Depression
"I&#039;m a 52 y/o male. I&#039;m on bupropion for Major Depressive Disorder.  In the past I&#039;ve been on Zoloft, Effexor XR and Cymbalta.  There is really no comparison; once I settled in with Wellbutrin, I just feel &quot;normal&quot;. I don&#039;t have that &quot;zombie&quot; effect you get on SSRIs and SNRIs.  My sex drive is fine and there are very few side-effects.

The first 2 weeks were tough. I was extremely nervous about side-effects so I went with the IR version, that way it wouldn&#039;t be stuck in my system for a couple of days if the first dose or two didn&#039;t go well.  I am now up to 100mg 3 time/day and doing fine."