PROCESS FOR THE PREPARATION OF FLIBANSERIN INVOLVING NOVEL INTERMEDIATES
The present invention related to process for the preparation of flibanserin involving novel intermediates. 1,3-dihydro-1-(2-bromoethyl)- 3-isopropenyl-2H-benzimidazol-2-one reacts with diethanolamine and converting the obtained dihydroxy compound to 1,3-dihydro- 1-[2-[N-[bis-(2-chloroethyl)amino]ethyl]-3-isopropenyl-2H-benzimidazol-2-one followed by depotection to obtain 1,3-dihydro- 1-[2-[N-bis-(2-chloroethyl)amino]ethyl]-1,2-H-benzimidazol-2-one. This on condensing with m-trifluoromethyl aniline gives flibanserin hydrochloride.