{"instruction": "You are an expert in named entity recognition. Please extract entities that match the schema definition from the input. Return an empty list if the entity type does not exist. Please respond in the format of a JSON string.", "schema": ["Chemical"], "input": "In vivo , the ratio of area under the concentration - time curve ( AUC ) ( brain ) to AUC ( plasma ) ( K ( p ) ) of dabrafenib after an i . v . dose ( 2 . 5 mg / kg ) was 0 . 023 , which increased by 18 - fold in Mdr1 a / b ( - / - ) Bcrp1 ( - / - ) mice to 0 . 42 ."}
{"Chemical": ["dabrafenib"]}