"I started taking Kadian about a year ago for spinal stenousis. I was taking 30mg once a day. After a fall, they increased it to 2 a day. It works wonderfully for me. If I miss a day (and I do occasionally if I am not hurting) I pay for it the next day. It seems to leave my body fast so I try to take it even if I am feeling no pain now. I take Lortab 7.5 twice a day in between the Kadian but only as needed. I went today for my 2nd epidural. I hope this works."