{"instruction": "You are an expert in event extraction. Please extract events from the input that conform to the schema definition. Return an empty list for events that do not exist, and return NAN for arguments that do not exist. If an argument has multiple values, please return a list. Respond in the format of a JSON string.", "schema": [{"event_type": "potential therapeutic event", "trigger": true, "arguments": ["Subject.Disorder", "Treatment.Freq", "Subject", "Treatment.Time_elapsed", "Combination.Drug", "Subject.Age", "Subject.Population", "Treatment.Dosage", "Treatment.Route", "Treatment.Disorder", "Treatment.Duration", "Subject.Gender", "Subject.Race", "Effect"]}, {"event_type": "adverse event", "trigger": true, "arguments": ["Subject.Race", "Subject.Age", "Subject.Disorder", "Treatment", "Treatment.Dosage", "Subject.Gender", "Treatment.Duration", "Combination.Drug", "Treatment.Route", "Subject", "Effect", "Treatment.Drug", "Treatment.Freq", "Treatment.Time_elapsed", "Treatment.Disorder", "Subject.Population"]}], "input": "Agranulocytosis is a rare adverse effect associated with prolonged vancomycin therapy, and is potentially serious, especially in end stage renal disease (ESRD) patients."}
{"potential therapeutic event": [], "adverse event": [{"trigger": "associated ", "arguments": {"Subject.Race": "NAN", "Subject.Age": "NAN", "Subject.Disorder": "NAN", "Treatment": "prolonged vancomycin therapy", "Treatment.Dosage": "NAN", "Subject.Gender": "NAN", "Treatment.Duration": "prolonged", "Combination.Drug": "NAN", "Treatment.Route": "NAN", "Subject": "end stage renal disease (ESRD) patients", "Effect": "Agranulocytosis", "Treatment.Drug": "vancomycin", "Treatment.Freq": "NAN", "Treatment.Time_elapsed": "NAN", "Treatment.Disorder": "end stage renal disease (ESRD)", "Subject.Population": "NAN"}}]}