Major Depressive Disorde
"Have had a good experience overall with this medication, with an improvement in general symptoms(major depressive disorder). Although I have had nightmares, passing peripheral edema plus unexplained 10 point increase in blood pressure, as side effects. These have been much less and more tolerable than the side effects of the other medications I have used, as listed next.  I have also used cymbalta, effexor, allegron and valdoxin (in order of my opinion of there effectiveness) with cymbalta/valdoxin in combination for a period (over 18 months). I have also undergone ECT. If I had this information when I started I would have chosen this medication as a starting point."