All in all, fenbendazole presents a nuanced narrative in the context of #Oncology. While its established safety profile, moderate cytotoxic effects, and ability to disrupt microtubules make it an intriguing candidate for repurposing, significant limitations temper its potential as an anticancer agent. Preclinical studies have shown that fenbendazole can inhibit cancer cell proliferation, induce apoptosis, and target metabolic vulnerabilities, particularly in hypoxic or chemoresistant environments. However, its poor bioavailability, low systemic absorption, and limited in vivo efficacy significantly restrict its therapeutic value in its current form./44
#Oncology