{"instruction": "You are an expert in event extraction. Please extract events from the input that conform to the schema definition. Return an empty list for events that do not exist, and return NAN for arguments that do not exist. If an argument has multiple values, please return a list. Respond in the format of a JSON string.", "schema": [{"event_type": "adverse event", "trigger": true, "arguments": ["Effect", "Subject.Race", "Treatment", "Combination.Drug", "Treatment.Disorder", "Treatment.Time_elapsed", "Subject.Population", "Treatment.Drug", "Treatment.Route", "Subject.Age", "Treatment.Dosage", "Subject.Disorder", "Subject.Gender", "Treatment.Freq"]}, {"event_type": "potential therapeutic event", "trigger": true, "arguments": ["Treatment.Time_elapsed", "Subject.Age", "Combination.Drug", "Subject", "Effect", "Treatment", "Treatment.Disorder", "Treatment.Dosage", "Treatment.Duration", "Subject.Population", "Subject.Gender", "Treatment.Drug", "Treatment.Freq"]}], "input": "This severe illness was likely caused by minocycline, and we speculate that minocycline may have acted as a superantigen, causing lymphocyte over-activation and massive cytokine release."}
{"adverse event": [{"trigger": "caused ", "arguments": {"Effect": "severe illness", "Subject.Race": "NAN", "Treatment": "minocycline", "Combination.Drug": "NAN", "Treatment.Disorder": "NAN", "Treatment.Time_elapsed": "NAN", "Subject.Population": "NAN", "Treatment.Drug": "minocycline", "Treatment.Route": "NAN", "Subject.Age": "NAN", "Treatment.Dosage": "NAN", "Subject.Disorder": "NAN", "Subject.Gender": "NAN", "Treatment.Freq": "NAN"}}], "potential therapeutic event": []}