{"instruction": "You are an expert in event argument extraction. Please extract event arguments and their roles from the input that conform to the schema definition, which already includes event trigger words. If an argument does not exist, return NAN or an empty dictionary. Please respond in the format of a JSON string.", "schema": [{"event_type": "potential therapeutic event", "arguments": ["Treatment.Freq", "Treatment.Drug", "Effect", "Treatment.Dosage", "Treatment", "Subject.Gender", "Subject", "Treatment.Time_elapsed", "Treatment.Duration", "Treatment.Disorder", "Treatment.Route", "Combination.Drug", "Subject.Race", "Subject.Disorder", "Subject.Age", "Subject.Population"]}], "input": "We review the literature on previously reported cases of cutaneous necrosis after injection of standard interferon alfa or pegylated interferon alfa-2b and discuss the different pathophysiologic mechanisms that might be involved."}
{"potential therapeutic event": []}