LOS ANGELES, California (CNN) -- The latest 3-D animated movie involves the possible extinction of the human race and features a mad scientist with the head of a cockroach, a prehistoric half-ape/half-fish, a 50-foot-tall woman (OK, 49-foot-11), and a blue brainless blob named B.O.B. The Missing Link, Ginormica, the blue blob B.O.B. and Insectosaurus dominate "Monsters vs. Aliens." And they're the good guys. Reese Witherspoon leads the cast of "Monsters vs. Aliens," providing the voice of Susan, who is hit by a glowing meteorite on her wedding day. Before long she's grown into the biggest thing around. The short-statured Oscar winner relished the chance to play not only a giant, but also a role model.
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"Monsters vs. Aliens" is about motley group of misfits who team up to defeat alien
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Monsters are led by almost 50-foot woman, voiced by Reese Witherspoon
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Witherspoon says she hopes character can be role model for girls
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Other actors lending talents: Seth Rogen, Kiefer Sutherland, Will Arnett
It was a welcome change of pace for @placeholder, who recorded his voice tracks for "Monsters" while he was filming the uber-intense "24."