{"instruction": "You are an expert in event extraction. Please extract events from the input that conform to the schema definition. Return an empty list for events that do not exist, and return NAN for arguments that do not exist. If an argument has multiple values, please return a list. Respond in the format of a JSON string.", "schema": [{"event_type": "adverse event", "trigger": true, "arguments": ["Treatment.Duration", "Treatment.Dosage", "Treatment.Route", "Effect", "Treatment", "Treatment.Time_elapsed", "Subject.Population", "Treatment.Disorder", "Treatment.Freq", "Combination.Drug", "Subject.Age", "Subject.Disorder", "Subject.Race", "Treatment.Drug", "Subject.Gender", "Subject"]}, {"event_type": "potential therapeutic event", "trigger": true, "arguments": ["Treatment.Duration", "Subject.Population", "Treatment.Time_elapsed", "Treatment.Dosage", "Effect", "Treatment", "Treatment.Disorder", "Combination.Drug", "Treatment.Route", "Subject.Age", "Subject", "Subject.Gender", "Treatment.Drug", "Subject.Disorder"]}], "input": "Simvastatin plasma concentration increased 30 times in this patient and statin induced muscle toxicity is related to the concentration of the statin in blood."}
{"adverse event": [{"trigger": "induced ", "arguments": {"Treatment.Duration": "NAN", "Treatment.Dosage": "NAN", "Treatment.Route": "NAN", "Effect": "muscle toxicity", "Treatment": "statin", "Treatment.Time_elapsed": "NAN", "Subject.Population": "NAN", "Treatment.Disorder": "NAN", "Treatment.Freq": "NAN", "Combination.Drug": "NAN", "Subject.Age": "NAN", "Subject.Disorder": "Simvastatin plasma concentration increased 30 times", "Subject.Race": "NAN", "Treatment.Drug": "statin", "Subject.Gender": "NAN", "Subject": "Simvastatin plasma concentration increased 30 times in this patient"}}], "potential therapeutic event": []}