Depression
"Male, mid 30s, depression for ~10 yrs. Was on Cymbalta 60 mg QD for 2yrs, wasn&#039;t working, depressed, so up&#039;ed to 90 mg QD. Didn&#039;t work, had typical side effects. Cross tapered to Brintellix over 3wk period achieving 10 mg QD dose. Felt good for 2wks - more energy, sharper mentally, but very angry and irritable. Then all &quot;good&quot; effects ceased; all I felt was continual anger and irritation, which worsened every day for 3wks. Put on 12lbs/1mo while being on Brintellix. Stopped 10 mg dose cold turkey for 1wk, just started on Fetzima. Can&#039;t tell if Brintellix withdrawal or Fetzima, but now having sexual AEs, namely near spontaneous ejaculation without being erect or stimulated - any other men have this with either drug?"