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After five seasons, 13 Emmy noms and two wins for lead actor Jim Parsons, Chuck Lorre's enduring Thursday night hit has production -- and geek-friendship comedy -- down to a science.

ON THE SET: Kaley Cuoco & Johnny Galecki
David Strick
"The Big Bang Theory"

There's an air of excitement in nerd paradise, the set on the Warner Bros. lot in Burbank, where the cast and crew of CBS' ensemble comedy The Big Bang Theory, hard at work on the next to last episode of the year, have only a week left before wrapping their fifth season.

On this morning, on-screen roommates Johnny Galecki and Jim Parsons, and their dork-posse Simon Helberg and Kunal Nayyar are filming a scene in which they're being fitted for tuxedos for Howard's (Helberg) marriage to Bernadette (Melissa Rauch); co-stars Kaley Cuoco, Rauch and Mayim Bialik are in hair and makeup.

After a few takes, exec producers Chuck Lorre, Bill Prady and Steve Molaro, and others, huddle behind a wall of monitors, tweaking the dialogue to include references to science — and the Flash.

PHOTOS: Behind the Scenes: 'The Big Bang Theory'

"On a show like this, because the language is so specific, you have to know it perfectly, because if you don't, it'll take five to eight takes to get it right," Nayyar says of the script fix, which references the speed at which Howard's Soyuz rocket could potentially plummet to Earth.

Between takes, the guys connect in the same fashion on their onscreen family, joking about anything pop culture, including Kim Kardashian's recent flour-bombing, all while Parsons as germaphobe Sheldon is clad in red long johns so as to avoid the microbes that (naturally!) lurk in a rental tux.

"Two weeks ago, I was in a French maid costume and that I talked them down from," Parsons says. "They wanted me in the Princess Leia slave uniform and a bikini. I said I'd need six months' warning and a personal trainer."

Meanwhile, director Mark Cendrowski, who has helmed nearly every episode, says the cast and crew has production down to a fine science. "We established a good shorthand early on that has helped carry out through the five years and made our days go quicker, and shorter," he notes. "With Chuck having to do several shows, we often get a truncated rehearsal time. I've always compared it to playing with an all-star team: You just roll the ball out and sometimes say, 'Go.' "

Check out The Hollywood Reporter's Big Bang Theory behind the scenes gallery by clicking here.

Email: Lesley.Goldberg@thr.com; Twitter: @Snoodit