Context: Tuberculosis has been present in humans since antiquity. The earliest unambiguous detection of M. tuberculosis involves evidence of the disease in the remains of bison in Wyoming dated to around 17,000 years ago. However, whether tuberculosis originated in bovines, then was transferred to humans, or whether it diverged from a common ancestor, is currently unclear. A comparison of the genes of M. tuberculosis complex (MTBC) in humans to MTBC in animals suggests humans did not acquire MTBC from animals during animal domestication, as was previously believed. Both strains of the tuberculosis bacteria share a common ancestor, which could have infected humans as early as the Neolithic Revolution.

Question: What animal was found with 17,000-year-old damage from tuberculosis?
Answer: bison

Question: What does MTBC stand for?
Answer: M. tuberculosis complex

Question: During what time period do some scientist believe the first human could have contracted TB from an ancestor they shared with animals?
Answer: Neolithic Revolution

Question: In which U.S. state was the oldest definitive evidence of TB found?
Answer: Wyoming

Question: When was Wyoming discovered?
Answer: Unanswerable

Question: Which gene was concluded to come from animals?
Answer: Unanswerable

Question: What period did the bison live in?
Answer: Unanswerable

Question: What did animals get TB from?
Answer: Unanswerable

Question: What species have we definitively traced the origin of TB to?
Answer: Unanswerable