section_path: Origin/Maize and teosinte
section_name: Maize and teosinte
paragraph_text: Maize and teosinte
  
  Maize is the domesticated variant of the four species of teosintes, which are its crop wild relatives. The teosinte origin theory was proposed by the Russian botanist Nikolai Ivanovich Vavilov in 1931, and the American Nobel Prize -winner George Beadle in 1932. The two plants have dissimilar appearance, maize having a single tall stalk with multiple leaves and teosinte being a short, bushy plant. The difference between the two is largely controlled by differences in just two genes, called grassy tillers-1 (gt1, A0A317YEZ1) and teosinte branched-1 (tb1, Q93WI2). In the late 1930s, Paul Mangelsdorf suggested that domesticated maize was the result of a hybridization event between an unknown wild maize and a species of Tripsacum, a related genus; this has been refuted by modern genetic testing.
  
  In 2004, John Doebley identified Balsas teosinte, Zea mays subsp. parviglumis, native to the Balsas River valley in Mexico's southwestern highlands, as the crop wild relative genetically most similar to modern maize. The middle part of the short Balsas River valley is the likely location of early domestication. Stone milling tools with maize residue have been found in an 8,700 year old layer of deposits in a cave not far from Iguala, Guerrero. Doebley and colleagues showed in 2002 that maize had been domesticated only once, about 9,000 years ago, and then spread throughout the Americas.
  
  Maize pollen dated to 7,300 years ago from San Andres, Tabasco has been found on the Caribbean coast. A primitive corn was being grown in southern Mexico, Central America, and northern South America 7,000 years ago. Archaeological remains of early maize ears, found at Guila Naquitz Cave in the Oaxaca Valley, are roughly 6,250 years old; the oldest ears from caves near Tehuacan, Puebla, are 5,450 years old.