Отключить xcache?
Примерно так:
set $php_admin_value "xcache.cacher=Off";
set $php_admin_value "$php_admin_value \n xcache.stat=Off";
set $php_admin_value "$php_admin_value \n xcache.optimizer Off";
fastcgi_param  PHP_ADMIN_VALUE $php_admin_value;

Примерно так:
set $php_admin_value "xcache.cacher=Off";
set $php_admin_value "$php_admin_value \n xcache.stat=Off";
set $php_admin_value "$php_admin_value \n xcache.optimizer Off";
fastcgi_param  PHP_ADMIN_VALUE $php_admin_value;
