Not Listed / Othe
"Since the 1990s, successful research has been done on buprenorphine for severe depression. I started taking buprenorphine tablets in January for depression At first I needed 1 mg. per day to immediately lift depression. Now I need 2 mg., which has worked well for the past 2 months or so. Buprenorphine for depression makes sense since opiates affect  endorphin receptors. There is no euphoria, except at the beginning. There is no urge to take more than prescribed. I am just much less likely to spiral into despair, no matter what happens. Difficult to get for this purpose--I get it from a pain specialist.  Side effect: constipation."