Depression
"I&#039;ve been on 75/mg of sertraline (generic version of Zoloft) for 5 years.  It has helped a great deal with my depression, anxiety, and compulsive negative thoughts.  I&#039;ve gotten off of it twice; I find that I don&#039;t have withdrawal symptoms if I go off it gradually.  The side effects I&#039;ve had are a decrease in sex drive (which comes back once I stop taking it) and a general feeling of apathy.  It doesn&#039;t make me happy, it just makes me not so sad and much less obsessive.  I do, however, feel I have lost a lot of creativity and motivation.  Other than the apathy and lack of a sex drive, it works extremely well at stopping the depression and anxiety."