Acne
"I was very sceptical about using differin cream as I had done a lot of reading and has obviously read about the dreaded initial breakout! A side note, I am also on lymecycline 408mg (tetracycline is the same) and I&#039;m on lucette bc. When I first started using it I left it on for an hour, to see how my skin reacted, then washed it off. I have been leaving it on overnight now for about a week and a half. Yes, I have broken out. Any worse than usual? No. In fact the breakouts healed, were less aggressive and red. Currently the only side effect I&#039;ve got is the corners of my mouth are a bit sore and dry. My skin is very soft where I use the cream. My advice, start slow! And use it so sparingly!! Literally the tiniest bit. I am pleased so far. :)"