Pain
"I had knee surgery.  I can&#039;t tolerate hydrocodone so the Doctor prescribed Nucynta 50 mg. Took two after coming home from the surgery and felt psychotic. It took several hours to get over it.  I&#039;ve since taken one, and just had mild stomach upset.  From the comments posted here, it seems you need to take it for a period of time before it starts working well. "