Take the following as truth: There are inherent differences between the use of a NOEC or LOEC derived from hypothesis testing to estimate a safe concentration, and the use of a LC, EC, IC, or other point estimates derived from curve fitting, interpolation, etc.
Then the following statement: "The NOEC or LOEC derived from hypothesis testing is far more reliable than using LC, EC, IC, or other types of estimates using interpolation." is true, false, or inconclusive?