METHODS AND COMPOUNDS FOR LYMPHOMA CELL DETECTION AND ISOLATION
Compositions comprising a purified and/or isolated antibody, humanized antibodies, precipitates and anti-sera that specifically bind to or are otherwise directed against ROR-1 protein. The compositions may be used for detecting ROR-1 in a sample from a subject that is suspected or known to contain cancer cells. The ROR-1 antibodies are especially useful in identifying and treating lymphomas and ademocarcinomas. Vaccines and related methods for protecting a subject against diseases that involve expression of ROR-1 are also provided, as are human anti-sera effective in abrogating interactions between Wnt5a protein and ROR-1 that contribute to the survival of certain cancer cells, such as CLL cells.