Irritable Bowel Syndrome
"I have IBS with constipation.  My GI started me on Amitiza, which worked great for 3 or 4 months, then I started having constipation again, but without the extreme cramps.  He gave me Linzess 145, which also worked great for a couple months, then not so much.  I had a colonoscopy and upper GI, which all came back normal except for an irritated stomach.  I&#039;ve been on Linzess 290 now for several months, and it still works, but the way it works affects my daily plans.  It may just work too good.  I have very watery movements about 3 times every morning, and because of this I can&#039;t leave the house before noon.  I haven&#039;t had a solid stool for months.  Good thing I&#039;m a stay at home mom!  Taking this every other day might make things better."