{"instruction": "You are an expert in event extraction. Please extract events from the input that conform to the schema definition. Return an empty list for events that do not exist, and return NAN for arguments that do not exist. If an argument has multiple values, please return a list. Respond in the format of a JSON string.", "schema": [{"event_type": "adverse event", "trigger": true, "arguments": ["Subject.Age", "Subject.Race", "Subject.Population", "Treatment.Time_elapsed", "Subject", "Treatment.Route", "Treatment.Duration", "Subject.Disorder", "Subject.Gender", "Treatment.Freq", "Treatment", "Combination.Drug", "Treatment.Dosage", "Treatment.Disorder", "Effect", "Treatment.Drug"]}, {"event_type": "potential therapeutic event", "trigger": true, "arguments": ["Treatment.Drug", "Treatment.Time_elapsed", "Subject.Gender", "Subject.Population", "Subject.Race", "Treatment.Dosage", "Treatment", "Combination.Drug", "Subject", "Treatment.Freq", "Treatment.Duration", "Subject.Age", "Treatment.Disorder", "Effect", "Subject.Disorder"]}], "input": "However, continued low-dose MTX led, in spite of normal liver tests, 8 years after the last biopsy to liver failure and death in 1 of our patients."}
{"adverse event": [{"trigger": "led,", "arguments": {"Subject.Age": "NAN", "Subject.Race": "NAN", "Subject.Population": "NAN", "Treatment.Time_elapsed": "NAN", "Subject": "NAN", "Treatment.Route": "NAN", "Treatment.Duration": "NAN", "Subject.Disorder": "NAN", "Subject.Gender": "NAN", "Treatment.Freq": "NAN", "Treatment": "low-dose MTX", "Combination.Drug": "NAN", "Treatment.Dosage": "low-dose", "Treatment.Disorder": "NAN", "Effect": "liver failure and death", "Treatment.Drug": "MTX"}}], "potential therapeutic event": []}