{"instruction": "You are an expert in event extraction. Please extract events from the input that conform to the schema definition. Return an empty list for events that do not exist, and return NAN for arguments that do not exist. If an argument has multiple values, please return a list. Respond in the format of a JSON string.", "schema": [{"event_type": "potential therapeutic event", "trigger": true, "arguments": ["Subject.Race", "Treatment.Disorder", "Subject.Gender", "Effect", "Treatment.Dosage", "Treatment.Time_elapsed", "Treatment", "Treatment.Duration", "Treatment.Route", "Treatment.Freq"]}, {"event_type": "adverse event", "trigger": true, "arguments": ["Subject.Race", "Effect", "Treatment.Time_elapsed", "Subject.Gender", "Treatment.Dosage", "Subject", "Subject.Age", "Treatment.Drug", "Combination.Drug", "Treatment.Freq", "Treatment.Disorder", "Subject.Disorder", "Treatment.Route", "Treatment.Duration", "Treatment", "Subject.Population"]}], "input": "Seizures occurred in two patients with probable Alzheimer's disease who were receiving long-term treatment with metrifonate, an irreversible acetylcholinesterase inhibitor."}
{"potential therapeutic event": [], "adverse event": [{"trigger": "occurred ", "arguments": {"Subject.Race": "NAN", "Effect": "Seizures", "Treatment.Time_elapsed": "NAN", "Subject.Gender": "NAN", "Treatment.Dosage": "NAN", "Subject": "two patients with probable Alzheimer's disease", "Subject.Age": "NAN", "Treatment.Drug": "metrifonate", "Combination.Drug": "NAN", "Treatment.Freq": "NAN", "Treatment.Disorder": "Alzheimer's disease", "Subject.Disorder": "NAN", "Treatment.Route": "NAN", "Treatment.Duration": "NAN", "Treatment": "long-term treatment with metrifonate", "Subject.Population": "two"}}]}