Depression
"I have tried almost all antidepressives drugs available in the last 20 years. 
Fluoxine, sertraline, paroxetina, citalopram and escitalopram did not work and destroyed my sex life.
Bupropion increased my anxiety a lot.
Mirtazapina caused me hallucinations and insomnia.
Venlafaxine and desvenlafaxine worked a for some time, but affected my libido and erection.
Niacina (off label) did not work for me.
The only one that worked and is still working is Tramadol (off label).
It starts to work about 1,5 to 2 hours after I take it, and lasts for 8 to 10 hours.
I take 1 50mg capsule first in the morning and another 1 at around 4pm, with empty stomach.
The ONLY drug that works for my depression and anxiety."