Effect analysis of finasteride and metformin combination therapy of benign prostatic hyperplasia in elderly diabetic
Objective To investigate the effect of finasteride and combination therapy with metformin in elderly diabetic patients with benign prostatic hyperplasia. Methods Seventy-five cases of benign prostatic hyperplasia patients with diabetes mellitus in this group were selected from April 2012 to September 2013 in our hospital, they used finasteride metformin therapy, the clinical results after and before treatment were compared with statistical methods. Results The international prostate symptom score, quality of life score, prostate volume, prostate-specific antigen, residual urine volume, body mass index and triglycerides after treatment were lower than before treatment, the maximum flow rate was higher than before treatment, there were significant difference between after and before treatment(P 0.05). Conclusion Finasteride combined metformin hydrochloride for benign prostatic hyperplasia patients with diabetes have better clinical results, the two drugs with synergistic effect can be used in clinical practice.