(CNN) -- A bus hopped a highway median and crashed into a pickup truck before being broadsided by an 18-wheeler, Arkansas police said, killing the pickup driver and two bus riders.

Two passengers were found dead inside the bus, said Arkansas State Police.

Forty people were hurt in Sunday night's crash, which shut down a 13-mile stretch of Interstate-40 east of Forrest City, Arkansas, said state police spokesman Bill Sadler.

The bus was westbound en route from Chicago, Illinois, to Dallas, Texas.

The driver of the pickup truck -- identified as 30-year-old Danny Okurily of Hot Springs, Arkansas -- died at the scene of the accident, Sadler said. Bus driver Felix Tapia, 28, of Brownsville, Texas, and tractor-trailer driver David Rice, 45, of Mars Hill, North Carolina, suffered minor injuries, according to The Associated Press.

Two passengers were also found dead inside the bus, he said. Their names were not released because authorities have not yet notified relatives, Sadler said.

Several dozen injured passengers were taken to hospitals in Forrest City, Memphis and West Memphis, said police.

The bus, which listed 44 passengers on its manifest, was owned and operated by the Tornado Bus Line, which is based in Dallas, Texas, Sadler said.

The crash happened just after 10 p.m. CT about 10 miles east of Forrest City and about 40 miles west of Memphis, Tennessee, Sadler said. E-mail to a friend
Who reports that there was a 3-vehicle crash? Who was injured? Who was killed in the crash? What number of people where killed? Where was the 3-vehicle crash? What caused the traffic accident? What vehicles were involved in the accident? What were the ages of the victims? Who was injured in the crash? What highway is closed? Was anyone injured? Where did the bus cross What road was closed? Are any roads closed as a result? who says killed? Who were the 3 killed?
Arkansas police Forty people were hurt Danny Okurily Two passengers Interstate-40 east of Forrest City, Arkansas, bus hopped a highway median and crashed into a pickup truck 18-wheeler, 30-year-old passengers Interstate-40 Forty people highway median 13-mile stretch of Interstate-40 east of Forrest City, Arkansas, 13-mile stretch of Interstate-40 east of Forrest City, Arkansas police killing the pickup driver and two bus riders.
question: Who reports that there was a 3-vehicle crash?, answer: Arkansas police | question: Who was injured?, answer: Forty people were hurt | question: Who was killed in the crash?, answer: Danny Okurily | question: What number of people where killed?, answer: Two passengers | question: Where was the 3-vehicle crash?, answer: Interstate-40 east of Forrest City, Arkansas, | question: What caused the traffic accident?, answer: bus hopped a highway median and crashed into a pickup truck | question: What vehicles were involved in the accident?, answer: 18-wheeler, | question: What were the ages of the victims?, answer: 30-year-old | question: Who was injured in the crash?, answer: passengers | question: What highway is closed?, answer: Interstate-40 | question: Was anyone injured?, answer: Forty people | question: Where did the bus cross, answer: highway median | question: What road was closed?, answer: 13-mile stretch of Interstate-40 east of Forrest City, Arkansas, | question: Are any roads closed as a result?, answer: 13-mile stretch of Interstate-40 east of Forrest City, | question: who says killed?, answer: Arkansas police | question: Who were the 3 killed?, answer: killing the pickup driver and two bus riders.