section_path: Signs and symptoms/Ordinary/Confluent
section_name: Confluent
paragraph_text: Confluent
  
  Sometimes, the blisters merged into sheets, forming a confluent rash, which began to detach the outer layers of skin from the underlying flesh. Patients with confluent smallpox often remained ill even after scabs had formed over all the lesions. In one case series, the case-fatality rate in confluent smallpox was 62%.