{"instruction": "You are an expert in event extraction. Please extract events from the input that conform to the schema definition. Return an empty list for events that do not exist, and return NAN for arguments that do not exist. If an argument has multiple values, please return a list. Respond in the format of a JSON string.", "schema": [{"event_type": "potential therapeutic event", "trigger": true, "arguments": ["Combination.Drug", "Subject.Disorder", "Treatment.Disorder", "Treatment.Freq", "Treatment.Duration", "Treatment.Time_elapsed", "Treatment.Dosage", "Subject.Race", "Subject.Population", "Effect", "Subject"]}, {"event_type": "adverse event", "trigger": true, "arguments": ["Subject", "Subject.Disorder", "Treatment.Freq", "Treatment.Disorder", "Treatment.Time_elapsed", "Treatment.Duration", "Treatment", "Subject.Population", "Treatment.Dosage", "Effect", "Subject.Race", "Subject.Gender", "Subject.Age", "Combination.Drug", "Treatment.Route", "Treatment.Drug"]}], "input": "Zoledronic acid-induced severe hypocalcaemia in a prostate cancer patient with extensive osteoblastic bone metastases."}
{"potential therapeutic event": [], "adverse event": [{"trigger": "induced ", "arguments": {"Subject": "prostate cancer patient with extensive osteoblastic bone metastases", "Subject.Disorder": "NAN", "Treatment.Freq": "NAN", "Treatment.Disorder": ["prostate cancer", "extensive osteoblastic bone metastases"], "Treatment.Time_elapsed": "NAN", "Treatment.Duration": "NAN", "Treatment": "Zoledronic acid", "Subject.Population": "NAN", "Treatment.Dosage": "NAN", "Effect": "severe hypocalcaemia", "Subject.Race": "NAN", "Subject.Gender": "NAN", "Subject.Age": "NAN", "Combination.Drug": "NAN", "Treatment.Route": "NAN", "Treatment.Drug": "Zoledronic acid"}}]}