Economic fears and 'Medicare for All': Here are the business issues to watch in the third Democratic debate
Democratic presidential hopefuls (fromL) US Senator from New Jersey Cory Booker, US Senator from California Kamala Harris and former Vice President Joe Biden applaud ahead of the second round of the second Democratic primary debate of the 2020 presidential campaign season hosted by CNN at the Fox Theatre in Detroit, Michigan on July 31, 2019. Jim Watson | AFP | Getty Images

For the 10 Democrats who have made it to the third presidential debate, the biggest target may still be President Donald Trump. But the candidates will likely also spend more time staking out their competing visions of the future of American industries, and the government's role in shaping them. One big showdown to watch on business and economic issues: Joe Biden and Elizabeth Warren, two of the three leading Democratic presidential candidates, are finally set to square off on the debate stage. Biden and Warren had clashed long before they became rivals in the 2020 race. And there are hints that they could butt heads Thursday night on health care, corporate money and other issues. Warren, who has supplied a steady stream of policy plans throughout her campaign, frames herself as a progressive capitalist who has the guts and the political wherewithal to take on the big banks and powerful corporations. Biden, who has maintained a steady lead in the polls since he launched his campaign, is making more moderate appeals and touting his track record as former President Barack Obama's right-hand man.

To Republicans, though, they both look like radicals when it comes to business and the economy, said Matt Gorman, a former aide to presidential candidates Mitt Romney and Jeb Bush. "A relative centrist compared to [Vermont Sen.] Bernie Sanders" — a top candidate who calls himself a democratic socialist — "is pretty damn far left," Gorman said. South Bend, Indiana, Mayor Pete Buttigieg, Sen. Kamala Harris of California, entrepreneur Andrew Yang, New Jersey Sen. Cory Booker, former Housing and Urban Development Secretary Julian Castro, former Texas Rep. Beto O'Rourke and Minnesota Sen. Amy Klobuchar are also slated to join the fray in the debate in Houston. It will be broadcast by ABC News on Thursday night from 8 p.m. ET to 11 p.m. ET. Here are the top business issues that could be in play at Thursday night:

Economic slowdown

watch now

Money in politics

Warren is sending chills down the spines of Wall Street executives, CNBC's Jim Cramer said Tuesday. More and more, Cramer said, he's hearing people on Wall Street saying, "She's got to be stopped." Warren, who has been climbing in public opinion polls, took that news as a badge of honor. "I'm Elizabeth Warren and I approve this message," she tweeted in response. Warren TWEET Biden, on the other hand, was headed to Wall Street for multiple fundraisers just last week. Biden's draw for the influence industry was strong enough that his campaign officials had to try to limit his interactions with lobbyists at fundraising events. Biden, a multidecade Washington veteran, has been able to raise a lot of money in a short time. But his campaign donors could become a sticking point in the debate against Warren and Sanders, who have sworn off top-dollar fundraisers. "Bernie will continue focusing on fundamentally changing our economy to work for everyone, and he will aggressively challenge dishonest right-wing attacks and corporate-sponsored talking points," his campaign said in a statement. "He's the strongest candidate to take on a rigged economy because he doesn't take its money and he's building a grassroots movement fueled by small-dollar donations." CNBC asked the campaigns of all 10 participants about the top business or economic issues they hope to cover in the debate. Only Sanders' and Yang's campaigns responded. "I think it's reasonable to ask what Wall Street has done lately to promote, or even advocate, the national interest," Galston said. "I think the reality of the current situation is that the leading candidates all have enough money to run their campaigns as they wish," he said, adding that Biden would not be well-served to become "publicly identified as Wall Street's favorite candidate."

Trade

Health care

Health care was a front-burner issue in the first two Democratic debates. It probably will be in Houston, too. All Democrats want to find ways to expand health-care coverage for more Americans. But there are huge chasms of difference between them about how to achieve that goal. Sanders has long advocated a government-run program — "Medicare for All" — that applies to everyone. His proposal, currently a bill that has no chance of passing the Republican-controlled Senate, would widen the types of coverage available, as well as push private insurers out of the Medicare mix in favor of a single-payer model. His bill was endorsed by Sen. Kirsten Gillibrand of New York, who dropped out of the 2020 race late last month. Warren, too, endorsed Sanders' overhaul plan. "I'm with Bernie on Medicare for All," she said at the first Democratic debate. Harris had once signaled as a presidential candidate that she wants to end private insurance. Others have not gone to such lengths. Klobuchar has supported a public option, for instance. Biden wants a "Medicare-like public option" that has "premium-free access" for people who would qualify for Medicaid but live in states where where governments have not expanded access to the insurance program for low-income people. — CNBC's John Schoen, Sunny Kim and Jacob Pramuk contributed to this report.