Bipolar Disorde
"I will give this a 2, simply because of the ease of use.  The tabs dissolve under your tongue so you can take them anywhere.  You cannot eat or drink for 10-15 min afterwards, which is really not a big deal.

I am bipolar I with occasional mixed episodes and was prescribed this medicine (5 mg 2x daily) in the middle of a mixed episode while in the hospital.  It propelled me into full-blown mania.

As with all medicines and this disease, its very personal.  This medicine might be more appropriate for someone less prone to mania than myself.  I am on Topamax 150 mg (50 mg 3x daily) and Seroquel 100 mg nightly, now.  I am not cured by a long shot, but I am certainly a lot better now, a month later, than I was on the Saphris."