Endometriosis
"I&#039;ve been on the Depo-Provera injection since the 1994 inception of off-label use for Endometriosis. For the last few years I&#039;ve started having some side effects over the two - four weeks prior to each injection including severe fatigue and hot flashes.  I&#039;ll take those side effects any day compared to how I lived when my &quot;Endo&quot; ruled my day to day life.  I&#039;ve been pain free for years as a result of the 15 years of Depo injections. Other side effects?  I guess we will see."