Neuroendocrine tumor treatment
A method for treating a neuroendocrine tumor, particularly pancreatic neuroendocrine tumor, comprising administering to a subject in need thereof a therapeutically effective amount of a compound of formula (I) or a pharmaceutically acceptable salt thereof, alone or in combination with at least one therapeutic agent, wherein said neuroendocrine tumor is resistant or refractory to treatment with at least one mTOR inhibitor; uses of said compounds for the preparation of a medicament for use in the treatment of a neuroendocrine tumor resistant or refractory to treatment with at least one mTOR inhibitor, uses of said compound for treating said disease; and related pharmaceutical compositions and pharmaceutical package thereof.