Los Angeles (CNN) -- Jurors in the involuntary manslaughter trial of Michael Jackson's doctor will hear closing arguments from the prosecution and defense Thursday, with deliberations on Dr. Conrad Murray's fate expected to begin late Thursday or Friday. It follows 22 days of testimony from several of Murray's girlfriends and patients, Jackson employees, paramedics and emergency room doctors, investigators and medical experts. Jackson's mother will sit on one side of the courtroom, while Murray's mother is likely to be seated on the other end Thursday as the seven men and five women on the jury listen to each side sum up their case.
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Jurors have two theories of guilt to consider for Dr. Conrad Murray
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Prosecutors say Murray's use of propofol for Jackson's insomnia was criminally negligent
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The defense contends Jackson gave himself the fatal overdose
He was so desperate for sleep, and afraid his comeback concerts would be canceled without it, that he injected himself while @placeholder was not watching, the defense argues.