Effects of aerobic interval and moderate continuous training on erythrocyte rheological property modulated by hypoxic exercise in sedentary men (706.9)
This study investigated how aerobic interval (AIT) and moderate continuous training (MCT) influence hypoxic exercise-mediated erythrocyte aggregability and deformability under various shear conditions in sedentary men. Twenty-four sedentary males were randomized to perform AIT 3-minute intervals at 40% and 80% VO2 peak, n=12) or MCT (sustained 60% VO2 peak, n=12) for 30 minutes/day, 5 days/week for 6 weeks. Erythrocyte aggregability and deformability under various shear conditions were determined by a slit-flow ektacytometer. The results showed that, before exercise training, the 60%VO2max exercise under 12%O2 decreased maximal elongation index (EImax), as well as, increased aggregation index (AI) and shortened aggregation half-time (t1/2) in erythrocytes under shear flow. However, both AIT and MCT diminished erythrocyte EImax and AI, as well as, lengthened erythrocyte t1/2 during the 12%O2 exercise. Accordingly, we conclude that either AIT or MCT effectively improves hemorheological function by decreasing aggregability and increased deformability of erythrocytes during hypoxic exercise in sedentary men.