Context: Duplications play a major role in shaping the genome. Duplication may range from extension of short tandem repeats, to duplication of a cluster of genes, and all the way to duplication of entire chromosomes or even entire genomes. Such duplications are probably fundamental to the creation of genetic novelty.

Question: What type of generation of genetic material has a big part in making the genome what it is?
Answer: Duplications

Question: What is a possible product of duplications?
Answer: genetic novelty

Question: What role does genetic novelty play in the genome?
Answer: Unanswerable

Question: What is the first range of genetic novelty?
Answer: Unanswerable

Question: What are gene clusters a large part of?
Answer: Unanswerable

Question: How far can genetic novelty go?
Answer: Unanswerable

Question: What is the first example of genetic novelty?
Answer: Unanswerable