Context: Shift-work or chronic jet-lag have profound consequences on circadian and metabolic events in the body. Animals that are forced to eat during their resting period show increased body mass and altered expression of clock and metabolic genes.[medical citation needed] In humans, shift-work that favors irregular eating times is associated with altered insulin sensitivity and higher body mass. Shift-work also leads to increased metabolic risks for cardio-metabolic syndrome, hypertension, inflammation.

Question: What effect does jet-lag and shift-work have on the human body?
Answer: profound consequences

Question: Animals that eat during resting periods show what body increase?
Answer: body mass

Question: How does irregular eating during shift-work effect insulin?
Answer: insulin sensitivity

Question: Besides insulin sensitivity, what other effect does shift-work have on the body?
Answer: higher body mass

Question: What type of work can lead to heart, hypertension and inflammation?
Answer: Shift-work

Question: What does shift work have little effect on?
Answer: Unanswerable

Question: What causes animals to have decreased body mass?
Answer: Unanswerable

Question: What decreases insulin sensativity?
Answer: Unanswerable

Question: What kind of work leads to lower body mass?
Answer: Unanswerable