27</span> users found this comment helpful.
"I had to have a total hysterectomy in 2009 including removing both ovaries at the age of 38 because of endometriosis. I have been on premarin 0.45mg since. I only have to take one every 3 days to keep the hot flashes at bay. I tried going off of it twice because even with insurance it was $50 but I thought I was going to die!!!! I could not sleep at all, the hot flashes were horrible, I had no energy to do anything but lay all day on the couch. My life might as well have been over if I didn&#039;t have this drug. I have no side effects on it and I thank God I have it."