{"instruction": "You are an expert in event argument extraction. Please extract event arguments and their roles from the input that conform to the schema definition, which already includes event trigger words. If an argument does not exist, return NAN or an empty dictionary. Please respond in the format of a JSON string.", "schema": [{"event_type": "adverse event", "arguments": ["Effect", "Subject.Gender", "Subject.Disorder", "Treatment.Time_elapsed", "Treatment", "Treatment.Freq", "Combination.Drug", "Treatment.Dosage", "Subject.Age", "Treatment.Route", "Treatment.Disorder", "Subject", "Treatment.Drug", "Subject.Population", "Treatment.Duration", "Subject.Race"]}], "input": "This report describes a 13-year-old female with a right frontal high-grade glioma and complex partial seizures who developed localized purpura after 23 months of lamotrigine monotherapy."}
{"adverse event": [{"Effect": "localized purpura", "Subject.Gender": "female", "Subject.Disorder": "right frontal high-grade glioma", "Treatment.Time_elapsed": "NAN", "Treatment": "23 months of lamotrigine monotherapy", "Treatment.Freq": "NAN", "Combination.Drug": "NAN", "Treatment.Dosage": "NAN", "Subject.Age": "13-year-old", "Treatment.Route": "NAN", "Treatment.Disorder": ["23 months", "complex partial seizures"], "Subject": "a 13-year-old female with a right frontal high-grade glioma and complex partial seizures", "Treatment.Drug": "lamotrigine", "Subject.Population": "NAN", "Treatment.Duration": "NAN", "Subject.Race": "NAN"}]}