Constipation
"I am a 87 yr old with increasing diarrhea for the last few years. I
Was diagnosed about a year ago with possible IBS. Dr. gave Rx for Lenzess which caused severe diarrhea. So only took occasionally then 
began taking regularly about 6 months ago  as prescribed.     Had response within an hour     With diarrhea 6 to 8 episodes
For next 3 to 4 hours. It seems      to work fine, but did not produce a normal BM. Because the diarrhea every day was so disruptive.The Dr.changed the  Rx to every other 
day and still had good results.
Changed  time Rx taken to 30 min b4 the evening meal . Rx seem take longer to work but is a lot less disruptive to my day.Things may never return to normal, but they are a lot better with Lenzess!"