Wilhelm Olivier Leube
16 May 1922
['10 May 2008', '29 June 1954', '28 March 1949', '18 February 1982', '29 June 2002', '24 February 1964', '27 July 1960', '28 February 1921', '2 April 1973', '12 February 2002', '12 March 2013', '30 March 1986', '26 May 1976', '6 July 2002', '24 January 1940', '16 July 2007', '13 February 1953', '28 October 1932', '26 April 1920', '2 March 1982', '26 January 1930', '6 October 1947', '1 January 2008', '19 March 1987', '21 October 1977', '13 January 2008', '20 October 1898', '18 June 1983', '9 April 1915', '19 May 1949', '24 November 1950', '23 May 2006', '16 May 1959', '24 October 1998', '15 February 1960', '23 April 1996', '16 March 1963', '20 January 1991', '10 July 1953', '31 December 1954', '22 March 1993', '5 October 1874', '13 March 1938', '27 July 2013', '8 April 1968', '2 May 2008', '14 July 1973', '27 November 1983', '17 April 1972', '24 October 1969', '14 April 1991', '31 January 1907', '26 January 1998', '9 January 2014', '30 October 1914', '16 March 1927', '3 August 2010', '8 March 2007', '21 May 1944', '18 May 1980', '31 July 1942', '28 June 2012', '14 September 1995', '2 September 1984', '12 November 1946', '9 June 1938', '28 April 1947', '13 December 1960', '19 October 1945', '28 December 1969', '29 March 1956', '8 June 1926', '15 January 1899', '7 May 1963', '3 November 1975', '19 November 2008', '23 October 1987', '22 March 2011', '25 November 1963', '21 July 1922', '8 December 1976', '30 June 1993', '24 June 1982', '18 March 1968', '21 September 1936', '29 April 1940', '21 March 1939', '9 April 2008', '8 January 1998', '1 July 2010', '7 April 1992', '14 January 1952', '31 October 1975', '19 June 2009', '15 March 1957', '2 May 1997', '24 March 1977', '26 September 1989', '17 February 1951']
Wilhelm Olivier Leube
Wilhelm Olivier Leube (14 September 1842 – 16 May 1922) was a German internist born in Ulm. He studied medicine in Tübingen, Zurich, Berlin and Munich, and from 1868 worked as an assistant at the medical clinic in Erlangen. In 1872, at the University of Jena, he became a professor of pathology and special therapy, as well as director of the medical clinic. At Jena, one of his assistants was noted physician Ottomar Rosenbach (1851–1907). Afterwards he was a professor at the Universities of Erlangen (1874–1885) and Würzburg, where in 1895/96 he served as university rector. Wilhelm Leube is remembered for his work with gastric and intestinal disorders that included pioneer research of "nervous dyspepsia". He believed that gastric irritation was often caused by the effects of food on the sensory nerves of the stomach, and performed extensive studies on digestion. In 1871 he introduced a procedure known as intubation in order to retrieve contents of the stomach for analysis. Later he introduced "test meals" of different types of food, which would be served to patients, and afterwards retrieved via Leube's "gastric tube" at scheduled times. Through these procedures, Leube researched the degree of digestion of the test meal, as well as the quantity and concentration of acid and pepsin in the patients' stomach. With physiologist Isidor Rosenthal (1836–1915), he developed the Leube-Rosenthalsche Fleischsolution (Leube-Rosenthal meat solution). Among Leube's written works was an influential treatise on gastro-enterological diseases called "Die Krankheiten des Magens und Darms" (1875), that was included in Hugo Wilhelm von Ziemssen's "Handbuch der speciellen Pathologie und Therapie". Leube died on 16 May 1922 at Montfort Castle on Lake Constance.