{"instruction": "You are an expert in event extraction. Please extract events from the input that conform to the schema definition. Return an empty list for events that do not exist, and return NAN for arguments that do not exist. If an argument has multiple values, please return a list. Respond in the format of a JSON string.", "schema": [{"event_type": "potential therapeutic event", "trigger": true, "arguments": ["Treatment.Time_elapsed", "Subject.Race", "Treatment.Dosage", "Effect", "Subject.Age", "Treatment", "Treatment.Drug", "Treatment.Duration", "Treatment.Freq", "Subject.Gender", "Subject.Population", "Combination.Drug", "Treatment.Route"]}, {"event_type": "adverse event", "trigger": true, "arguments": ["Subject.Gender", "Treatment.Drug", "Subject.Population", "Treatment", "Subject.Disorder", "Treatment.Disorder", "Subject.Age", "Treatment.Route", "Treatment.Dosage", "Effect", "Treatment.Freq", "Combination.Drug", "Subject.Race", "Treatment.Time_elapsed", "Subject", "Treatment.Duration"]}], "input": "It also highlights a current major etiologic question, that is, whether and to what degree lead exposure contributes to the development of hypertension, and raises the issue of whether lead-induced hypertension constitutes a subset of hypertension that is especially amenable to therapy with dietary calcium."}
{"potential therapeutic event": [], "adverse event": [{"trigger": "contributes ", "arguments": {"Subject.Gender": "NAN", "Treatment.Drug": "lead", "Subject.Population": "NAN", "Treatment": "lead exposure", "Subject.Disorder": "NAN", "Treatment.Disorder": "NAN", "Subject.Age": "NAN", "Treatment.Route": "exposure", "Treatment.Dosage": "NAN", "Effect": "hypertension", "Treatment.Freq": "NAN", "Combination.Drug": "NAN", "Subject.Race": "NAN", "Treatment.Time_elapsed": "NAN", "Subject": "NAN", "Treatment.Duration": "NAN"}}]}