. /.WORLD TRADE
ORGANIZATIONG/SPS/N/CAN/83
28 April 2000
(00-1717)
Committee on Sanitary and Phytosanitary Measures Original:  English/
French
NOTIFICATION
1. Member to Agreement notifying:  CANADA
If applicable, name of local government involved:           
2. Agency responsible:  Department of Health
3. Products covered (provide tariff item number(s) as specified in national schedules
deposited with the WTO; ICS numbers may be provided in addition, where
applicable). ):  Aminopeptidase enzyme  Regions or countries likely to be affected, to the
extent relevant or practicable:
4. Title and number of pages of the notified document:  Proposed Amendment to the Food
and Drug Regulations (1097 – Am inopeptidase) (pages 1200-1203)
5. Description of content: Health Canada has received a submission to allow the use of
aminopeptidase enzyme from Lactococcus lactis in the production of cheese, dairy-based
flavouring preparations and food protein hydrolyzates.
Extensive studies have determined the safety and efficacy of aminopeptidase from
Lactococcus lactis for the proposed uses. The specifications for this enzyme conform to the
requirements for enzyme preparations in the Food Chemicals Codex 4th Edition.  This
enzyme has been approved for use in the United States since 1995.
The proposed amendments would permit the use of the aminopeptidase enzyme from
Lactococcus lactis  in combination with other permitted food enzymes to enhance the rate of
ripening in (named variety) cheese and to prev ent the formation of bitter off-flavours in the
production of dairy-based flavouring preparati ons and food protein hydrolysates. In these
applications, the aminopeptidase enzyme would be used at levels consistent with "Good
Manufacturing Practice".
6. Objective and rationale: [  X ] food safety,  [     ] animal health,  [     ] plant protection,
[    ] protect humans from animal/plant pest or disease, [     ] protect territory from
other damage from pests           
7. An international standard, guideline or recommendation does not exist [  X ].
If an international standard, guideline or recommendation exists, give the appropriate
reference and briefly identify deviations:           
8. Relevant documents and language(s) in which these are available:  Canada Gazette,
Part I, 15 April 2000 (Available in English and French)
9. Proposed date of adoption:  Not stated.
10. Proposed date of entry into force:  Not stated.G/SPS/N/CAN/83
Page 2
11. Final date for comments:  15 May 2000
Agency or authority designated to handle comments:  [     ] National notification
authority, [  X ] National enquiry point, or address, fax number and E-mail address (if
available) of other body:           
12. Texts available from: [     ] National notification authority, [  X ] National enquiry point
or address, fax number and E-mail address (if available) of other body:           