التقييس لدول مجلس التعاون لدول الخليج العربية  هيئة  
GCC STANDARDIZATION ORGANIZATION (GSO)  
 
 
مشروع تحديث لائحةنهائي  
Final  Draft of Standard FDS 
 
 
 
 
TC05 -2إعداد اللجنة الفرعية الخليجية رقم  
 
Prepared by GSO Technical Sub-Committee No. TC05 -2 
 
 
تحديث  
GSO 2481 / 201 9 
 
 
الحدود القصوى المسموح بها من بقايا الادوية البيطرية في الاغذية  
Maximum  Residues Limits (Mrls) of Veterinary Drugs In Food 
 
 
 
 
 
 
I.C.S: 67.040.00  
هذه الوثيقة مشروع لمواصفة قياسية خليجية تم 
توزيعها لإبداء الرأي والملحوظات بشأنها ، لذلك 
فإنها عرض ة للتغيير والتبديل،  ولا يجوز الرجوع 
إليها كمواصفة قياسية خليجية إلا بعد اعتمادها من 
الهيئة. This document is a draft GSO Standard 
circulated for comments. It is, therefore ,  
subject to alteration and modification and 
may not be referred to as a GSO Standard 
until approved by GSO .  
    
 
تقديم 
هيئة التقييس لدول  مجلس التعاون  لدول  الخليج العربية هيئة إقليمية تضم في عضويتها أجهزة التقييس 
الوطنية في الدول  الأعضاء ، ومن مهام الهيئة إعداد المواصفات القياسية واللوائح الفنية الخليجية 
بواسطة لجان فنية متخصصة . 
 
قرر (المجلس الفني لـ/مجلس إدارة) هيئة التقييس لدول مجلس التعاون لدول الخليج العربية في اجتماعه رقم  
() الذي عقد بتاريخ / /  هـ ،الموافق  /  /  م اعتماد تحديث (اللائحة الفنية) الخليجية  (GSO 2481 الحدود 
القصوى  المسموح بها من بقايا الادوية البيطرية في الاغذية) باللغة (العربية/الإنجليزية) التي تم دراستها  
وإعدادها ضمن برنامج عمل (اللجنة الفنية ) الخليجية رقم TC05-2"   "اللجنة الفنيـة الفرعية الخليجية 
لمواصفات المواد المضافة وملوثات الأغذية " المدرجة في خطة  (المملكة العربية السعودية ). 
على أن تلغي المواصفة القياسية/اللائحة الفنية الخليجية رقم   ) / (وَتحل  محلها. 
 
 
 
 
 1 
  الحدود القصوى المسموح بها من بقايا الادوية البيطرية في الاغذية 
 
 
1    المجال:  
تختص هذه المواصفة القياسية الخليجية بالحدود القصوى المسموح بها لمتبقيات الأدوية 
البيطرية في المنتجات الغذائية والغذاء من أصل حيواني. 
2    المراجع التكميلية 
1.2 GSO 592        " طرق أخذ عينات اللحوم ومنتجاتها " .                                                         
2.2   GSO 2475   "طرق أخذ العينات لتقدير بقايا الأدوية البيطرية في الأغذية -الجزء 
الأول: منتجات اللحوم والدواجن " .   
3.2  المواصفة القياسية الخليجية التي تعتمدها الهيئة والخاصة بـ " طرق تقدير بقايا العقاقير
البيطرية في اللحوم ومنتجات اللحوم" .                    
     3التعاريف 
1.3  الدواء البيطري : هو أي مادة توصف أو تطبق أو تعطى لأي حيوان منتج للغذاء مثل 
الحيوانات المنتج ة للحوم أو الحليب. الدواجن. الأسماك سواء كان استخدامها لأغراض 
علاجية وقائية أو تشخيصية أو كمحفزات للنمو .  
2.3  متبقيات الأدوية البيطرية : وهي المواد التي تتواجد في المنتجات الغذائية من أصل حيواني 
كنتيجة لاستخدام الأدوية البيطرية. وهذه تعتمد على المركبات الأصلية و/أو نواتج أيضه ا 
داخل الجسم وكذلك بقايا الأدوية البيطرية غير النقية. 
3.3  الحدود القصوى للمتبقيات : هو الحد الأقصى المسموح لمتبقي دواء بيطري ناتج من رعاية
حيوانية وبيطرية جيدة وموصى به من هيئة الدستور الغذاء والهيئات الدولية الأخرى وذلك 
ليكون حد قانوني مسموح به في الغذاء أو مضافاً إليه. يعبر عن هذه الحدود كتركيزات تق اس 
بالمايكرو جرام من البقايا للكيلو غرام من المادة الغذائية (مكجم/كجم) (µg/kg. ) مواصفة  قياسية خليجية  GSO  2481/2019  
  
 
 
2 
         4.3  المعدل المسموح تناوله يومي : هو الكمية المتبقية من الدواء البيطري ، التي تحسب على 
أساس وزن الجسم، والتي يمكن تناولها يوميا على مدى عمر الإنسان دون أي مخاطر صحية معتبرة 
(متوسط وزن الإنسان 60 كجم 
4-  المتطلبات : 
 يجب أن لا تتعدى بقايا الأدوية البيطرية في الأغذية ذات الأصل الحيواني حدود معينة والتي 
تم توصيف كل منها في الجداول التالية : 
5-  قائمةالأدوية البيطرية :  
Veterinary Drugs List:  
Abamectin  ................................ ................................ ................................ ................................ .....................  4 
Albendazole  ................................ ................................ ................................ ................................ ..................  4 
Amoxici llin ................................ ................................ ................................ ................................ ...................  4 
Ampicillin  ................................ ................................ ................................ ................................ .....................  5 
Avilamycin  ................................ ................................ ................................ ................................ ...................  6 
Benzyl  ................................ ................................ ................................ ................................ ............................  7 
Ceftiofur  ................................ ................................ ................................ ................................ ........................  7 
Chlortetracycline/Oxytetracycline/Tetracycline  ................................ ................................ ...................  8 
Clenbuterol  ................................ ................................ ................................ ................................ ...................  8 
Closantel  ................................ ................................ ................................ ................................ ........................  9 
Colistin  ................................ ................................ ................................ ................................ ..........................  9 
Cyfluthrin  ................................ ................................ ................................ ................................ ....................  11 
Cyhalothrin  ................................ ................................ ................................ ................................ .................  11 
Cypermethrin And Alpha -Cypermethrin  ................................ ................................ ..............................  11 
Danofloxacin  ................................ ................................ ................................ ................................ ..............  12 
Deltamethrin  ................................ ................................ ................................ ................................ ...............  12 
Derquantel  ................................ ................................ ................................ ................................ ...................  13 
Dexamethasone  ................................ ................................ ................................ ................................ ..........  13 
Diclazuril  ................................ ................................ ................................ ................................ .....................  14 
DICYCLANIL  ................................ ................................ ................................ ................................ ...........  14 
Dihydrostreptomycin/ streptomycin  ................................ ................................ ................................ ...... 15 
Diminazene  ................................ ................................ ................................ ................................ .................  16 
Doramectin  ................................ ................................ ................................ ................................ .................  16 
Emamectin Benzoate  ................................ ................................ ................................ ................................  17 
Eprinomectin  ................................ ................................ ................................ ................................ ..............  17 
ERYTHROMYCIN  ................................ ................................ ................................ ................................ .. 18 
ESTRADIOL -17BETA  ................................ ................................ ................................ ............................  18 
FEBANTEL/FENBENDAZOLE/OXFENDAZOLE  ................................ ................................ ........  18 
FLUAZURON  ................................ ................................ ................................ ................................ ...........  19 
FLUBENDAZOLE  ................................ ................................ ................................ ................................ ... 20 
FLUMEQUINE  ................................ ................................ ................................ ................................ .........  20 
GENTAMICIN  ................................ ................................ ................................ ................................ ..........  21 مواصفة  قياسية خليجية  GSO  2481/2019  
  
 
 
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 IMIDOCARB  ................................ ................................ ................................ ................................ .............  21 
ISOMETAMIDIUM  ................................ ................................ ................................ ................................ . 21 
IVERMECTIN  ................................ ................................ ................................ ................................ ...........  22 
LASALOCID SODIUM  ................................ ................................ ................................ ..........................  23 
LEVAMISOLE  ................................ ................................ ................................ ................................ ..........  24 
LINCOMYCIN  ................................ ................................ ................................ ................................ ..........  24 
LUFENURON  ................................ ................................ ................................ ................................ ...........  25 
MELENGESTROL ACETATE  ................................ ................................ ................................ .............  25 
MONENSIN  ................................ ................................ ................................ ................................ ...............  25 
MONEPANTEL  ................................ ................................ ................................ ................................ ........  27 
MOXIDECTIN  ................................ ................................ ................................ ................................ ..........  27 
NARASIN  ................................ ................................ ................................ ................................ ...................  28 
NEOMYCIN  ................................ ................................ ................................ ................................ ..............  28 
NICARBAZIN  ................................ ................................ ................................ ................................ ...........  30 
PHOXIM  ................................ ................................ ................................ ................................ .....................  30 
Pirlimycin  ................................ ................................ ................................ ................................ ....................  30 
PROGESTERONE  ................................ ................................ ................................ ................................ ... 31 
RACTOPAMINE  ................................ ................................ ................................ ................................ ...... 31 
SARAFLOXACIN  ................................ ................................ ................................ ................................ .... 32 
SPECTINOMYCIN  ................................ ................................ ................................ ................................ .. 32 
SPIRAMYCIN  ................................ ................................ ................................ ................................ ...........  33 
SULFADIMIDINE  ................................ ................................ ................................ ................................ ... 33 
TEFLUBENZURON  ................................ ................................ ................................ ................................  34 
TESTOSTERONE  ................................ ................................ ................................ ................................ .... 34 
THIABENDAZOLE  ................................ ................................ ................................ ................................ . 34 
TILMICOSIN ................................ ................................ ................................ ................................ .............  35 
TRENBOLONE ................................ ................................ ................................ ................................ .........  36 
TRICHLORFON  ................................ ................................ ................................ ................................ ....... 36 
TRICLABENDAZOLE  ................................ ................................ ................................ ...........................  36 
TYLOSIN  ................................ ................................ ................................ ................................ ...................  36 
ZERANOL  ................................ ................................ ................................ ................................ ..................  37 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 مواصفة  قياسية خليجية  GSO  2481/2019  
  
 
 
4 
 6- الحدود القصوى المسموح بها من بقايا الأدوية البيطرية في الأغذية : 
Abamectin  (Anthelmintic agent    (مضاد الديدان   
Acceptable Daily Intake (ADI)   0-2 µg/kg body weight  
Residue Definition  Avermectin B1a 
Species Tissue MRL (μg/kg) Referance Notes 
Cattle  Liver  100 
CAC 26 (2003)  
  
Kidney  50  
Fat 100  
 
Albendazole  (Anthelmintic agent    (مضاد الديدان   
Acceptable Daily Intake (ADI)   0-50 µg/kg body weight  
Residue  Definition  Exp milk, 2 -aminosulfone metabolite: milk not yet 
identified   
Species Tissue MRL (μg/kg) Referance Notes 
Not specified  Muscle  100 
CAC 20 (1993)  
  
Liver  5000   
Kidney  5000   
Fat 100  
Milk 
(μg/l)  100  
 
Amoxicillin  (Antimicrobial agent    (مضاد الميكروبات   
Microbiologicale 
Acceptable Daily Intake 
(ADI)   0-0.002 mg/kg body weight based on the effects of Amoxicillin 
on the intestinal microbiota  
Acute Reference Dose  0.005  mg/kg bw based on microbiological effects on the 
intestinal microbiota  
Estimated Chronic 
Dietary Exposure  0.14 μg/kg bw per day (for the general population), which 
represents 7% of the upper bound of the mADI  
Estimated Acute Dietary 
Exposure  1.4 μg/kg bw ( for the general population), which represents 
28% of the microbiological ARfD  مواصفة  قياسية خليجية  GSO  2481/2019  
  
 
 
5 
 1.6 μg/kg bw (for children), which represents 31% of the 
microbiological ARfD  
Residue Definition  Amoxicillin 
Species Tissue MRL (μg/kg) Referance Notes 
Cattle  Muscle  50 
CAC 3 5 (2012)  
  
Liver  50  
Kidney  50  
Fat 50  
Milk  4  
Sheep  Muscle  50  
Liver  50  
Kidney  50  
Fat 50  
Milk  4  
Finish  Fillet  50 CAC 41 (2018)  
 The term “finfish”includes all 
fish species.  
Muscle plus skin in natural 
proportion   
Muscle  50 The term “finfish”includes all 
fish species.  
 
Ampicillin  (Antimicrobial agent    (مضاد الميكروبات   
Acceptable Daily Intake 
(ADI)   100 ug/kg body weight  
 
Acute Reference Dose  0.012 mg/kg bw based on the microbiological end -point.  
Estimated Chronic 
Dietary Exposure  0.29 μg/kg bw per day (for the general population), which 
represents 10% of the upper bound of the ADI.  
Estimated Acute Dietary 
Exposure  1.9 μg/kg bw per day (for the general population), which 
represents 16% of the ARfD.  
1.7 μg/kg bw per day (for children), which represents 14% of 
the ARfD.  
Residue Definition  Ampicillin مواصفة  قياسية خليجية  GSO  2481/2019  
  
 
 
6 
 Species Tissue MRL (μg/kg) Referance Notes 
Finish  Fillet  50 CAC 41 (2018)  
 The term “finfish”includes all 
fish species.  
Muscle plus skin in natural 
proportion   
Muscle  50 The term “finfish”includes all 
fish species.  
 
Avilamycin  (Antimicrobial Drugs    (مضادالميكروبات   
Acceptable Daily Intake (ADI)   0-2 mg/kg body weight  on the basis of a NOAEL of 150 
mg avilamycin activity/kg bw per day and a safety factor 
of 100 and rounding to one significant figure (JECFA70)  
Residue Definition  Dichloroisoevernin ic acid (DIA)  
Species Tissue MRL (μg/kg) Referance Notes 
Chicken  Muscle  200 
CAC 32 (2009)  
  
Liver  300  
Kidney  200  
Fat/Skin  200  
Turkey  Muscle  200 
CAC 32 (2009)  
  
Liver  300  
Kidney  200  
Fat/S kin 200  
Rabbits  Muscle  200 
CAC 32 (2009)  
  
Liver  300  
Kidney  200  
Fat/skin  200  
 
 مواصفة  قياسية خليجية  GSO  2481/2019  
  
 
 
7 
 Benzyl  penicillin  (Antimicrobial Agent    (مضادالميكروبات   
Acceptable Daily Intake (ADI)   30 μg penicillin/person/day  
Residue Definition  Benzylpenicillin 
Species Tissue MRL (μg/kg) Referance Notes 
Catle  Muscle  50 
CAC 23 (1999)  
  
Liver  50  
Kidney  50  
Milk μg/l  4  
Chicken   
Muscle  50 
CAC 23 (1999)  
 Applies to procaine 
benzylpenicillin 
only.   
Liver  50 
 
Kidney  50 
 
 
Ceftiofur  (Antimicrobial Agent    (مضادالميكروبات  
Acceptable Daily Inta ke 
(ADI)   0 - 50 μg/kg body weight  
Residue Definition  Desfuroylceftiofur 
Species Tissue MRL (μg/kg) Referance Notes 
Cattle  Muscle  1000  
CAC 23 (1999)  
  
Liver  2000   
Kidney  6000   
 Fat 2000   
Milk 
(µg/l)  100  
 
 مواصفة  قياسية خليجية  GSO  2481/2019  
  
 
 
8 
 Chlortetracycline/Oxytetracycline/ Tetracycline  (Antimicrobial Drugs    
(مضادالميكروبات  
Acceptable Daily Intake (ADI)   0-30 µg/kg body weight  
Residue Definition  Parent drugs, singly or in combination 
Species Tissue MRL (μg/kg) Referance Notes 
Cattle  Muscle  200 
CAC 26 
(2003)  
  
Liver  600  
Kidney  1200   
Milk 
(µg/l)  100  
Sheep  Muscle  200 
CAC 26 
(2003)  
  
Liver  600  
Kidney  1200   
Milk 
(µg/l)  100  
Poultry  Muscle  200 
CAC 26 
(2003)  
  
Liver  600  
Kidney  1200   
Eggs  400  
Fish 
Muscle  200 CAC 26 
(2003)  
 Applies only to 
oxytetracycline  
Giant prawn 
(Paeneus monodon)  Muscle  200 CAC 26 
(2003)  
 Applies only to 
oxytetracycline  
 
 
Clenbuterol  (adrenoceptor agonist    (مضاد البكتريا  
Acceptable Daily Intake (ADI)  0-0.004 µg/kg body weight  
Residue Definition  Clenbuterol 
Species Tissue MRL (μg/kg) Referance Notes 
Cattle  Muscle  0.2 
CAC 26 
(2003)  
 Due to the potential 
abuse of this drug, the 
MRLs are 
recommended only 
when  associated with 
a nationally approved 
therapeutic use, such  
Liver  0.6 
 
Kidney  0.6 
 
Fat 0.2 مواصفة  قياسية خليجية  GSO  2481/2019  
  
 
 
9 
 Milk 
(µg/l)  0.05 as tocolysis or as an 
adjunt therapy in 
respiratory diseases  
Horse  Muscle  
 0.2 
CAC 26 
(2003)  
 Due to the potential 
abuse of this drug, the 
MRLs are 
recommended only 
when associated with 
a nationally approved 
therapeutic use, such 
as tocolysis or as an 
adjunt therapy in 
respiratory diseases  Liver  
 0.6 
Kidney  
 0.6 
Fat 0.2 
 
 
Closantel  (Anthelmintic agents   (مضاد الديدان  
Acceptable Daily Intake 
(ADI)  0-30 μg/kg body weight  
Species Tissue MRL (μg/kg) Referance Notes 
Cattle  Muscle  1000  
 
CAC 20 (1993)  
  
Liver  1000   
Kidney  3000   
Fat 3000   
Sheep  Muscle  1500  
CAC 20 (1993)  
  
Liver  1500   
Kidney  5000   
Sheep  Fat 2000  CAC 20 (1993)  
  
 
 
Colistin  (Antimicrobial Drugs    (مضادالميكروبات  
Acceptable Daily Intake (ADI)  0-7 µg/kg body weight  
Residue Definition  Sum of colistin A and colistin B 
Species Tissue MRL (μg/kg) Referance Notes 
Cattle  Muscle  150 CAC 31 
(2008)   
Liver  150  مواصفة  قياسية خليجية  GSO  2481/2019  
  
 
 
10 
 Kidney  200  
Fat 150  
Milk 
(µg/l)  50  
Sheep  Muscle  150 
CAC 31 
(2008)   
Liver  150  
Kidney  200  
Fat 150  
Milk 
(µg/l)  50  
Goat  Muscle  150 
CAC 31 
(2008)   
Liver  150  
Kidney  200  
Fat 150  
Chicken  Muscle  150 
CAC 31 
(2008)   
Liver  150  
Kidney  200  
Fat 150 The MRL includes 
skin + fat  
Eggs  300  
Tukey  Muscle  150 
CAC 31 
(2008)   
Liver  150  
Kidney  200  
Fat 150 The MRL includes 
skin + fat  
Rabbit  Muscle  150 CAC 31 
(2008)   
 Liver  150   
Kidne y 200  
Fat 150  
 
 مواصفة  قياسية خليجية  GSO  2481/2019  
  
 
 
11 
 Cyfluthrin  (insecticide    (مبيد حشري  
Acceptable Daily Intake (ADI)  0-20 µg/kg body weight  
Residue Definition  Cyfluthrin 
Species  Tissue  MRL (μg/kg)  Referance  Notes  
Cattle  Muscle  20 
CAC 26 
(2003)  
Liver  20  
Kidney  20  
Fat 200  
Milk 
(µg/l)  40  
 
Cyhalothrin  (insecticide    (مبيد حشري  
Acceptable Daily Intake (ADI)  0-5 µg/kg body weight  
Residue Definition  Cyhalothrin  
Species  Tissue  MRL (μg/kg)  Referance  Notes  
Cattle  Muscle  20 
CAC 28 
(2005)   
Liver  20  
Kidney  20  
Fat 400  
Milk 
(µg/l)  30  
Sheep  Muscle  20 
CAC 28 
(2005)   
Liver  50  
Kidney  20  
Fat 400  
 
 
 
Cypermethrin And Alpha -Cypermethrin  (insecticide    (مبيد حشري  
Acceptable Daily Intake (ADI)  0-20 µg/kg body weight for both Cypermethrin And 
Alpha -Cyper methrin  
Residue Definition  Total of cypermethrin residues resulting from the use of 
cypermethrin or alpha -cypermethrin as veterinary drugs  
Species Tissue MRL (μg/kg) Referance Notes مواصفة  قياسية خليجية  GSO  2481/2019  
  
 
 
12 
 Cattle  Muscle  50 
CAC 29 
(2008)   
Liver  50  
Kidney  50  
Fat 1000  
Milk 
(µg/l)  100  
Sheep  Muscle  50 
CAC 29 
(2008)   
Liver  50  
Kidney  50  
Fat 1000   
 
Danofloxacin  (Antimicrobial Drugs    (مضادالميكروبات  
Acceptable Daily Intake (ADI)  0-20 µg/kg body weight  
Residue Definition  Danofloxacin 
Species Tissue MRL ( μg/kg)  Referance Notes 
Cattle  Muscle  200 
CAC 24 
(2001)   
Liver  400  
Kidney  400  
Fat 100  
Shicken  Muscle  200 
CAC 24 
(2001)   
Liver  400  
Kidney  400  
Fat 100 Fat/skin in normal 
proportion  
 
 
Deltamethrin  (insecticide    (مبيد حشري  
Acceptable  Daily Intake (ADI)  0-10 µg/kg body weight  
Residue Definition  Deltamethrin  
Species Tissue MRL (μg/kg) Referance Notes 
Cattle  Muscle  30 
CAC 26 
(2003)   
Liver  50  مواصفة  قياسية خليجية  GSO  2481/2019  
  
 
 
13 
 Kidney  50  
Fat 500  
Milk 
(µg/l)  30  
Chicken  Muscle  30 
CAC 26 
(2003)   
Liver  50  
Kidney  50  
Fat 500  
Eggs  30  
Salmon  Muscle  30 CAC 26 
(2003)   
Sheep  Muscle  30 
CAC 26 
(2003)   
Liver  50  
Kidney  50  
Fat 500  
 
Derquantel  (Anthelmintic agents   (مضاد الديدان  
Acceptable Daily Intake (ADI)  0-0.3 µg/kg body weight  
Residu e Definition  Derquantel  
Species Tissue MRL (μg/kg) Referance Notes 
Sheep  Muscle  0.3 
CAC 38 
(2015)   
Liver  0.8  
Kidney  0.4  
Fat 7.0  
 
 
Dexamethasone  (glucocorticosteroid   (مضادات الالتهابات الستيرودية  
Acceptable Daily Intake (ADI)  0-0.015 µg/kg  body weight  
Residue Definition  Dexamethasone  
Species Tissue MRL (μg/kg) Referance Notes 
Cattle  Muscle  1.0 
 CAC 32 
(2009)   
Liver  2.0  مواصفة  قياسية خليجية  GSO  2481/2019  
  
 
 
14 
 Kidney  1.0  
Milk 
(µg/l)  0.3  
Horses  Muscle  1.0 
CAC 32 
(2009)   
Liver  2.0  
Kidney  1.0  
 
 
Diclazuril  (antiprotozoal agent   (مضادات الطفيليات  
Acceptable Daily Intake (ADI)  0-0.30 µg/kg body weight  
Residue Definition  Diclazuril  
Species Tissue MRL (μg/kg) Referance Notes 
poultry  Muscle  500 
 
CAC 23 
(1999)   
Liver  3000   
Kidney  2000   
Fat/S kin 1000   
Rabbit Muscle  500 
CAC 23 
(1999)   
Liver  3000   
Kidney  2000   
Fat 1000   
Sheep  Muscle  500 
CAC 23 
(1999)   
Liver  3000   
Kidney  2000   
Fat 1000   
 
DICYCLANIL (Insecticide  (مبيد حشري  
Acceptable Daily Intake (ADI)  0-7 µg/kg body weight  
Residue Defin ition Dicyclanil  
Species Tissue MRL (μg/kg) Referance Notes 
Sheep  Muscle  150 
CAC 28 
(2005)   
Liver  125  مواصفة  قياسية خليجية  GSO  2481/2019  
  
 
 
15 
 Kidney  125  
Fat 200  
 
 
Dihydrostreptomycin/ streptomycin  (Antimicrobial Drugs (مضاد الميكروبات  
Acceptable Daily Intake (ADI)  0-50 µg/kg body  weight  
Residue Definition  Sum of dihydrostreptomycin and streptomycin  
Species Tissue MRL (μg/kg) Referance Notes 
Cattle  Muscle  600 
CAC 24 
(2001)   
Liver  600  
Kidney  1000   
Fat 600  
Milk 
(µg/l)  200 CAC 26 
(2003)   
Chicken  Muscle  600 
CAC 24 
(2001)  
Liver  600  
Kidney  1000   
Fat 600  
Sheep  Muscle  
 600 
CAC 24 
(2001)   
Liver  600  
Kidney  1000   
Fat 600  
Milk 
(µg/l)  200 
CAC 26 
(2003)   
 
 
 
 
 
 
 مواصفة  قياسية خليجية  GSO  2481/2019  
  
 
 
16 
 Diminazene  (trypanocide (مضادات الطفيليات  
Acceptable Daily Intake (ADI)  0-100 µg/kg body wei ght 
Residue Definition  Diminazene  
Species Tissue MRL (μg/kg) Referance Notes 
Cattle  Muscle  500 
CAC 22 
(1997)   
Liver  12000   
Kidney  60000   
Milk 
(µg/l)  150 LOQ of the analytical 
method  
 
 
Doramectin  (Anthelmintic agents (مضادات الديدان  
Acceptable  Daily Intake (ADI)  0-1 µg/kg body weight  
Residue Definition  Doramectin  
Species Tissue MRL (μg/kg) Referance Notes 
Cattle  Muscle  10 
CAC 22 
(1997)  High concentration of 
residues at the 
injection site over a 35 
day period after 
subcutaneous or 
intramuscul ar 
administration of the 
drug at the 
recommended dose 
Liver  100  
Kidney  30  
Fat 150 High concentration of 
residues at the 
injection site over a 35 
day period after 
subcutaneous or 
intramuscular 
administration of the 
drug at the 
recommended dose 
Milk 
(µg/l)  15 
CAC 29 
(2006)  Depending on the 
route and/or time of 
administration the use 
of doramectin in dairy 
cows may result in 
extended withdrawal مواصفة  قياسية خليجية  GSO  2481/2019  
  
 
 
17 
 periods in milk. This 
may be addressed in 
national/regional 
regulatory 
programmes.  
 
 
Emamectin Benzoate  (antiparasitic agent   (مضادالطفيليات  
Acceptable Daily Intake 
(ADI)  ADI of 0 –0.5 μg/kg bw established by JMPR (2011), based on 
an overall NOAEL of 0.25 mg/kg bw per day for neurotoxicity 
from 14 - and 53 -week studies in dogs, supported by an overall 
NOAE L of 0.25 mg/kg bw per day from 1 - and 2 -year studies in 
rats. An uncertainty factor of 500 was applied to the NOAEL, 
which includes an additional uncertainty factor of 5 to account 
for the steep dose –response curve and irreversible 
histopathological effec ts in neural tissues at the lowest -
observed -adverse -effect level (LOAEL) in dogs, as used by 
JMPR and confirmed by JECFA78.  
 
Estimated  Dietary 
Exposure  11 μg/person per day, which represents approximately 37% of 
the upper bound of the ADI (JECFA78)  
Residue Definition  Emamectin B1a 
Species Tissue MRL (μg/kg) Referance Notes 
Salmon  Muscle  100 
CAC 38 (2015) 
  
Fillet  100 Muscle plus skin in natural 
proportion  
Trout  Muscle  100 CAC 38 (2015)   
Fillet  100 Muscle plus skin in natural 
proportion  
 
Eprinom ectin  (anthelmintic agent (مضادات الديدان  
Acceptable Daily Intake (ADI)  0-10 µg/kg body weight  
Residue Definition  Eprinomectin B1a  
Species Tissue MRL (μg/kg) Referance Notes 
Cattle  
 Muscle  100 
CAC 26 
(2003)   
Liver  2000   
Kidney  300  
Fat 250  
Milk 
(µg/l)  20  
 مواصفة  قياسية خليجية  GSO  2481/2019  
  
 
 
18 
  
ERYTHROMYCIN  (Antimicrobial agent (مضادالميكروبات  
Acceptable Daily Intake (ADI)  0-0.7 µg/kg body weight  
Residue Definition  Erythromycin A  
Species Tissue MRL (μg/kg) Referance Notes 
Chicken  Muscle  100 
CAC 31 
(2008)   
Liver  100  
Kidney  100  
Fat 100 The MRL includes 
skin + fat  
Eggs  50  
Turkey  Muscle  100 
CAC 31 
(2008)   
Liver  100  
Kidney  100  
Fat 100 The MRL includes 
skin + fat  
 
ESTRADIOL -17BETA  (production aid (مساعد انتاج  
Acceptable Daily Intake (ADI)  unnecessary  (JECFA32); 0 -0.05 μg/kg weight  
(JECFA52)  
Residue Definition  Estradiol -17beta.  
Species Tissue MRL (μg/kg) Referance Notes 
Cattle  Muscle  unnecessary  
CAC 21 
(1995 ) Residues resulting from the 
use of this substance as a 
growth promoter in 
accordance with g ood 
animal husbandry practice 
are unlikely to pose a 
hazard to human health  
 Liver  unnecessary  
Kidney  unnecessary  
Fat unnecessary  
 
 
FEBANTEL/FENBENDAZOLE/OXFENDAZOLE  (anthelmintic agent (مضادالديدان  
Acceptable Daily Intake (ADI)  Group ADI o f 0-7 μg/kg body weight  
Residue Definition  Sum of fenbendazole, oxfendazole and oxfendazole 
sulphone, expressed as oxfendazole sulphone 
equivalents  
Species Tissue MRL (μg/kg) Referance Notes مواصفة  قياسية خليجية  GSO  2481/2019  
  
 
 
19 
 Cattle  Muscle  100 
CAC 23 
(1999)   
Liver  500  
Kidney  100  
Fat 100  
Milk 
(µg/l)  100  
Goat  Muscle  100 
CAC 23 
(1999)   
Liver  500  
Kidney  100  
Fat 100  
Horse  Muscle  
 100 
CAC 23 
(1999)   
Liver  500  
 Kidney  100   
Fat 100   
Sheep  Muscle  100 
CAC 23 
(1999)   
Liver  500  
Kidney  100  
Fat 100  
Milk 
(µg/l)  100  
 
 
FLUAZURON  (insecticide    (مبيد حشري  
Acceptable Daily Intake (ADI)  0-40 µg/kg body weight  
Residue Definition  Fluazuron  
Species Tissue MRL (μg/kg) Referance Notes 
Cattle  Muscle  200 
CAC 23 
(1999)   
Liver  500  
Kidney  500  
Fat 7000   مواصفة  قياسية خليجية  GSO  2481/2019  
  
 
 
20 
  
FLUBENDAZOLE  (anthelmintic agent (مضادالديدان  
Acceptable Daily Intake (ADI)  0-12 µg/kg body weight  
Residue Definition  Flubendazole  
Species Tissue MRL (μg/kg) Referance Notes 
Poultry  Muscle  200 
CAC 21 
(1995)   
Liver  500  
Eggs  400  
 
FLUMEQUINE  (Antimicrobial agent (مضادالميكروبات  
Acce ptable Daily Intake (ADI)  0-30  µg/kg body weight  
Residue Definition  Flumequine  
Species Tissue MRL (μg/kg) Referance Notes 
Cattle  Muscle  500 
CAC 28 
(2005)   
Liver  500  
Kidney  3000   
Fat 1000   
Chicken  Muscle  500 
CAC 28 
(2005)   
Liver  500  
Kidney 3000   
Fat 1000   
Sheep  Muscle  500 
CAC 28 
(2005)   
Liver  500  
Kidney  3000   
Fat 1000   
Trout  Muscle  500 CAC 28 
(2005)  Muscle including 
normal proportion of 
skin 
 مواصفة  قياسية خليجية  GSO  2481/2019  
  
 
 
21 
  
 
GENTAMICIN  (Antimicrobial agent (مضادالميكروبات  
Acceptable Daily Intake (A DI) 0-20  µg/kg body weight  
Residue Definition  Gentamicin  
Species Tissue MRL (μg/kg) Referance Notes 
Cattle  Muscle  100 
CAC 24 
(2001)   
Liver  2000   
Kidney  5000   
Fat 100  
Milk 
(µg/l)  200  
 
 
IMIDOCARB  (antiprotozoal agent (مضادالطفيليات  
Accep table Daily Intake (ADI)  0-10  µg/kg body weight  
Residue Definition  Flumequine  
Species Tissue MRL (μg/kg) Referance Notes 
Cattle  Muscle  300 
CAC 28 
(2005)   
Liver  1500   
Kidney  2000   
Fat 50  
Milk (μg/l)  50  
 
ISOMETAMIDIUM  (Trypanocide (مضادالطفيليات  
Acceptable Daily Intake (ADI)  0-100  µg/kg body weight  
Residue Definition  Flumequine  
Species Tissue MRL (μg/kg) Referance Notes 
Cattle  Muscle  
100 
CAC 21 
(1995)   
Liver  
500  
Kidney  
1000   
Fat 
100  
Milk (μg/l)  
100  مواصفة  قياسية خليجية  GSO  2481/2019  
  
 
 
22 
  
IVERMECTIN  (anthelm intic agent (مضادالديدان  
Acceptable Daily Intake 
(ADI)  0-10 μg/kg bw on the basis of a NOAEL of 0.5 mg/kg bw per 
day for neurological effects (mydriasis) and retardation of 
weight gain in a 14 -week dog study, with application of an 
uncertainty factor of 50 (5 for interspecies differences based on 
pharmacokinetic studies in dogs and humans and 10 for 
intraspecies differences). The previous ADI of 0 -1 μg/kg bw 
was withdrawn. (JECFA81)  
Estimated Chronic 
Dietary Exposure  The estimated daily intake (EDI) is 3 8 μg/person per day, based 
on a 60 kg individual, which represents 6% of the upper bound 
of the ADI. The GECDE for the general population is 0.9 μg/kg 
bw per day, which represents 9% of the upper bound of the 
ADI. The GECDE for children is 1.5 μg/kg body w eight per 
day, which represents 15% of the upper bound of the ADI. The 
GECDE for infants is 1.3 μg/kg bw per day, which represents 
13% of the upper bound of the ADI. (JECFA81)  
Acute Reference Dose  0.2 mg/kg bw, based on a NOAEL of 1.5 mg/kg bw, the highes t 
dose tested in a safety, tolerability and pharmacokinetics study 
in healthy human subjects, with application of an uncertainty 
factor of 10 for intraspecies variability. (JECFA81)  
Estimated Acute Dietary 
Exposure  A combined analysis of all studies submi tted showed that after 
14 days, the maximum values of residues found at injection 
sites led to a GEADE of 52 μg/kg bw for the general population 
and 87 μg/kg bw for children, corresponding, respectively, to 
27% and 43% of the ARfD. (JECFA81)  
Residue Defin ition Ivermectin B1a 
Species Tissue MRL (μg/kg) Referance Notes 
Cattle  Muscle  30 
CAC 40 (2017)  
  
Liver  800  
Kidney  100  
Fat 400  
Milk  10  
Sheep  Liver  15 
CAC 20 (1993)  
  
Fat 20  
 
 
 
 مواصفة  قياسية خليجية  GSO  2481/2019  
  
 
 
23 
 LASALOCID SODIUM  (anthelmintic agent (مضادالديدان  
Acce ptable Daily Intake 
(ADI)  0-5 μg/kg bw on the basis of a NOAEL of 0.5 mg/kg bw per 
day from a developmental toxicity study in rabbits and a 
multigeneration reproductive toxicity study in rats, with 
application of an uncertainty factor of 100 for interspeci es and 
intraspecies variability. (JECFA78)  
Estimated Dietary 
Exposure  80 μg/person per day was calculated, which represents 
approximately 27% of the upper bound of the ADI (JECFA78)  
Residue Definition  Lasalocid A 
Note  JECFA78 extended the MRLs in chicke n to turkey and quail 
and extrapolated the MRLs in chicken to pheasant. No 
information was available for duck, including on approved uses. 
As the compound is not registered for use in laying hens, 
according to the sponsor, it is not appropriate to recommen d 
MRLs for egg. 
Species Tissue MRL (μg/kg) Referance Notes 
Chicken  Muscle  400 
CAC 40 (2017)  
  
Liver  1200   
Kidney  600  
Skin + 
fat 600  
Turkey  Muscle  400 
CAC 40 (2017)  
  
Liver  1200   
Kidney  600 
  
Skin + 
fat 600  
Quail  Muscle  400 
CAC 40 (2 017) 
  
Liver  1200   
Kidney  600  
Skin + 
fat 600  
Pheasant  Muscle  400 
CAC 40 (2017)  
  
Liver  1200   
Kidney  600  
Skin + 
fat 600  
 مواصفة  قياسية خليجية  GSO  2481/2019  
  
 
 
24 
 LEVAMISOLE  (anthelmintic agent (مضادالديدان  
Acceptable Daily Intake 
(ADI)  0-6 μg/kg body weight  
Residue Defin ition Levamisole 
Species Tissue MRL (μg/kg) Referance Notes 
Cattle  Muscle  10 
CAC 22 (1997 ) 
  
Liver  100  
Kidney  10  
Skin 10  
Poultry  Muscle  10 
CAC 22 (1997)  
  
Liver  100  
Kidney  10  
Fat 10  
Sheep  Muscle  10 
CAC 22 (1997)  
  
Liver  100  
Kidney  10  
Fat 10  
 
LINCOMYCIN  (antimicrobial agent (مضادالميكروبات  
Acceptable Daily Intake 
(ADI)  0-30 μg/kg body weight  
Residue Definition  Lincomycin 
Species Tissue MRL (μg/kg) Referance Notes 
Cattle  Milk  150 CAC 26 (2003)  
  
Chicken  Muscle  200 
CAC 2 6 (2003 ) 
  
Liver  500  
Kidney  500  
Fat 100 Additional MRL for skin 
with adhering fat of 300 
μg/kg  
 
 مواصفة  قياسية خليجية  GSO  2481/2019  
  
 
 
25 
 LUFENURON  (insecticide (مبيد حشري  
Acceptable Daily Intake 
(ADI)  0–0.02 mg/kg bw based on the NOAEL of 1.93 mg/kg bw per 
day for tonic -cloni c seizures and findings in lungs, 
gastrointestinal tract, liver and urinary tract in a 2 -year dietary 
study in rats, and using a safety factor of 100 (10 for 
interspecies variability and 10 for intraspecies variability)  
Acute Reference Dose  Unnecessary, i n view of lufenuron low acute oral toxicity and 
the absence of developmental toxicity and other toxicological 
effects likely to be elicited by a single dose.  
Estimated Chronic 
Dietary Exposure  1.1 μg/kg bw per day (for the general population), which 
repre sents 5.5% of the upper bound of the ADI. As lufenuron is 
also used as pesticide, the overall dietary exposure was 
estimated. The assumptions and detailed results will be 
displayed in the JECFA85 report. Results below are only for 
use as veterinary drug.  
Residue Definition  Lufenuron 
Species Tissue MRL (μg/kg) Referance Notes 
Salmon Fillet 1350 CAC 41 (2018)  
 Muscle plus skin in natural 
proportion 
Trout Fillet 1350 CAC 41 (2018)  
 Muscle plus skin in natural 
proportion 
 
 
MELENGESTROL ACETATE  (production aid (مساعد النمو  
Acceptable Daily Intake 
(ADI)  0-0.03 μg/kg body weight  
Residue Definition  Melengestrol acetate 
Species Tissue MRL (μg/kg) Referance Notes 
Cattle  Muscle  1 
CAC 32 (2009)  
  
Liver  10  
Kidney  2  
Fat 18  
 
MONENSIN  (antimicrobial ag ent (مضادالميكروبات  
Acceptable Daily Intake 
(ADI)  0–10 μg/kg bw on the basis of a NOAEL of 1.14 mg/kg bw per 
day and a safety factor of 100 and rounding to one significant 
figure.  
Estimated Dietary 
Exposure  Using the revised MRL, the TMDI from JECFA70 w as 
recalculated, resulting in a value of 481 μg/person, which 
represents 80% of the upper bound of the ADI  
Residue Definition  Monensin 
Species Tissue MRL (μg/kg) Referance Notes مواصفة  قياسية خليجية  GSO  2481/2019  
  
 
 
26 
 Cattle  Muscle  10 CAC 32 (2009)  
  
Liver  100 CAC 35 (2012)  
  
Kidney  10 
CAC 32 (2009)  
  
Fat 100  
Milk  2  
Sheep  Muscle  10 
CAC 32 (2009)  
  
Liver  20  
Kidney  10  
Fat 100  
Goats  Muscle  10 
CAC 32 (2009)  
  
Liver  20  
Kidney  10  
Fat 100  
Chicken  Muscle  10 
CAC 32 (2009)  
  
Liver  10  
Kidney  10  
Fat 100  
Turkey  Muscle  10 
CAC 32 (2009)  
  
Liver  10  
Kidney  10  
Fat 100  
Quail  Muscle  10 
CAC 32 (2009)  
  
Liver  10  
Kidney  10  
Fat 100  
 
 مواصفة  قياسية خليجية  GSO  2481/2019  
  
 
 
27 
 MONEPANTEL  (Anthelmintic agents (مضاد الديدان  
Acceptable Daily Intake 
(ADI)  0–0.02 mg/kg bw based on the NOA EL of 1.93 mg/kg bw per 
day for tonic -clonic seizures and findings in lungs, 
gastrointestinal tract, liver and urinary tract in a 2 -year dietary 
study in rats, and using a safety factor of 100 (10 for 
interspecies variability and 10 for intraspecies variab ility)  
Acute Reference Dose  Unnecessary  
Estimated Dietary 
Exposure  13.7 μg per kg bw per day (for the general population), which 
represents 68% of the upper bound of the ADI  
5.0 μg per kg bw per day (for children), which represents 22% 
of the upper bound  of the ADI  
4.4 μg per kg bw per day (for infants), which represents 25% of 
the upper bound of the ADI  
Residue Definition  Monepantel sulfone, expressed as monepantel 
Species Tissue MRL (μg/kg) Referance Notes 
Sheep  Muscle  500 
CAC 38 (2015)  
  
Liver  7000  
Kidney  1700   
Fat 13000   
Cattle  Muscle  300 
CAC 41 (2018)  
  
Liver  2000   
Kidney  1000   
 Fat 7000    
 
MOXIDECTIN  (Anthelmintic agents (مضاد الديدان  
Acceptable Daily Intake 
(ADI)  0-2 μg/kg body weight  
Residue Definition  Moxidectin 
Species Tissue MRL (μg/kg) Referance Notes 
Cattle  Muscle  20 
CAC 22 (1997)  
 Very high concentration 
and great variation in the 
level of residues at the 
injection site in cattle over 
a 49 day period after 
dosing 
Liver  100  
Kidney  50  
Fat 500  مواصفة  قياسية خليجية  GSO  2481/2019  
  
 
 
28 
 Deer  
 Muscle  20 
CAC 23 (1999)  
  
Liver  100  
Kidney  50  
Fat 500  
Sheep  Muscle  50 
CAC 22 (1997)  
  
Liver  100  
Kidney  50  
Fat 500  
 
 
NARASIN  (antimicrobial agent (مضادالميكروبات  
Acceptable Daily Intake 
(ADI)  0-5 μg/kg bw on the basis of a NOAEL of 0.5 m g/kg bw per 
day and a safety factor of 100.  
Residue Definition  Narasin A 
Species Tissue MRL (μg/kg) Referance Notes 
Cattle  Muscle  15 
CAC 35 (2012)  
  
Liver  50  
Kidney  15  
Fat 50  
Chicken  
 Muscle  15 
CAC 32 (2009)  
  
Liver  50  
Kidney  15  
Fat 50  
 
 
NEOMYCIN  (antimicrobial agent (مضادالميكروبات  
Acceptable Daily Intake 
(ADI)  0-60 μg/kg body weight  
Residue Definition  Neomycin 
Species Tissue MRL (μg/kg) Referance Notes 
Cattle  Muscle  500 CAC 23 (1999)  
  مواصفة  قياسية خليجية  GSO  2481/2019  
  
 
 
29 
 Liver  500 CAC 28 (2005)  
  
Kidney  10000   
Fat 500 CAC 23 (1999)  
  
Milk  1500  CAC 28 (2005)  
  
Chicken  
 Muscle  500 
CAC 23 (1999)  
  
Liver  500  
Kidney  10000   
Fat 500  
Eggs  500  
Duck  Muscle  500 
CAC 23 (1999)  
  
Liver  500  
Kidney  10000   
Fat 500  
Goat  Muscle  500 
CAC 23 (1999)  
  
Liver  500  
Kidney  10000   
 Fat 500   
Sheep  Muscle  500 
CAC 23 (1999)  
  
Liver  500  
Kidney  10000   
Fat 500  
Turkey  Muscle  500 
CAC 23 (1999)  
  
Liver  500  
Kidney  10000   
Fat 500  
 
 مواصفة  قياسية خليجية  GSO  2481/2019  
  
 
 
30 
 NICARBAZIN  (antiprotozoal agent   (مضادات الطفيليات  
Acceptable Daily Intake 
(ADI)  0-400 μg/kg body weight.  
Residue Definition  , N'-bis(4-nitropheyl)urea  
Species Tissue MRL (μg/kg) Referance Notes 
Chicken  Muscle  200 
CAC 23 (1999)  
 Broilers 
Liver  200 Broilers 
Kidney  200 Broilers 
Fat 200 Broilers 
 
 
PHOXIM  (insecticide (مبيد حشري  
Acceptable Daily Intake 
(ADI)  0-4 μg/kg body weight  
Residue Definition  Phoxim 
Species Tissue MRL (μg/kg) Referance Notes 
Goat  Muscle  50 
CAC 26 (2003)  
  
Liver  50  
Kidney  50  
Fat 400  
Sheep  Muscle  50 
CAC 2 6 (2003)  
  
Liver  50  
Kidney  50  
Fat 400  
 
 
Pirlimycin  (antimicrobial agent (مضادالميكروبات  
Acceptable Daily Intake 
(ADI)  0-8 μg/kg body weight  
Residue Definition  Pirlimycin 
Species Tissue MRL (μg/kg) Referance Notes 
Cattle  Muscle  100 
CAC 29 (2006)  
  
Liver  1000   
Kidney  400  مواصفة  قياسية خليجية  GSO  2481/2019  
  
 
 
31 
 Fat 100  
Milk  100 JECFA  evaluated the effect 
of pirlimycin residues on 
starter cultures and for this 
reason recommended an 
MRL of 100 μg/kg of milk. 
Codex Members may 
therefore adapt 
national/regional MRLs in 
order to address this 
technological aspect for 
trade of fresh liquid milk 
intended for processing 
using starter culture . 
 
 
PROGESTERONE  (production aid (مساعد انتاج  
Acceptable Daily Intake 
(ADI)  0-30 μg/kg body weight  
Residue Definition  Progesterone 
Spec ies  Tissue MRL (μg/kg) Referance Notes 
Cattle  Muscle  unnecessary  
CAC 21 (2005)  
 Residues resulting from the 
use of this substances as a 
growth promoter in 
accordance with good 
animal husbandry practice 
are unlikely to pose a 
hazard to human health .  Liver unnecessary  
Kidney  unnecessary  
Fat unnecessary  
 
RACTOPAMINE  (production aid (مساعد انتاج  
Acceptable Daily Intake 
(ADI)  0-30 μg/kg body weight  
Residue Definition  Ractopamine 
Species Tissue MRL (μg/kg) Referance Notes 
Cattle  Muscle  10 
CAC 35  (2012)  
  
Liver  40 
Kidney  90 
Fat 10 
 
 
 
 مواصفة  قياسية خليجية  GSO  2481/2019  
  
 
 
32 
 SARAFLOXACIN  (insecticide (مبيد حشري  
Acceptable Daily Intake 
(ADI)  0-0.3 μg/kg body weight  
Residue Definition  Sarafloxacin 
Species Tissue MRL (μg/kg) Referance Notes 
Chicken  Muscle  10 
CAC 24 (2001)  
  
Liver  80  
Kidney  80  
Fat 20  
Turkey  Muscle  10 
CAC 24 (2001)  
  
Liver  80  
Kidney  80  
Fat 20  
 
 
SPECTINOMYCIN  (antimicrobial agent (مضادالميكروبات  
Acceptable Daily Intake 
(ADI)  0-40 μg/kg body weight  
Residue Definition  Spectinomycin 
Species Tissue MRL (μg/kg) Referance Notes 
Cattle  Muscle  500 
CAC 23 (1999)  
  
Liver  2000   
Kidney  5000   
Fat 2000   
Milk 
μg/l 200  
Chicken  Muscle  500 
CAC 23 (1999)  
  
Liver  2000   
Kidney  5000   
Fat 2000   
Eggs  2000   
Sheep  Muscle  500 CAC 2 3 (1999)   مواصفة  قياسية خليجية  GSO  2481/2019  
  
 
 
33 
 Liver  2000    
Kidney  5000   
Fat 2000   
 
 
SPIRAMYCIN  (antimicrobial agent (مضادالميكروبات  
Acceptable Daily Intake 
(ADI)  0-50 μg/kg body weight  
Residue Definition  Cattle and chickens, sum of spiramycin and neospiramycin ;   
Species Tissue MRL (μg/kg) Referance Notes 
Cattle  Muscle  200 
CAC 22 (1997)  
  
Liver  600  
Kidney  300  
Fat 300  
Milk 
μg/l 200  
Chicken  Muscle  200 
CAC 22 (1997)  
  
Liver  600  
Kidney  800  
Fat 300  
 
 
 
SULFADIMIDINE  (antimicrobial agent (مضادالميكروبات  
Acceptable Daily Intake 
(ADI)  0-50 μg/kg body weight  
Residue Definition  Sulfadimidine 
Species Tissue MRL (μg/kg) Referance Notes 
Cattle  Milk 
μg/l 25 CAC 21 (1995)  
  
Not specified  Muscle  100 
CAC 21 (1995)   
Liver  100  
Kidney  100  
Fat 100  مواصفة  قياسية خليجية  GSO  2481/2019  
  
 
 
34 
  
TEFLUBENZURON  (insecticide    (مبيد حشري  
Acceptable Daily Intake 
(ADI)  0-5 μg/kg bw on the basis of a lower 95% confidence limit on 
the benchmark dose for a 10% response (BMDL10) of 0.54 
mg/kg bw per day for hepatocellular hypertrophy in male mice 
observed in  a carcinogenicity study, with application of an 
uncertainty factor of 100 to account for interspecies and 
intraspecies variability.  
Estimated Chronic 
Dietary Exposure  The EDI is 42.9 μg/person per day, on the basis of a 60 kg 
individual, which represents  approximately 14% of the upper 
bound of the ADI. The GECDE for the general population is 
1.6 μg/kg bw per day, which represents 31% of the upper 
bound of the ADI. The GECDE for children is 2.1 μg/kg bw 
per day, which represents 43% of the upper bound of t he ADI. 
The GECDE for infants is 0.9 μg/kg bw per day, which 
represents 18% of the upper bound of the ADI.  
Residue Definition  Teflubenzuron 
Species Tissue MRL (μg/kg) Referance Notes 
Salmon  Muscle  400 
CAC 40 (2017)  
  
Fillet  400 Muscle plus skin in na tural 
proportion  
 
TESTOSTERONE  (production aid (مساعد انتاج  
Acceptable Daily Intake 
(ADI)  0-2 μg/kg body weight  
Residue Definition  Testosterone 
Species Tissue MRL (μg/kg) Referance Notes 
Cattle  Muscle  unnecessary  
CAC 21 (1995)  Residues resulting from the 
use of this substances as a 
growth promoter in 
accordance with good 
animal husbandry practice 
are unlikely to pose a 
hazard to human health . Liver  unnecessary  
Kidney  unnecessary  
Fat unnecessary  
 
 
THIABENDAZOLE  (Anthelmintic agent    (مضاد الديدان  
Acceptable Daily Intake 
(ADI)  0-100 μg/kg body weight  
Residue Definition  Sum of thiabendazole and 5 -hydroxythiabendazole  
Species Tissue MRL (μg/kg) Referance Notes 
Cattle  Muscle  100 CAC 21 (1995)  The MRL also covers مواصفة  قياسية خليجية  GSO  2481/2019  
  
 
 
35 
 Liver  100  residues derived from feed 
containing the residues 
resulted from agricultural 
use. Kidney  100 
Fat 100 
Milk 
μg/l 100 
Goat  Muscle  100 
CAC 21 (1995)  
 The MRL also covers 
residues derived from feed 
containing the residues 
resulted from agricultural 
use. Liver  100 
Kidney  100 
Fat 100 
Milk 
μg/l 100 
Sheep  Muscle  100 
CAC 21 (1995)  
 The MRL also covers 
residues derived from feed 
containing the residues 
resulted from agricultural 
use. Liver  100 
Kidney  100 
Fat 100 
 
 
TILMICOSIN  (antimicrobia l agent (مضادالميكروبات  
Acceptable Daily Intake 
(ADI)  0-40 μg/kg body weight  
Residue Definition  Tilmicosin 
Species Tissue MRL (μg/kg) Referance Notes 
Cattle  Muscle  100 
CAC 23 (1999)  
  
Liver  1000  
Kidney  300 
Fat 100 
Chicken  Muscle  150 
CAC 34 (2011 ) 
  
Liver  2400 
Kidney  600 
Skin/ Fat 250 
Sheep  Muscle  100 
CAC 23 (1999)  
  
Liver  1000  
Kidney  300 
Fat 100 
Turkey  Muscle  100 
CAC 34 (2011)  
  
Liver  1200   
Kidney  1400   
Skin/Fat  250  
 
 
 مواصفة  قياسية خليجية  GSO  2481/2019  
  
 
 
36 
 TRENBOLONE  ACETATE  (Growth Promotin g Agent (محفز النمو  
Acceptable Daily Intake 
(ADI)  0-0.2 μg/kg body weight  
Residue Definition  Cattle muscle, beta -Trenbolone; Cattle liver, alpha -Trenbolone  
Species Tissue MRL (μg/kg) Referance Notes 
Cattle  Muscle  2 CAC 21 (1995)  
  
Liver  10 
 
 
TRICH LORFON  (Metrifonate ((insecticide    (مبيد حشري  
Acceptable Daily Intake 
(ADI)  0-2 μg/kg body weight  
Residue Definition  JECFA54 confirmed the MRL for cows’s milk and the guidance 
levels for muscle, liver, kidney and fat of cattle recommended 
(WHO TRS 900, 2001 )  
Species Tissue MRL (μg/kg) Referance Notes 
Cattle  Milk  50 CAC 2 9 (2006) 
  
 
TRICLABENDAZOLE  (Anthelmintic agent    (مضاد الديدان  
Acceptable Daily Intake 
(ADI)  0-3 μg/kg body weight  
Residue Definition  Ketotriclabnedazole 
Species Tissue MRL (μg/kg) Referance Notes 
Cattle  Muscle  250 
CAC 32 (2009)   
Liver  850 
Kidney  400 
Fat 100 
Sheep  Muscle  200 
CAC 32 (2009)   
Liver  300 
Kidney  200 
Fat 100 
 
 
TYLOSIN  (antimicrobial agent (مضادالميكروبات  
Acceptable Daily Intake 
(ADI)  0-30 μg/kg  bw based on a microbiological end -point derived 
from in vitro MIC susceptibility testing and faecal binding data 
(MICcalc = 1.698)  
Residue Definition  Tylosin A 
Species Tissue MRL (μg/kg) Referance Notes 
Cattle  Muscle  100 CAC 32 (2009)   مواصفة  قياسية خليجية  GSO  2481/2019  
  
 
 
37 
 Liver  100  
Kidney  100 
Fat 100 
Milk  100  
Chicken  Muscle  100 
CAC 32 (2009)  
  
Liver  100 
Kidney  100 
Skin/Fa
t 100 
Eggs  300  
 
 
ZERANOL  (Growth Promoting Agent (محفز النمو  
Acceptable Daily Intake 
(ADI)  0-0.5 μg/kg body weight  
Residue Definition  Zeranol 
Species Tissue MRL (μg/kg) Referance Notes 
Cattle  Muscle  2 CAC 21 (1995)  
  
Liver  10 
 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 مواصفة  قياسية خليجية  GSO  2481/2019  
  
 
 
38 
 References :  
 Codex  Alimentarius Commission (CAC), Maximum residue limits (MRLs) of 
veterinary drugs in food CX/MRL 2 -2018 . 
 