Bipolar Disorde
"Been on it for about 1 1/2 years for insomnia and mood swings (bipolar 2) Tried a few other drugs but this one works best.  I have gained weight but I am a calmer, happier person on it.  My sleep schedule has settled over time.  Initially I slept too much (10 + hrs) or was tired during day.  Settled finally on 2 generic Seroquel XR50&#039;s about 3-4 hrs before bed and that works pretty good for me.  Don&#039;t know why it takes that long to kick in but it works so I don&#039;t care about why."