Insomnia
"It it true this medicine can make depression worse in people who are pre disposed to depression?  This is in the brain serotonin is converted into melatonin? The brain has a feed back sensing mechanism: if one takes melatonin tablet the normal level of melatonin present at the receptors goes up , the brain senses this and responds by decreasing serotonin production! I think this drug can be useful for jet lag for those who are not pre disposed to anxiety and depression! I&#039;m pre disposed and I tried it once and felt hopeless the next day! Also did not help sleep! Be careful with melatonin if depression and anxiety are present or are in remission! One can try it and see how they feel!"