Pain
"Was taking 10 7.5/325 daily for severe auto immune joint foot pain and nerve pain.  60mg time release. 9 out of 10 days I&#039;m fully functional like a normal mom.  My only issue is IBS... if I take in the AM and have my guts evacuate I am forced to suffer with only my 3 daily allowed break through pain medication.  Then if I don&#039;t double up the break through the withdrawal symptoms cause my guts to keep dumping.  I have slow digestion and it works about 19 to 22 hours.  I imagine a regular digestive system would burn through this medicine before 24 hours.  I tried it at night first and really enjoyed waking up without pain but had trouble the last 3 hours before the next dose. I would rather spend those wasted hours in bed each morning."