Abstract 16912: Angioplasty vs. primary nitinol stent implantation in above knee femoropopliteal occlusive atherosclerotic disease: a meta-analysis of randomized controlled trials
Background: The efficacy and safety of contemporary self-expanding bare metal Nitinol stents (NS) compared to primary Percutaneous Transluminal Angioplasty (PTA) in the treatment of above-knee femoropopliteal atherosclerotic disease is still controversial. Objective: We sought to evaluate the immediate (procedural success) and intermediate (rate of restenosis and target lesion/vessel revascularization (TLR/TVR) at 1 year) clinical outcomes of primary NS implantation versus primary PTA with bailout stenting in the treatment of above-knee femoropopliteal disease by conducting a meta-analysis of the available randomized controlled trials (RCT). Methods: We searched Medline and Cochrane databases from 1990 to 2014. Risk ratios (RR) and 95% confidence intervals (CI) were calculated using random-effects model. Results: Six RCTs with a total of 827 patients (NS = 443, PTA = 384; average age 68.5 years, males = 562, average lesion length = 8.7cm in NS and 7.7cm in PTA) were analyzed on intention to treat basis. T...