NEW MANDELIC ACID DERIVATIVES AND THEIR USE AS THROBIN INHIBITORS
There is provided a compound of formula (I) wherein R<a>, R<1>, R<2>, Y and R<3> have meanings given in the description and pharmaceutically-acceptable derivatives (including prodrugs) thereof, which compounds and derivatives are useful as, or are useful as prodrugs of, competitive inhibitors of trypsin-like proteases, such as thrombin, and thus, in particular, in the treatment of conditions where inhibition of thrombin is required (e.g. thrombosis) or as anticoagulants.