Acne
"I am a physician and tried really everything on my acne, which last now for 24 years. It started during puberty and has been hormonal since then. I have been once put on anti-androgen medication, which was quiet bad considering me being a very young women. But since than nothing helped. Spironolactone was well known to me as diuretic, but not as acne medication (off-label use). But I gave it a try, was quiet concerned about the potassium retention, but what do I have to say: Acne almost gone, no water retention before my menstrual bleeding (gained always about 2-3 kg) and something I would not have thought: no further cramps in my legs, which sometimes woke me up at night. I am very happy about taking Spironolactone."