METHOD AND COMPOSITION FOR THE TREATMENT OF THROMBOSIS IN A MAMMAL
A composition comprising a plurality of microcapsules suitable for parenteral injection into a mammal comprising a streptokinase-containing core, and a semi-permeable biocompatible layer surrounding the core permitting controlled release of at least a portion of the streptokinase. A method of reducing the time required for reperfusion of an artery containing a thrombus and a method to reduce the standard dosage requirement of a plasminogen activator in a mammal comprising intravenous injection of a composition comprising a plurality of microcapsules comprising a plasminogen activator core surrounded by a controlled release semi-permeable layer.