Anti-Müllerian Hormone (AMH)
Anti-mullerian hormone (AMH) is a glycoprotein produced by granulosa cells of healthy, growing ovarian follicles in females and its receptors are expressed in oocytes, granulosa, and theca cells. AMH known functions are (1) inhibition of primordial follicular growth from the ovarian reserve, avoiding its premature exhaustion and (2) modulation of follicular development. AMH circulating concentrations are relatively constant during the menstrual/estrous cycle and are repeatable across multiple cycles in women and cattle, thus AMH concentrations can be reliably measured with a single blood sample. Because AMH correlates with the size of the ovarian reserve, it may be used to predict fertility, reproductive longevity and response to ART.