A PHARMACEUTICAL COMPOSITION CONTAINING VITAMIN B12
The invention relates to a pharmaceutical composition for intranasal administration for human subjects comprising vitamin B12 and a pharmaceutically acceptable carrier. According to the invention, vitamin B12 particles are dispersed in a hydrophobic continuous phase as the pharmaceutically acceptable carrier. Such a dispersion of solid vitamin B12 particles (crystals or amorphic) in a hydrophobic continuous phase displays very satisfactory bioavailability. Also, the intense red colour is reduced significantly, making the pharmaceutical composition acceptable for intranasal use.