Microscopic polyangiitis
"I was dx with membranoproliferative glomerulonephritis with cryoglobulinemia caused by Sjogren&#039;s syndrome. The tx the first time I was dx was a course of 7 plasmapheresis treatment, prednisone and Rituxan (was effective at the time, no side effects). The next year I had an exacerbation and they decided to give me Rituxan again. A week after I had my first dose I had a severe allergic reaction, which at that time they were not sure it was the Rituxan. I was 4 days in the hospital with severe hives all over the body, swollen face and lips, severe pain in my joints, and high creatinine levels. With high doses of prednisone I was stabilized. For the next tx with Rituxan I had immediate allergic reaction as before and the they had to stop the tx"