Birth Control
"Although the convenience of only once a week is fabulous, the patch made me a complete emotional mess, there is no other way to say it.  I was on the pill for 20 years with no side effects at all, so it has to be the extra estrogen.  I could not even wait out the first month before I simply had to take it off.  I suppose it may have gotten better, but I was irritable, over-sensitive, depressed, anxious and generally felt like I was going to come out of my skin. It also increased my appetite noticeably.  Within hours of taking it off, I felt more calm and more myself."