Pain
"Been taking Opana for about 4 years now. It&#039;s the best medicine I have ever taken.  I folded up my neck in an ATV  accident. Have a failed 4 level fusion with steel plate and 4 bolts 1/4&quot;, 3 discs removed. Also have 5 deteriorated disc, and two more spinal surgeries since first one. I have had to increase my dose to a 40mg every 12 hours or so, and up to 6 IR 10mg each day. Since the pink 10 IRs have been off the market, the white generic 10 IRs are not the same. Take this on an empty stomach for best results. And to the one patient in a previous comment who was trying to get his nerve up to ask the doc to reduce his dosage, I would say it was really in his own hands. Reduce it yourself if you really think you don&#039;t need it."