Migraine Prevention
"Before Depakote, I&#039;ve tried vitamin B2, verapamil, and Topamax, but for one reason or another none of them have worked. About 6 months ago, my doctor started me on Depakote. Once I started using it, my daily headaches became a lot more tolerable, but haven&#039;t gone away completely, and my severe migraines are at about once a month. However, like many others, there was a noticeable weight gain--about 20 pounds--soon after I started, and it&#039;s been pretty steady since. I&#039;ve also had a bout of depression recently, but it&#039;s hard to tell how that&#039;s related to the medicine because it isn&#039;t my first time. As of right now, I&#039;m not sure the minor benefits are worth the side effects."