Designation of Substances Used as Ingredients of Agricultural Chemicals 
That Are Stipulated to be “Should Not be Detected” in Food 
 
 
In Japan, the Food Sanitation Act authorizes the Minister of Health, Labour 
and Welfare (MHLW) to establish residue standards (maximum residue 
limits: MRLs) for pesticides, feed additives, and veterinary drugs (hereafter 
referred to as “agricultural chemicals”) that may remain in foods. Any food 
for which standards are established pursuant to the provisions in the act is 
not permitted to be marketed in Japan unless it complies with the established 
standards. 
 
The Food Safety Commission of Japan (FSC) has recently conducted risk 
assessment for Nitarsone and concluded that an Acceptable Daily Intake 
(ADI) should not be established because the substance is likely to be genotoxic 
and carcinogenetic. 
 
Based on the conclusion of the FSC, the MHLW designates it as an ingredient 
of the agricultural chemicals that are stipulated to be "Should not be detected" 
in food.  
 