Clinical study on rTMS facilitating motor functions recovery under the guidance of fMRI in cerebral infarction patients
【Objective】To explore the therapeutic effects of repetitive transcranial magnetic stimulation(rTMS) guided by fMRI on rehabilitation of motor functions in patients after cerebral infarction.【Methods】fifty patients(28 males and 22 females with acute cerebral infarction of right corona radiata were selected. They were randomly allocated into 5 groups(10 in each group). All subjects accepted the same basic therapy. Hotor function of the affeced hand of patient in the treatment groups(group A-D) was evaluated with Fugl-Meyer scale(FMA) before and after r7MS and 90 days later. General status of neurological deficiency and activities of daily living of all patients were assessed with National Institute of Health stroke scale(NIHSS) and Barthel index(BI).【Results】The FMA and BI of all treated groups 14d and 90d after treatment were significantly different as compared with before treatment(P0.05). The NIHSS of90d were significant different as compared with before treatment(P0.05).【Conclusion】Stimulating the contralateral M1 area with rTMS under the guidance of fMRI may improve the hand motor function, recover the neurological deficiency and activity of daily living of the patients with cerebral infarction.