PHOTODYNAMIC THERAPY FOR CHOROIDAL NEVUS WITH SUBFOVEAL FLUID
To report the efficacy of photodynamic therapy (PDT) for management of choroidal nevus associated with subfoveal fluid.A retrospective chart review of 15 patients with choroidal nevus and associated subfoveal fluid treated with PDT was performed. Standard-fluence PDT was used in all patients and response to treatment was assessed with optical coherence tomography.Complete resolution of subfoveal fluid was achieved in 9 eyes (60%) and partial resolution in 4 eyes (27%); 1 eye (7%) experienced worsening subfoveal fluid, and 1 eye (7%) was stable after PDT. After PDT, visual acuity improved in 8 eyes (53%), was stable in 6 (40%), and worsened in 1 eye (7%). Five patients (33%) required a second session of PDT with a median of 4 months (mean, 9 months; range 2-25 months) between the first and second sessions of PDT.Photodynamic therapy is a safe and effective treatment modality for choroidal nevus with subfoveal fluid. Photodynamic therapy provided satisfactory rates of resolution of subfoveal fluid in 87%, which was complete in 60% and partial in 27%. Further studies could further define the role and limitations of PDT for management of subfoveal fluid from choroidal nevus.