{"instruction": "You are an expert in event argument extraction. Please extract event arguments and their roles from the input that conform to the schema definition, which already includes event trigger words. If an argument does not exist, return NAN or an empty dictionary. Please respond in the format of a JSON string.", "schema": [{"event_type": "adverse event", "arguments": ["Treatment.Route", "Subject", "Treatment.Duration", "Effect", "Subject.Disorder", "Combination.Drug", "Treatment.Freq", "Treatment", "Treatment.Time_elapsed", "Subject.Population", "Treatment.Disorder", "Subject.Age", "Subject.Race"]}], "input": "Symptomatic hypocalcaemia and renal impairment associated with bisphosphonate treatment in patients with multiple myeloma."}
{"adverse event": [{"Treatment.Route": "NAN", "Subject": "patients with multiple myeloma", "Treatment.Duration": "NAN", "Effect": "Symptomatic hypocalcaemia and renal impairment", "Subject.Disorder": "NAN", "Combination.Drug": "NAN", "Treatment.Freq": "NAN", "Treatment": "bisphosphonate treatment", "Treatment.Time_elapsed": "NAN", "Subject.Population": "NAN", "Treatment.Disorder": "multiple myeloma", "Subject.Age": "NAN", "Subject.Race": "NAN"}]}