{"instruction": "You are an expert in event extraction. Please extract events from the input that conform to the schema definition. Return an empty list for events that do not exist, and return NAN for arguments that do not exist. If an argument has multiple values, please return a list. Respond in the format of a JSON string.", "schema": [{"event_type": "adverse event", "trigger": true, "arguments": ["Treatment.Disorder", "Subject.Population", "Subject", "Treatment.Dosage", "Subject.Disorder", "Effect", "Subject.Race", "Treatment.Drug", "Treatment.Freq", "Subject.Age", "Treatment.Time_elapsed", "Treatment", "Treatment.Route", "Combination.Drug"]}, {"event_type": "potential therapeutic event", "trigger": true, "arguments": ["Treatment.Dosage", "Subject.Gender", "Subject.Population", "Subject.Disorder", "Treatment.Drug", "Treatment", "Combination.Drug", "Effect", "Subject", "Subject.Race", "Treatment.Duration", "Treatment.Route"]}], "input": "Post marketing studies of Interferon-beta (IFN beta) therapy in multiple sclerosis (MS) have demonstrated surprisingly high rates of hepatotoxicity."}
{"adverse event": [{"trigger": "demonstrated ", "arguments": {"Treatment.Disorder": "NAN", "Subject.Population": "NAN", "Subject": "NAN", "Treatment.Dosage": "NAN", "Subject.Disorder": "NAN", "Effect": "hepatotoxicity", "Subject.Race": "NAN", "Treatment.Drug": "Interferon-beta (IFN beta)", "Treatment.Freq": "NAN", "Subject.Age": "NAN", "Treatment.Time_elapsed": "NAN", "Treatment": "Interferon-beta", "Treatment.Route": "NAN", "Combination.Drug": "NAN"}}], "potential therapeutic event": []}