atigue
"Provigil (modafinil), literally changed the entire course of my life! I was prescribed this medicine for off-label use to treat depression &amp; acute chronic fatigue. I also have BiPolar II, and I have had only minor difficulty with increased mania. The only reason I did not give this amazing medicine a 10 Rating is because I have experienced issues with building tolerance - that is - its effectiveness began to subside about 5 months after I began to take it. At that time I was taking 100mgs once a day in the mornings. My Dr. and I decided to increase the dose to 150mgs once a day in the morning and I felt terrific again! It&#039;s about 6 months later now, and again the amazingly wonderful effectiveness has decreased a great deal."