section_path: Professional career/2022: Three major quarterfinals
section_name: 2022: Three major quarterfinals
paragraph_text: 2022: Three major quarterfinals
  
  At the Australian Open Sinner reached the quarterfinals of a major for the second time in his career, becoming the fifth Italian man to reach that stage in Melbourne. He then lost to fourth seed Stefanos Tsitsipas in straight sets.
  
  At the Miami Open, he saved three match points in the opening round against Emil Ruusuvuori and five match points against Pablo Carreño Busta to advance to the round of 16. He then defeated Nick Kyrgios but retired against Francisco Cerúndolo in the quarterfinals. In the Monte Carlo Masters, he again reached the quarterfinals after defeating fifth seed Andrey Rublev, before losing to second seed Alexander Zverev in a three-set and over three hour-long match. He again saved three match points in the opener at the Madrid Open against Tommy Paul to move to the second round. Next, he defeated Alex de Minaur for his 100th career win; he hit this milestone after 147 matches (100–47) on Tour, which was a faster rate than everyone in the Top 10 besides Rafael Nadal (100–37) and Novak Djokovic (100–43). He was defeated in the third round by Félix Auger-Aliassime.
  
  At the French Open, he retired in the fourth round against Andrey Rublev after sustaining a knee injury.
  
  At the Eastbourne International, Sinner suffered his first opening round loss of the year after losing to Tommy Paul in three sets. At the 2022 Wimbledon Championships, he recorded his first win at this Major over Stan Wawrinka. He then beat Mikael Ymer, John Isner, and Carlos Alcaraz to reach his third career Grand Slam quarterfinal. He lost to top seed and eventual champion Novak Djokovic in five sets in the quarterfinals, after being two sets to love up.
  
  At the Croatia Open, Sinner defeated Carlos Alcaraz in the final to win his first clay court title. In Montreal, he lost to eventual champion Pablo Carreño Busta in the third round. Sinner's loss guaranteed a maiden Masters 1000 finalist from his half of the draw. At the Cincinnati Masters, he lost in the third round to Félix Auger-Aliassime after being up a set, a break, and 2 match points.
  
  Seeded 11th at the US Open, he reached the fourth round after defeating Brandon Nakashima in four sets. Next, he defeated Ilya Ivashka in a five set match lasting close to four hours to reach the quarterfinals for the first time at this Major. He became the youngest player to reach the quarterfinals of all four Grand Slam tournaments since Novak Djokovic in 2007–08. He lost to Carlos Alcaraz in a five-set match that lasted 5 hours and 15 minutes; the match set the record as the latest finish (at 2:50 am EST) and second longest match in US Open history. Sinner held a match point while serving up 5–4 in the 4th set, but ended up losing the set 5–7.
  
  In September, during the Davis Cup Finals after Matteo Berrettini won his singles match against Argentina, Sinner won the second match (best of three matches) and thus secured a place for Italy's Davis Cup team at the Final 8 of the Davis Cup Finals. Following close to a month break due to an injury sustained in the semifinal at the 2022 Sofia Open he returned to the 2022 Erste Bank Open in Vienna and reached also the quarterfinals losing to top seed and eventual champion Daniil Medvedev. In his next tournament, the 2022 Rolex Paris Masters, he lost in the first round to qualifier Marc-Andrea Huesler.
  
  Sinner finished the year ranked 15th in the world, one space ahead of countryman Matteo Berrettini.
  
  At the Australian Open Sinner reached the quarterfinals of a major for the second time in his career, becoming the fifth Italian man to reach that stage in Melbourne. He then lost to fourth seed Stefanos Tsitsipas in straight sets.
  
  At the Miami Open, he saved three match points in the opening round against Emil Ruusuvuori and five match points against Pablo Carreño Busta to advance to the round of 16. He then defeated Nick Kyrgios but retired against Francisco Cerúndolo in the quarterfinals. In the Monte Carlo Masters, he again reached the quarterfinals after defeating fifth seed Andrey Rublev, before losing to second seed Alexander Zverev in a three-set and over three hour-long match. He again saved three match points in the opener at the Madrid Open against Tommy Paul to move to the second round. Next, he defeated Alex de Minaur for his 100th career win; he hit this milestone after 147 matches (100–47) on Tour, which was a faster rate than everyone in the Top 10 besides Rafael Nadal (100–37) and Novak Djokovic (100–43). He was defeated in the third round by Félix Auger-Aliassime.
  
  At the French Open, he retired in the fourth round against Andrey Rublev after sustaining a knee injury.
  
  At the Eastbourne International, Sinner suffered his first opening round loss of the year after losing to Tommy Paul in three sets. At the 2022 Wimbledon Championships, he recorded his first win at this Major over Stan Wawrinka. He then beat Mikael Ymer, John Isner, and Carlos Alcaraz to reach his third career Grand Slam quarterfinal. He lost to top seed and eventual champion Novak Djokovic in five sets in the quarterfinals, after being two sets to love up.
  
  At the Croatia Open, Sinner defeated Carlos Alcaraz in the final to win his first clay court title. In Montreal, he lost to eventual champion Pablo Carreño Busta in the third round. Sinner's loss guaranteed a maiden Masters 1000 finalist from his half of the draw. At the Cincinnati Masters, he lost in the third round to Félix Auger-Aliassime after being up a set, a break, and 2 match points.
  
  Seeded 11th at the US Open, he reached the fourth round after defeating Brandon Nakashima in four sets. Next, he defeated Ilya Ivashka in a five set match lasting close to four hours to reach the quarterfinals for the first time at this Major. He became the youngest player to reach the quarterfinals of all four Grand Slam tournaments since Novak Djokovic in 2007–08. He lost to Carlos Alcaraz in a five-set match that lasted 5 hours and 15 minutes; the match set the record as the latest finish (at 2:50 am EST) and second longest match in US Open history. Sinner held a match point while serving up 5–4 in the 4th set, but ended up losing the set 5–7.
  
  In September, during the Davis Cup Finals after Matteo Berrettini won his singles match against Argentina, Sinner won the second match (best of three matches) and thus secured a place for Italy's Davis Cup team at the Final 8 of the Davis Cup Finals. Following close to a month break due to an injury sustained in the semifinal at the 2022 Sofia Open he returned to the 2022 Erste Bank Open in Vienna and reached also the quarterfinals losing to top seed and eventual champion Daniil Medvedev. In his next tournament, the 2022 Rolex Paris Masters, he lost in the first round to qualifier Marc-Andrea Huesler.
  
  Sinner finished the year ranked 15th in the world, one space ahead of countryman Matteo Berrettini.