{"instruction": "You are an expert in named entity recognition. Please extract entities that match the schema definition from the input. Return an empty list if the entity type does not exist. Please respond in the format of a JSON string.", "schema": ["protein", "DNA", "RNA", "cell type", "cell line"], "input": "To establish a model for 1,25-(OH)2D3 regulation of human monocyte monokine synthesis , three human cell lines ( U-937 , THP-1 , and HL-60 ) were examined for: 1) the presence of functional 1,25-(OH)2D3 receptors; 2) the accumulation of interleukin-1 beta ( IL-1 beta ) mRNA and IL-1 beta protein in response to lipopolysaccharide ( LPS ); and 3) the regulation of this response by 1,25-(OH)2D3 ."}
{"protein": ["interleukin-1 beta", "IL-1 beta", "IL-1 beta protein"], "DNA": [], "RNA": ["interleukin-1 beta ( IL-1 beta ) mRNA"], "cell type": [], "cell line": ["human cell lines", "U-937", "THP-1", "HL-60"]}