Gout
"I rarely had gout flare ups despite having high levels for 10 years, I couldn&#039;t take the allopurinol, and when I started having small more frequent flare ups my doctor urged me to try Uloric, warning me that I was damaging my joints even if I wasn&#039;t having flare ups.  The first 4 months on it I had probably 7 flare ups, more than I had ever had before, but my levels were low.  Finally after 6 months they stopped and I have had zero issues for months. I think that what happens is that you build up crystals in your joints over the years if you don&#039;t treat your gout, then when you go on this medicine your levels drop so fast that the crystals dissolve and fall out into your joints.  Stick with it, it&#039;s worth it.  Not sure what it costs."