neither works as well as the Opana.  I have lupus and OA (need joint replacement)."