{"instruction": "You are an expert in named entity recognition. Please extract entities that match the schema definition from the input. Return an empty list if the entity type does not exist. Please respond in the format of a JSON string.", "schema": ["DNA", "cell type", "protein", "cell line", "RNA"], "input": "In three unrelated Japanese children with combined pituitary hormone deficiency , we identified three point mutations in the Pit-1 gene , Pro24Leu , Arg143Gln , and Arg271Trp , located on the major transactivation region , POU-specific domain , and POU-homeodomain , respectively."}
{"DNA": ["Pit-1 gene", "Pro24Leu", "Arg143Gln", "Arg271Trp", "major transactivation region", "POU-specific domain", "POU-homeodomain"], "cell type": [], "protein": ["Pit-1"], "cell line": [], "RNA": []}