High Blood Pressure
"Everyone&#039;s physiology reacts uniquely.  Calcium channel blockers cause my ankles to swell.  One beta blocker didn&#039;t work; another worked for 10 years before stopping.  Alpha blockers gave me orthostatic hypotension.  The perfect combination seemed to be an ace inhibitor and a diuretic, but the diuretic gives me dangerously high uric acid. It lowers fluid volume and decreases the kidney&#039;s ability to excrete uric acid. Losartan is the only BP medication that lowers uric acid, so I was switched to losartan with a small dose of HCTZ.  Working well so far."