Constipation, Drug Induced
"This is the best medicine available for drug induced constipation, there is no doubt in my experience.  My one concern is that it does involve some urinary retention, certainly when I was given the maximum dose of 12mg.  The lower dose of 8mg caused less urinary retention but I am only using Relistor once a week until we assess how much retention it is causing, by ultrasound.  The manufacturer is still saying urinary retention is not a side effect. I note the comment of urinary retention here.  This could be a serious problem for those of us with underlying disease that involves urinary retention, such as ALD or some forms of MS, for example. Relistor is a great help otherwise."