Depression
"I have life-long treatment resistant depression and I&#039;m taking a SNRI, recently started Lithium Carbonate as augmentation. It just makes me very tired at the starting dose. Although I&#039;ll try, I don&#039;t expect increasing the dose will help and feeling so tired is very counterproductive for me. Also, have the typical thirst and no appetite. If it causes weight gain, that will make it even worse."