Depression
"I am presently in hospital and have been put on Seroquel XR.  As previously commented, the low dosages cause lethargy and sleepiness.  However, I am not nearly as suicidal as I was, I have hope for the future and have not been on for more than a few days.  I am optimistic that once I have reached the proper dosage that I will once again enjoy life as I once did.  Paxil, Effexor and a number of other antidepressants worsened by symptoms over time and/or never did do much for the depressive symptoms in the first place.  This medicine is worth trying if you are extremely depressed or suicidal."