"This is the second time i have been on TriNessa and it is not working for me. I regularly get very moody and overly sensitive to everything followed by crying for nothing. I have had blurriness in my right eye and severe migraines almost everyday. I originally went on Trinessa for acne, it didn&#039;t help at all, it actually got worse. And I noticed that my periods are longer and cramps are a lot worse."