Depression
"I started 150mg of Wellbutrin XL in Jul 2013 due to feeling very unmotivated, depressed, tired, and hopeless. After a few days I felt good, and by the second week I felt better than I had in several years. I increased the dose to 300mg in Oct because I was starting to feel down again. It helped a lot but by Jan I was very irritable/angry/bitter, so I lowered the dose to 150mg and restarted 40mg of Prozac and the anger subsided. To address some side effects: inability to fall asleep (went away after 2-3 weeks), increased libido (awesome), pretty much the same appetite (no weight loss or gain), vivid dreams (sometimes disturbing), more emotional (but not crazy/extreme), constipation (moderate-severe), sensitivity to caffeine (must avoid)."