Depression
"Like others, I have had good success with Ultracet (Tramadol with Acetaminophen) for pain, GAD and depression. A few weaknesses are 50% of the time I get a small headache. I experience tiredness/fatigue in the morning and lastly, there is the loss of well being when the drug wears off. This is part of the &quot;dependency&quot; (not addiction) that the user has to beware of.
But the drug takes the edge off pain, blows away depression for a bit and reduces anxiety. 
It&#039;s a balance of taking it when I need to but not all the time. It works for me."