Context: Serotonin is a neuromodulator involved in regulation of mood and behavior. Development in the limbic system plays an important role in determining rewards and punishments and processing emotional experience and social information. Changes in the levels of the neurotransmitters dopamine and serotonin in the limbic system make adolescents more emotional and more responsive to rewards and stress. The corresponding increase in emotional variability also can increase adolescents' vulnerability. The effect of serotonin is not limited to the limbic system: Several serotonin receptors have their gene expression change dramatically during adolescence, particularly in the human frontal and prefrontal cortex .

Question: Which neuromodulator is involved in regulation of mood and behavior?
Answer: Serotonin

Question: Are the effects of serotonin limited to the limbic system?
Answer: not

Question: Serotonin is a neuromodulator that is involved in regulation of what?
Answer: mood and behavior

Question: Which system in the brain determines rewards and punishments, emotional experiences, and social information?
Answer: limbic

Question: Which two neurotransmitters cause adolescents to be more emotional and more responsive to rewards and stresses?
Answer: dopamine and serotonin