Motion Sickness
"I have tried meclazine as a prophylactic to motion sickness while fishing in the Gulf of Mexico with mixed results. 

The first time out was a complete failure with severe nausea and vomiting accompanied by diarrhea. The second time was a little better, no diarrhea and limited vomiting but quite acute nausea. 
Won&#039;t use it again for this purpose, probably won&#039;t go out on the gulf anytime soon either,

No noticeable side effects with either event."