Acne
"I&#039;ve been on this medicine off and on for almost a year now. After I am on it for a few weeks, my joints start to hurt really bad. I think it is because of the diuretic nature of the drug. It doesn&#039;t stop the black heads. It also makes me get up in the night to pee. My Dermatologist says he has never heard of the joint pain being a problem and refused to believe its the spironolactone causing it. But after starting and stopping the medicine three times, I am sure it&#039;s the cause."