Acne
"I was terrified to use epiduo after reading the reviews but once I realized I had to buffer it, it seemed much more approachable. If you&#039;re not used to using retinoids, don&#039;t put this directly on your face and don&#039;t use it every night. I took a pretty conservative approach and mostly been able to minimize pain/flaking. 

Here&#039;s what I do:
-Wash my face with a gentle cleanser (I use Aveeno Positively Radiant)
-Put on some cerave moisturizer
-Wait 20 minutes
-Put on the epiduo forte

I only do this at night, once every 2-3 days. If I feel my skin getting irritated, I&#039;ll stop using the epiduo till it gets back to normal. Don&#039;t muck around with your skin! If it&#039;s irritated and awful, no reason to torture yourself and use the epiduo every night just use it every couple of nights"