{"instruction": "You are an expert in named entity recognition. Please extract entities that match the schema definition from the input. Return an empty list if the entity type does not exist. Please respond in the format of a JSON string.", "schema": ["GENE"], "input": "A method for the simultaneous determination of de ( N - methyl ) - N - ethyl - 8 , 9 - anhydroerythromycin A 6 , 9 - hemiacetal ( EM523 , I ) and its three metabolites in human plasma and urine has been developed using high - performance liquid chromatography ( HPLC ) with chemiluminescence ( CL ) detection ."}
{"GENE": []}