Pain
"I&#039;ve found that Nucynta (Palexia in Europe) has been a great for me.  I&#039;ve had lumbar pain on and off for 35 years.  For the last seven years it&#039;s been chronic, sometimes incapacitating.  I was on the hydrocodone ladder (5, 7.5, 10), (x4, x6, x8,  per day) until a doctor where I work said &quot;Whoa!  That&#039;s way too much Acetaminophen.  It&#039;s dangerous.&quot;  He prescribed Tramadol.  It helped somewhat - and had an upper limit (for me) of about 300mg/day before nausea set in.  A year and a half ago he suggested I try Palexia (the trade name in Europe).  What a difference it made!  Some tolerance (not much) and no dependence I can discern, nothing like the &quot;codones&quot;.  Easy to lay off it whenever.  For me it&#039;s great!"