Restless Legs Syndrome
"I have severe RLS that is a problem during the day as well as night time.  I take Mirapex 0.25 mg twice a day, which greatly increases my comfort levels and the ability to hold relatively still.  Note:  I am confined to a wheelchair, with idiopathic polyneuropathy, along with Ehlers-Danlos Syndrome (and numerous additional diagnoses), and currently take 29 other prescription medicines, so I am unable to comment on side effects.  I have tried other drugs for RLS, including Lyrica, Klonopin, Neurontin, and clonidine.  For me, Mirapex and Lyrica relieve RLS far better than the others."