I want to know the answer to the following question:
What does the manner of DNA storage on the histone and the chemical modifications of the histone itself regulate?
All the background I'm provided with is that "In addition to genes, eukaryotic chromosomes contain sequences involved in ensuring that the DNA is copied without degradation of end regions and sorted into daughter cells during cell division: replication origins, telomeres and the centromere.:4.2 Replication origins are the sequence regions where DNA replication is initiated to make two copies of the chromosome.". Is that enough to answer the question?