{"instruction": "You are an expert in event argument extraction. Please extract event arguments and their roles from the input that conform to the schema definition, which already includes event trigger words. If an argument does not exist, return NAN or an empty dictionary. Please respond in the format of a JSON string.", "schema": [{"event_type": "adverse event", "arguments": ["Treatment.Dosage", "Subject.Age", "Treatment.Route", "Treatment.Duration", "Subject.Population", "Subject.Gender", "Subject", "Effect", "Treatment.Freq", "Treatment.Drug", "Combination.Drug", "Treatment.Time_elapsed", "Subject.Race", "Treatment.Disorder"]}], "input": "As atypical antipsychotics are increasingly used in the treatment of childhood behavioural disorders either as monotherapy or in combination with other medications, there is a need to know more about their safety, in particular during switching to and from methylphenidate treatment, as antipsychotics and methylphenidate have opposing effects on dopaminergic neurotransmission."}
{"adverse event": []}