Creating a Platform for Precise Anti-Cancer Medicine
Therapeutic strategies that are based on the individual genetic profile of a patient represent a new frontier of applied cancer research. These strategies are expected to reduce the socio-economic impact of current cancer therapies that are cost-intensive and often ineffective, thus releasing pressure on regional health systems. In this context, tumor-organoids are of special relevance. Tumor-organoids are three-dimensional cellular complexes that are cultivated in vitro from cells that were previously obtained from patient tumors or biopsies. Tumor-organoids have the special property to mirror the key-features of the original patient’s tumor. Thus, Tumor-organoids represent an ideal tool to develop patient-specific therapies by performing drug-screenings. _x000D_
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The PreCanMed project aims to strengthen the collaboration between Italian and Austrian institutions that perform genetic, clinical and biotechnology research in order to establish a common competence-platform for the generation, cultivation and storage (Live-biobank) of numerous patient-derived Tumor-organoids. Tumor-organoids and know-how will be freely accessible, thus making this cutting edge technology accessible to the academic, translational, clinical and pharmaceutical research and development sector.