{"instruction": "You are an expert in event argument extraction. Please extract event arguments and their roles from the input that conform to the schema definition, which already includes event trigger words. If an argument does not exist, return NAN or an empty dictionary. Please respond in the format of a JSON string.", "schema": [{"event_type": "adverse event", "arguments": ["Treatment.Disorder", "Subject.Population", "Treatment", "Treatment.Time_elapsed", "Treatment.Freq", "Subject.Disorder", "Treatment.Drug", "Treatment.Dosage", "Subject.Gender", "Subject.Age", "Subject", "Combination.Drug", "Subject.Race"]}], "input": "Peculiar nail-changes in a 70-year-old woman with rheumatoid arthritis occurring after approximately 1 year of penicillamine treatment are described."}
{"adverse event": [{"Treatment.Disorder": "rheumatoid arthritis", "Subject.Population": "NAN", "Treatment": "penicillamine", "Treatment.Time_elapsed": "1 year", "Treatment.Freq": "NAN", "Subject.Disorder": "NAN", "Treatment.Drug": "penicillamine", "Treatment.Dosage": "NAN", "Subject.Gender": "woman", "Subject.Age": "70-year-old", "Subject": "a 70-year-old woman with rheumatoid arthritis", "Combination.Drug": "NAN", "Subject.Race": "NAN"}]}