{"instruction": "You are an expert in event extraction. Please extract events from the input that conform to the schema definition. Return an empty list for events that do not exist, and return NAN for arguments that do not exist. If an argument has multiple values, please return a list. Respond in the format of a JSON string.", "schema": [{"event_type": "potential therapeutic event", "trigger": true, "arguments": ["Treatment.Freq", "Combination.Drug", "Treatment.Disorder", "Subject.Gender", "Subject", "Effect", "Subject.Age", "Subject.Population", "Subject.Race", "Treatment.Dosage", "Treatment", "Treatment.Route", "Treatment.Duration"]}, {"event_type": "adverse event", "trigger": true, "arguments": ["Effect", "Treatment.Time_elapsed", "Treatment.Dosage", "Treatment.Duration", "Subject.Race", "Subject.Age", "Subject.Population", "Subject.Disorder", "Treatment.Route", "Subject.Gender", "Treatment", "Treatment.Drug", "Treatment.Disorder", "Treatment.Freq", "Subject", "Combination.Drug"]}], "input": "A case of toxic hepatitis caused by combination therapy with methotrexate and etretinate in the treatment of severe psoriasis is presented in a 47-year-old woman."}
{"potential therapeutic event": [], "adverse event": [{"trigger": "caused ", "arguments": {"Effect": "toxic hepatitis", "Treatment.Time_elapsed": "NAN", "Treatment.Dosage": "NAN", "Treatment.Duration": "NAN", "Subject.Race": "NAN", "Subject.Age": "47-year-old", "Subject.Population": "NAN", "Subject.Disorder": "NAN", "Treatment.Route": "NAN", "Subject.Gender": "woman", "Treatment": "combination therapy with methotrexate and etretinate", "Treatment.Drug": ["etretinate", "methotrexate"], "Treatment.Disorder": "severe psoriasis", "Treatment.Freq": "NAN", "Subject": ["psoriasis", "a 47-year-old woman"], "Combination.Drug": ["etretinate", "methotrexate"]}}]}