{"content":[{"text":"NCI Patient-Derived Models Repository (PDMR) Material Request Procedures","bbox":{"left":0.106275,"top":0.046726,"width":0.6225269999999999,"height":0.016778999999999995}},{"text":"Effective Date:","bbox":{"left":0.106275,"top":0.072407,"width":0.11927,"height":0.016779000000000002}},{"text":"12/9/2020","bbox":{"left":0.253725,"top":0.072407,"width":0.07960800000000001,"height":0.016779000000000002}},{"text":"Page 1 of 5","bbox":{"left":0.711471,"top":0.072407,"width":0.0888230000000001,"height":0.016779000000000002}},{"text":"NCI Patient-Derived Models Repository (PDMR) Material Request Procedures \n NCI PATIENT-DERIVED MODELS REPOSITORY (PDMR) MATERIAL REQUEST PROCEDURES ...................... 1 \n The following items are required to receive materials: ........................................................................... 1 \n Specimen types that may be requested: ................................................................................................... 2 \n MTA Information .................................................................................................................................... 3 \n PDMR Request Review Criteria ............................................................................................................. 3 \n General Shipping and Handling Information .......................................................................................... 4 \n Distribution Costs (excluding shipping) ................................................................................................. 5 \n Contact Information ................................................................................................................................ 5","bbox":{"left":0.088235,"top":0.113392,"width":0.8227460000000001,"height":0.20920299999999997}},{"text":"The following items are required to receive materials: \n 1. Fill out a PDMR Model Request Form. \n a. Currently only requests from Domestic sites, until further notice \n b. Provide a brief description of the research plan for the requested material(s)","bbox":{"left":0.088235,"top":0.354529,"width":0.741235,"height":0.091779}},{"text":"c. All applicants should have a clear plan for banking PDX and cell culture material for \n their planned studies. PDMR SOPs <Link: https://pdmr.cancer.gov/sops/default.htm> \n include workflow diagrams for PDX tissue/cell line receipt and banking as a guidance \n if needed. \n d. If requesting CAF cultures, be sure the research plan includes details on expected use \n and potential novel contributions to the field. Also ensure you state that you \n understand these models are only guaranteed for 3 passages of growth, though \n additional population doublings and subcultures are possible. \n e. Intramural investigators (MD campuses) – leave the FedEx and Payment Information \n blank \n Send the Material Transfer Agreement (MTA) with all requested models included in the \n appropriate Appendix and the requesting site’s authorizing official signature affixed. Once \n the request has been approved by the review committee, NCI will route for signatures by the \n NCI authorizing official. Modifications to NCI’s MTA will not be considered. \n a. Intramural Investigators: Use the designated MTA for Intramural Investigators","bbox":{"left":0.176471,"top":0.458316,"width":0.7341930000000001,"height":0.29102199999999995}},{"text":"2.","bbox":{"left":0.147059,"top":0.655286,"width":0.014705999999999997,"height":0.01677899999999999}}],"images_bbox":[{"left":0.088235,"top":0.918182,"width":0.390278,"height":0.03628},{"left":0.695098,"top":0.909091,"width":0.209314,"height":0.045453}],"images_bbox_not_text_overlap":[{"left":0.088235,"top":0.918182,"width":0.390278,"height":0.03628},{"left":0.695098,"top":0.909091,"width":0.209314,"height":0.045453}]}