Context: Death from laughter is a rare form of death, usually resulting from cardiac arrest or asphyxiation, caused by a fit of laughter. Instances of death by laughter have been recorded from the times of ancient Greece to the modern day.
 Question: can you have a heart attack from laughing Context: To shotgun a beverage, a small hole is punched in the side of the can, close to the bottom. In order to prevent the liquid from spilling out while the cut is made, the can is held horizontally, tilted slightly, and the hole is made in the resulting air pocket. The hole can be made with any sharp object. Typically, a key, bottle opener, pen, knife, other sharp instrument is used. The drinker then places their mouth over the hole while rotating the can straight up. When the can's tab is pulled, the liquid will quickly drain through the hole into the drinker's mouth.
 Question: do you shake a beer before shotgunning it Context: The main function of the blood--brain barrier is to protect the brain and keep it isolated from harmful toxins that are potentially in the blood stream. It accomplishes this because of its structure, as is usual in the body that structure defines its function. The tight junctions between the endothelial cells prevent large molecules as well as many ions from passing between the junction spaces. This forces molecules to go through the endothelial cells in order to enter the brain tissue, meaning that they must pass through the cell membranes of the endothelial cells. Because of this, the only molecules that are easily able to transverse the blood--brain barrier are ones that are very lipid-soluble. These are not the only molecules that can transverse the blood--brain barrier; glucose, oxygen and carbon dioxide are not lipid-soluble but are actively transported across the barrier, to support normal cellular function of the brain. The fact that molecules have to fully transverse the endothelial cells makes them a perfect barricade to unspecified particles from entering the brain, working to protect the brain at all costs. Also, because most molecules are transported across the barrier, it does a very effective job of maintaining homeostasis for the most vital organ of the human body.
 Question: can lipid soluble drugs cross blood brain barrier Context: When synthesizing new DNA, DNA polymerase can add free nucleotides only to the 3' end of the newly forming strand. This results in elongation of the newly forming strand in a 5'--3' direction. No known DNA polymerase is able to begin a new chain (de novo); it can only add a nucleotide onto a pre-existing 3'-OH group, and therefore needs a primer at which it can add the first nucleotide. Primers consist of RNA or DNA bases (or both). In DNA replication, the first two bases are always RNA, and are synthesized by another enzyme called primase. Helicase and topoisomerase II are required to unwind DNA from a double-strand structure to a single-strand structure to facilitate replication of each strand consistent with the semiconservative model of DNA replication.
 Question: can a dna polymerase initiate new strand of nucleic acid independently
Yes
No
Yes
No