Pain
"I&#039;d like say there are many misinformed people here. Tramadol DOES help all kinds of pain. Tramadol is an opioid, it attaches to the same receptors Oxycodone does, and it&#039;s a PRODRUG -- meaning it must metabolize via CYP2D6 liver enzyme to work. 
Once it&#039;s converted over, it turns into M1 aka o-deso (for short) which is 6-10 times more potent than Tramadol, where it&#039;s real pain relief comes from. So People giving it 1 star? 
They are lacking proper metabolism OR they are taking a P2D6 inhibitor (some antiacids, like tagament), grapefruit juice, among others. 
A 50mg Tramadol tablet in studies has SUPERIOR pain relief to 40mg codeine+300mg Tyneol, and also showed the same pain relief as 5 to 7.5mg of Oxycodone. It works for pain..."