Multiple Sclerosis
"I too have MS and have been taking this drug since it came out - about 6 years. Because Provigil is not an amphetamine it doesn&#039;t make you &quot;high&quot;, you just feel like you have energy.  Provigil does not interfere with your normal sleeping pattern, if you take it in the morning.  I feel like my old self when I take it.  I also know now when I do not take it (I&#039;m on 200mg). I can feel the difference, what I thought was depression was actually a lack of energy."