Rheumatoid Arthritis
"I have been on Plaquenil for 11 months. It took 6 months to the day for it to start working and then, heaven set in. The pain diminished significantly. I have a flare up now, for the first time and wondering what to do. I&#039;ve taken Aleeve, but no luck. I only seem to have a flare up during that particular time of the month, maybe something to do with water retention or hormones. Only side effect so far is upset stomach, take with food and in the middle of the day and much better."