. /.WORLD TRADE
ORGANIZATIONG/SPS/N/CAN/108
16 May 2001
(01-2512)
Committee on Sanitary and Phytosanitary Measures Original:  English/
French
NOTIFICATION
1. Member to Agreement notifying:  CANADA
If applicable, name of local government involved:           
2. Agency responsible:  Department of Health
3. Products covered (provide tariff item number(s) as specified in national schedules
deposited with the WTO; ICS numbers may be provided in addition, where
applicable).  Regions or countries likely to be affected, to the extent relevant or
practicable:  Isoxaflutole
4. Title and number of pages of the notified document:  Proposed Amendment to the Food
and Drug Regulations (1219- Isoxaflutole) (pages 1589-1592)
5. Description of content:  Under authority of the Pest Control Products Ac t, the Pest
Management Regulatory Agency (PMRA), of Health Canada, has approved an application
for the registration of the pest control product (pesticide) isoxaflutole as a herbicide for the
control of barnyard grass, green foxtail, witchgrass, large crabgrass, smooth crabgrass,lamb’s-quarters, redroot pigweed, common ragweed, Eastern black nightshade, wormseed
mustard, wild mustard, velvetleaf, broadleaf plantain and dandelions in corn as a pre-
emergent treatment.  This proposed regulatory amendment would establish a Maximum
Residue Limit (MRL) under the Food and Drugs Act for residues of isoxaflutole and its
metabolites resulting from this use in corn, in order to permit the sale of food containing
these residues.  This proposed amendment would also establish MRLs in eggs; liver of
cattle and poultry; meat and meat by-products of cattle, hogs, horses, poultry and sheep; andmilk to cover residues in food derived from animals fed with crops treated with isoxaflutole.
After the review of all available data, the PM RA has determined that MRLs for isoxaflutole,
including its metabolites, of 0.5 parts per million (ppm) in liver of cattle, 0.3 ppm in liver of
poultry, 0.2 ppm in corn and meat of cattle, hogs, horses, poultry and sheep, 0.1 ppm in
meat by-products of cattle, hogs, horses, poultry and sheep, 0.02 ppm in milk and 0.01 ppmin eggs would not pose an unacceptable health risk to the public.
6. Objective and rationale: [  X ] food safety,  [     ] animal health,  [     ] plant protection,
[    ] protect humans from animal/plant pest or disease, [     ] protect territory from
other damage from pests           
7. An international standard, guideline or recommendation does not exist [     ].
If an international standard, guideline or recommendation exists, give the appropriate
reference and briefly identify deviations:  There are no Codex MRLs established. The
Canadian MRLs are harmonized with the US tolerances.G/SPS/N/CAN/108
Page 2
8. Relevant documents and language(s) in which these are available: :   Canada Gazette,
Part 1, 5 May, 2001 (Available in English and French)
9. Proposed date of adoption:  Not stated.
10. Proposed date of entry into force:  Not stated.
11. Final date for comments:  4 July 2001
Agency or authority designated to handle comments:  [     ] National notification
authority, [  X ] National enquiry point, or address, fax number and E-mail address (if
available) of other body:           
12. Texts available from: [     ] National notification authority, [  X ] National enquiry point
or address, fax number and E-mail address (if available) of other body:
Text also available on the internet at: http://canada.gc.ca/gazette/part1/pdf/g1-13518.pdf