Depression
"Compared with the traditional SSRIs I would say that this is a gentle drug   You can feel the increase in serotonin nevertheless. I have CYP issues so am starting on 2.5. And it&#039;s ok so far. I think it reacts with the quetiapine to increase unwanted sedation. I have had no big s/e and I really feel Docs should start this low. None of us take meds for fun. With severe depression mixed with GAD I am cautiously optimistic.   It&#039;s expensive so if you&#039;ve bought some and are struggling I seriously advice lowering the dose and I hope you get the benefits in due course. Old Dodgy"