Depression
"Effexor XR really has been working wonders on my life. It has relieved me of a lot of my depression while still giving me my energy, unlike SSRIs. If weight gain is a problem for you and you have depression, definitely try an SNRI first. As you may or may not know, Wellbutrin is another antidepressant that is supposed to encourage weight loss while relieving depression. It affects norepinephrine and dopamine. I tried Wellbutrin awhile ago, and failed miserably on it due to the anxiety it brought on. Therefore, I was hesitant at first because I heard that Effexor XR affects norepinephrine as well. However, it has been completely the opposite. I have gone from constantly laying in bed all day long to wanting to get up and exercise."