Bipolar Disorde
"I am shocked to read the high amount of mg&#039;s that people are being started on. Every review I have read about Depakote it&#039;s been mainly 1000mg also 500mg. That just blows my mind! With any medicine you have to be eased into things and adjust from there! I began with 250mg, my Doctor told me that after a few weeks I could adjust it to taking 2 doses (500mg). Just to play around with it to see if I in fact needed to go higher. So I did, when changed to 500mg it made me crazy, nutty, mean and intolerable. I backed off and on 250mg again. I have been normal and perfectly stable ever since. I have yet to read a person taking the lowest dosage as a starting point. Start slow and work your way up (if needed). This medicine has been a lifesaver!"