{"instruction": "You are an expert in event extraction. Please extract events from the input that conform to the schema definition. Return an empty list for events that do not exist, and return NAN for arguments that do not exist. If an argument has multiple values, please return a list. Respond in the format of a JSON string.", "schema": [{"event_type": "potential therapeutic event", "trigger": true, "arguments": ["Treatment.Disorder", "Treatment.Dosage", "Treatment", "Treatment.Time_elapsed", "Treatment.Duration", "Combination.Drug", "Treatment.Freq", "Treatment.Drug", "Subject.Gender", "Treatment.Route", "Subject.Population", "Subject.Age", "Subject.Disorder", "Subject.Race", "Subject"]}, {"event_type": "adverse event", "trigger": true, "arguments": ["Subject.Population", "Treatment.Disorder", "Treatment.Duration", "Treatment.Drug", "Subject.Age", "Effect", "Combination.Drug", "Subject", "Treatment.Freq", "Treatment", "Subject.Gender", "Subject.Disorder", "Treatment.Dosage", "Treatment.Time_elapsed", "Subject.Race", "Treatment.Route"]}], "input": "This article reports the case of an otherwise healthy patient who experienced permanent sensorineural hearing loss after a brief course of naproxen and reviews the literature on NSAID-related permanent sensorineural hearing loss."}
{"potential therapeutic event": [], "adverse event": [{"trigger": "after ", "arguments": {"Subject.Population": "NAN", "Treatment.Disorder": "NAN", "Treatment.Duration": "brief course", "Treatment.Drug": "naproxen", "Subject.Age": "NAN", "Effect": "permanent sensorineural hearing loss", "Combination.Drug": "NAN", "Subject": "an otherwise healthy patient", "Treatment.Freq": "NAN", "Treatment": "a brief course of naproxen", "Subject.Gender": "NAN", "Subject.Disorder": "NAN", "Treatment.Dosage": "NAN", "Treatment.Time_elapsed": "NAN", "Subject.Race": "NAN", "Treatment.Route": "NAN"}}]}