{"instruction": "You are an expert in event extraction. Please extract events from the input that conform to the schema definition. Return an empty list for events that do not exist, and return NAN for arguments that do not exist. If an argument has multiple values, please return a list. Respond in the format of a JSON string.", "schema": [{"event_type": "potential therapeutic event", "trigger": true, "arguments": ["Subject.Disorder", "Treatment.Drug", "Treatment.Freq", "Treatment.Time_elapsed", "Subject.Gender", "Effect", "Treatment", "Subject.Race", "Combination.Drug", "Treatment.Duration", "Treatment.Route", "Subject.Age", "Treatment.Dosage", "Subject.Population", "Subject", "Treatment.Disorder"]}, {"event_type": "adverse event", "trigger": true, "arguments": ["Subject", "Effect", "Subject.Disorder", "Treatment.Disorder", "Treatment.Freq", "Treatment.Duration", "Treatment.Drug", "Treatment.Time_elapsed", "Subject.Population", "Subject.Race", "Subject.Gender", "Treatment.Dosage", "Combination.Drug", "Treatment"]}], "input": "As atypical antipsychotics are increasingly used in the treatment of childhood behavioural disorders either as monotherapy or in combination with other medications, there is a need to know more about their safety, in particular during switching to and from methylphenidate treatment, as antipsychotics and methylphenidate have opposing effects on dopaminergic neurotransmission."}
{"potential therapeutic event": [{"trigger": "treatment ", "arguments": {"Subject.Disorder": "NAN", "Treatment.Drug": "atypical antipsychotics", "Treatment.Freq": "NAN", "Treatment.Time_elapsed": "NAN", "Subject.Gender": "NAN", "Effect": "NAN", "Treatment": ["atypical antipsychotics", "as monotherapy or in combination with other medications"], "Subject.Race": "NAN", "Combination.Drug": "NAN", "Treatment.Duration": "NAN", "Treatment.Route": "NAN", "Subject.Age": "NAN", "Treatment.Dosage": "NAN", "Subject.Population": "NAN", "Subject": "NAN", "Treatment.Disorder": "childhood behavioural disorders"}}], "adverse event": []}