Restless Legs Syndrome
"I&#039;ve been taking carbidopa/Levidopa (generic for Sinemet) for almost 20 years.  No side effects. However, timing is the key. I try to eat dinner very early around 5 o&#039;clock, so the food is totally digested by 11 -12 o&#039;clock midnight. 
Otherwise it could take a long time to feel results, especially if you&#039;ve eaten a lot of protein or fatty foods.  It even states in the &quot;fine print&quot; of this drug that it&#039;s effectiveness is determined by how much protein you eat. 
I take one 25/100mg Carbidopa/Levidopa(CL) at 9:30 pm PLUS one 25/100 and one 50/200mg of CL after 11:00 pm.  
My doc also prescribed half of a 10mg Flexeril to take before bed.  It&#039;s &quot;knocks me out&quot; and I SLEEP!!"