Bless  v. (past and past part. Blessed, poet. Blest) 1 ask god to look favourably on, esp. By making the sign of the cross over. 2 consecrate (food etc.). 3 glorify (god). 4 attribute one's good luck to (stars etc.); thank. 5 (usu. In passive) make happy or successful (blessed with children).  bless me (or my soul) exclamation of surprise etc. Bless you! Exclamation of endearment, gratitude, etc., or to a person who has just sneezed. [old english]