{"instruction": "You are an expert in event extraction. Please extract events from the input that conform to the schema definition. Return an empty list for events that do not exist, and return NAN for arguments that do not exist. If an argument has multiple values, please return a list. Respond in the format of a JSON string.", "schema": [{"event_type": "adverse event", "trigger": true, "arguments": ["Treatment.Time_elapsed", "Subject", "Subject.Age", "Subject.Population", "Subject.Race", "Treatment.Freq", "Subject.Disorder", "Subject.Gender", "Treatment.Duration", "Combination.Drug", "Treatment.Drug", "Treatment", "Treatment.Dosage", "Treatment.Route", "Effect", "Treatment.Disorder"]}, {"event_type": "potential therapeutic event", "trigger": true, "arguments": ["Effect", "Treatment.Route", "Treatment.Freq", "Treatment.Disorder", "Subject.Gender", "Treatment", "Treatment.Drug", "Treatment.Dosage", "Subject.Race", "Treatment.Time_elapsed", "Subject", "Treatment.Duration", "Subject.Disorder"]}], "input": "CONCLUSION: Hypersensitivity reaction should be considered in patients who develop recurrent eosinophilia and deterioration of pulmonary function following the use of tobramycin by inhalation or by intravenous administration."}
{"adverse event": [{"trigger": "develop ", "arguments": {"Treatment.Time_elapsed": "NAN", "Subject": "patients", "Subject.Age": "NAN", "Subject.Population": "NAN", "Subject.Race": "NAN", "Treatment.Freq": "NAN", "Subject.Disorder": "NAN", "Subject.Gender": "NAN", "Treatment.Duration": "NAN", "Combination.Drug": "NAN", "Treatment.Drug": "tobramycin", "Treatment": "use of tobramycin by inhalation or by intravenous administration", "Treatment.Dosage": "NAN", "Treatment.Route": ["inhalation", "intravenous administration."], "Effect": "recurrent eosinophilia and deterioration of pulmonary function", "Treatment.Disorder": "NAN"}}], "potential therapeutic event": []}