Bipolar Disorde
"I am bipolar 1, and take 400mg per day of quetiapine XR. I take this in combination with 200mg of lamotrigine. This combination is highly effective.

The XR version of quetiapine is far superior to the immediate release version. Side effects are lessened with XR. There is some weight gain I am experiencing however I am controling, and even losing the weight, with a strict diet and daily, strenuous exercise with weights. If you do not exercise and eat right on this medication there is a strong chance there will be very noticeable weight gain. That said, quetiapine XR is highly effective at stopping acute mania (in larger doses), and maintaining a baseline mood at my current dosage. I recommend trying this medication for controlling mania"