Re: Does Perineural Invasion on Prostate Biopsy Predict Adverse Prostatectomy Outcomes?
Editorial Comment: If a man has a family history of breast cancer, is he at increased risk for prostate cancer? In this brief letter the authors report on the large Swedish family cancer database. For men with a family history of prostate cancer there was a 3.4-fold increase in risk of prostate cancer if the father was affected, and 6.7 if both the father and brothers were affected. Correspondingly the risk was only 1.2 if the mother was diagnosed with breast cancer, 1.07 for an affected sister, and 1.6 when both the mother and sister were diagnosed. It appears that a family history of breast cancer has little or no effect on the risk of a man being diagnosed with prostate cancer, at least in Sweden.