The relevant risk factors for analyzing the occurrence and distribution of cerebral microbleedsin old patients with transient ischemic attack
Objective: To investigate the relevant risk factors for analyzing the occurrence and distribution of cerebral microbleeds(CMB) in old patients with transient ischemic attack(TIA). Materials and Methods: One hundred and eightytwo old patients with TIA diagnosed by physician were collected from September 2013 to July 2015 in our hospital, whose clinical data and MRI data were analyzed by two neurologists and two radiologists respectively. Clinical data included age, gender, clinical symptoms, diagnosis, confounding diseases, IADL score and biochemical test results(such as triglyceride(TG)and high-density lipoprotein(HDL)). MRI data contained the location and distribution of CMB, the degree of lacunar infarction(LI), periventricularhighsignal(PVH) and deep white matter hyperintensities(DWMH). Then the relative risk factors were analysis for the occurrence and distribution of CMB in old patients with TIA. Results: In comparison with CMB(-)group, there were higherage, LI amount, PVH and DWMH grading and lower HDL in CMB(+) group, which had statistical significance(P0.05), but IADL score was not statistical signifi cance(P0.05) in both groups. For the distribution of CMB, there were higher LI and DWMH in diffuse type than cerebral lobe and deep structure type, which had statistical significance(P0.05). but HDL level was not statistical signifi cance(P0.05) among three type groups. The relative risk factors were serious PVH and high TG for cerebral lobe type(OR=7.01)and deep structure type(OR=6.80)respectively, and were serious DWMH and LI amount for diffuse type(OR=9.4; OR= 7.88). Conclusion: The occurrence and distribution of CMB in old patients with TIA are related to age, LI amount, TG, PVH and DWMH grading, which are helpful to the diagnosis and treatment for CMB patients.