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"I have liked depo, but today I started bleeding for the first time in a while, I was told I probably would bleed after my second shot (1/2 through my 3rd).  I came here to see if this was common.  I have gained 18 lbs while on depo (I was underweight so this is good, but 18 lbs???).  They said my appetite would increase but my metabolism seems to have gone down as well.  This shot makes you gain weight besides the additional eating, trust me.  I retain weight much easier which is a con if I were to take this after being pregnant!!!   I had terrible acne as well for about a month after I initially took this as well.  Overall I like it but wouldn&#039;t recommend it to a woman that just had a baby.  Vasagel will be out soon and we&#039;ll go that route"