{"instruction": "You are an expert in event argument extraction. Please extract event arguments and their roles from the input that conform to the schema definition, which already includes event trigger words. If an argument does not exist, return NAN or an empty dictionary. Please respond in the format of a JSON string.", "schema": [{"event_type": "adverse event", "arguments": ["Subject", "Treatment.Disorder", "Treatment.Freq", "Subject.Population", "Treatment.Time_elapsed", "Subject.Gender", "Subject.Age", "Treatment", "Combination.Drug", "Treatment.Duration", "Subject.Disorder", "Treatment.Dosage", "Treatment.Drug", "Effect", "Subject.Race", "Treatment.Route"]}], "input": "Despite aggressive medical management, including intravenous hydration and broad-spectrum antibiotics, the patient continued to become more confused, agitated, and despondent over the subsequent 24 hours."}
{"adverse event": []}