Ulcerative Colitis, Active
"Rowasa is helpful for administering mesalamine to the rectum and lower portion of the colon; my ulcerative colitis is particularly active there (and the Asacol I take is gone before it gets that far).  It is a good complement (for me) to the Asacol and prevents the blood that otherwise often shows up in my stool.

It is rather messy though.  Administering it is a hassle, it tends to drip.

They can give you mild cramps, however these go away if you lie on your left side for a few minutes to allow the medicine to flow into and coat the lower colon (this works fine for me, as I use it before bed)."