Depression
"Weight loss: I lost 21lbs in 4 months:

Better mood=Less appetite=More exercise

Lost craving to carbs. Instead, crave protein. Hike and swim every other day.

Sex drive went down,  not to zero though. Maybe from 8 to 3. (Male) but feeling so much better overall. Wellbeing without sex. Weird but possible.

Once daily 50mg. Welcome to the new me. This is the first antidepressant I ever took. In summary, feel happier and lost 21lbs (from 221 to 200).  More productive at work. Self employed, lost money to depression. Now much better, back to the rat race and loving it. Btw Tramadol metabolises better in some people based on ancestry, so I read. It works for me (Sicilian descent). *Note: most doctors are reluctant to prescribe tram for depression"