{"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "While doxorubicin was administered , the patient presented thoracic pain and breathing distress due to superior vena cava perforation by the central catheter and subsequent extravasation of the drug into the mediastinum ."}
{"adverse effect": [{"subject": "thoracic pain", "object": "doxorubicin"}, {"subject": "breathing distress", "object": "doxorubicin"}]}