Irritable Bowel Syndrome
"Half hour after the first dose, taken on an empty stomach first thing on waking I had to RUN to the loo and had an explosive BM. After this it failed to work again ( as was my experience with Epsom salts, very similar) . 
I did  however get very bad bloating gurgling sloshy sounding belly, felt tired and nauseous amd thirsty needing 4 glasses of water at night. Bloating was far worse than my usual ibs symptoms , and no further bm after 6 days on the drug. Just felt toxic and my face was puffy....so I discontinued its use. Back to low FODMAP diet and enemas when necessary, which is often the case. I was so hopeful after first dose, but think severe bloating affects the nerves and hinders reflex of evacuation in my case. "