Osteoarthritis
"I find that right after I open a new tube the gel works great on my knees but with in about 4-5 days the same tube has lost a lot of its strength I recommend buying the smaller tubes to keep the strength up. Another person who I know also noticed this and thought it was just him but I have been using it for over a year now and the regular strength and the extra strength are both less effective after the seal has been opened 4-5 days."