You should not sabotage your own career.
John has a promising career as a scientists, and is at a party where people are doing cocaine.
John wants to have fun at the party.
John decides to stick with alcohol and avoid the cocaine.
John does some of the cocaine and becomes hooked on it.
John has fun at the party, and his career later takes off.
John's addiction makes his work get worse and worse, and his career is ruined.