Restless Legs Syndrome
"I wanted to post a little more information on Tramadol for RLS because people here are having a lot of questions/concerns. 50mg of Tramadol once or twice a day is not going to greatly improve your RLS. For restless legs, this medication needs to be taken in doses of at least 100mg and for it to completely get rid of the restlessness, it needs to be taken 2-4 times a day. And while other opiates like Oxycodone or Hydrocodone start working right away, Tramadol can take up to 1-2 hours to feel the full effect. So your last dose should be taken a hour or 2 before bedtime. Tramadol does nothing for pain but for RLS, it is a God send. The max dose is 400mg in 24 hours with no more than 100-150mg taken at once."