Pain
"My doctor wanted to try me on Nucynta for my sciatica pain since Ibuprofen and Ultram did not work very well.  I tried one dose Friday night 75mg, and woke up Saturday morning with a horrible headache.  Then an hour or so upon getting out of bed, it turned into the worst headache of my life and then had nausea and vomiting with it.  I wound up having to go to Urgent Care and they gave me a shot of Toradol for the headache and a shot of Phenergan for the nausea and vomiting.  I finally felt better after awhile.  These side effects were too horrible for me."