AN IMPROVED PROCESS FOR THE PREPARATION OF 3-[2-[4-(6-FLUORO-1,2-BENZISOXAZOL-3-YL)-1-PIPERIDINYL]ETHYL]-6,7,8,9-TETRAHYDIO-9-HYDROXY-2-METHYL-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE.
A process for the preparation of paliperidone from the hydrolysis of paliperidone palmitate in the presence of an acid in a solvent.