{"instruction": "You are an expert in event extraction. Please extract events from the input that conform to the schema definition. Return an empty list for events that do not exist, and return NAN for arguments that do not exist. If an argument has multiple values, please return a list. Respond in the format of a JSON string.", "schema": [{"event_type": "potential therapeutic event", "trigger": true, "arguments": ["Subject.Race", "Effect", "Combination.Drug", "Treatment.Dosage", "Treatment.Drug", "Subject", "Subject.Disorder", "Subject.Population", "Treatment.Route", "Treatment.Duration", "Subject.Gender", "Subject.Age", "Treatment.Freq"]}, {"event_type": "adverse event", "trigger": true, "arguments": ["Treatment", "Treatment.Drug", "Treatment.Dosage", "Treatment.Duration", "Combination.Drug", "Treatment.Time_elapsed", "Effect", "Treatment.Disorder", "Subject.Gender", "Subject", "Treatment.Freq", "Subject.Population", "Treatment.Route", "Subject.Age", "Subject.Disorder"]}], "input": "The most serious dental side effect of bisphosphonate treatment (particularly when it is administered intravenously) is, paradoxically, osteonecrosis of the mandible or the maxilla represented by exposed nonhealing bone."}
{"potential therapeutic event": [], "adverse event": [{"trigger": "side effect ", "arguments": {"Treatment": "bisphosphonate treatment (particularly when it is administered intravenously)", "Treatment.Drug": "bisphosphonate", "Treatment.Dosage": "NAN", "Treatment.Duration": "NAN", "Combination.Drug": "NAN", "Treatment.Time_elapsed": "NAN", "Effect": "osteonecrosis of the mandible or the maxilla represented by exposed nonhealing bone", "Treatment.Disorder": "NAN", "Subject.Gender": "NAN", "Subject": "NAN", "Treatment.Freq": "NAN", "Subject.Population": "NAN", "Treatment.Route": "intravenously", "Subject.Age": "NAN", "Subject.Disorder": "NAN"}}]}