Constipation
"The first time I used this, it worked perfectly. I was severely constipated and took a few of these (I think maybe 3-4) and had a BM within about 7 hours. 
Second time I used them, it was horrible. I was not as severely constipated, so I took 2 of these at 8 am. Nothing happened all day. I did have a bit of crampy-colicky pain and nausea though (this should have been a warning to me). I was desperate in the evening (8 pm) so I took 3 more. Within about 30 minutes, I was having extreme crampy-colicky pain and nausea. I then had extreme explosive diarrhea and vomiting the rest of the night and was tied to the toliet. In addition, I got chills and body aches from dehydration. It was horrible. I am never taking this medicine again."