Pain
"My Rx 5/325. I had bilateral total knee replacement 12 weeks ago. Taking this totally helped me make it through this recovery period so far. I now take less than one a day and try to use Ibuprofen instead.  My side-effects did not outweigh the benefits, but as you can see from reading the reviews, everyone has a different reaction. Mine are: constipation, so I took a laxative or suppository, slow reaction time, be extremely careful if you have to drive, if you can avoid driving, impaired/cloudy thinking, restlessness. When I go back to my desk job, I can take this during the day, but if you take at night, you may not sleep well. I plan to continue to taper off and use only when pain level above 5. Ibuprofen nighttime works better for sleep."