Depression
"I take 300 mg effexor am and 15 mg mirtazapine pm just before I go to sleep. This combination has worked very well for me and the only side effect I really have is a bit of dry mouth but that&#039;s probably exacerbated by smoking. For me, they counteract each others side effects at these dosages cause at 225mg effexor and 30mg mirtazapine I had an insatiable appetite at night time!"