{"instruction": "You are an expert in event argument extraction. Please extract event arguments and their roles from the input that conform to the schema definition, which already includes event trigger words. If an argument does not exist, return NAN or an empty dictionary. Please respond in the format of a JSON string.", "schema": [{"event_type": "adverse event", "arguments": ["Subject.Population", "Subject", "Subject.Race", "Treatment.Freq", "Treatment.Dosage", "Treatment", "Treatment.Drug", "Combination.Drug", "Treatment.Route", "Treatment.Duration", "Treatment.Time_elapsed", "Subject.Age", "Effect", "Treatment.Disorder"]}], "input": "During administration of chemotherapy, the patient progressively developed a complex association of Beau's lines, transverse melanonychia, Muehrcke's lines, and diffuse hyperpigmentation of the skin."}
{"adverse event": [{"Subject.Population": "NAN", "Subject": "patient", "Subject.Race": "NAN", "Treatment.Freq": "NAN", "Treatment.Dosage": "NAN", "Treatment": "chemotherapy", "Treatment.Drug": "NAN", "Combination.Drug": "NAN", "Treatment.Route": "chemotherapy", "Treatment.Duration": "NAN", "Treatment.Time_elapsed": "NAN", "Subject.Age": "NAN", "Effect": "a complex association of Beau's lines, transverse melanonychia, Muehrcke's lines, and diffuse hyperpigmentation of the skin", "Treatment.Disorder": "NAN"}]}