section_path: History/Rome and Byzantine Empire
section_name: Rome and Byzantine Empire
paragraph_text: Rome and Byzantine Empire
  
  When Pergamon requested assistance in its conflict with the Seleucids, Rome intervened in Anatolia in the second century BC. Without an heir, Pergamum's king left the kingdom to Rome, which was annexed as province of Asia. Roman influence grew in Anatolia afterwards. Following Asiatic Vespers massacre, and Mithridatic Wars with Pontus, Rome emerged victorious. Around the 1st century BC, Rome expanded into parts of Pontus and Bithynia, while turning rest of Anatolian states into Roman satellites. Several conflicts with Parthians ensued, with peace and wars alternating.
  
  According to Acts of the Apostles, early Christian Church had significant growth in Anatolia because of St Paul's efforts. Letters from St. Paul in Anatolia comprise the oldest Christianliterature. According to extrabiblical traditions, the Assumption of Mary took place in Ephesus, where Apostle John was also present. Irenaeus writes of "the church of Ephesus, founded by Paul, with John continuing with them until the times of Trajan."
  
  The Byzantine Empire, also referred to as the Eastern Roman Empire, was the continuation of the Roman Empire centered in Constantinople during Late Antiquity and the Middle Ages. The eastern half of the Empire survived the conditions that caused the fall of the West in the 5th century AD, and continued to exist until the fall of Constantinople to the Ottoman Empire in 1453. During most of its existence, the empire remained the most powerful economic, cultural, and military force in the Mediterranean world. The term Byzantine Empire was only coined following the empire's demise; its citizens referred to the polity as the "Roman Empire" and to themselves as Romans. Due to the imperial seat's move from Rome to Byzantium, the adoption of Christianity as the state religion, and the predominance of Greek instead of Latin, modern historians continue to make a distinction between the earlier Roman Empire and the later Byzantine Empire.
  
  In the early Byzantine Empire period, the Anatolian coastal areas were Greek speaking. In addition to natives, interior Anatolia had diverse groups such as Goths, Celts, Persians and Jews. Interior Anatolia had been "heavily Hellenized". Anatolian languages eventually became extinct after Hellenization of Anatolia.
  
  Several ecumenical councils of the early Church were held in cities located in present-day Turkey, including the First Council of Nicaea (Iznik) in 325 (which resulted in the first uniform Christian doctrine, called the Nicene Creed), the First Council of Constantinople in 381, the Council of Ephesus in 431, and the Council of Chalcedon in 451.