{"instruction": "You are an expert in event extraction. Please extract events from the input that conform to the schema definition. Return an empty list for events that do not exist, and return NAN for arguments that do not exist. If an argument has multiple values, please return a list. Respond in the format of a JSON string.", "schema": [{"event_type": "potential therapeutic event", "trigger": true, "arguments": ["Subject.Gender", "Subject.Race", "Subject.Population", "Subject.Disorder", "Treatment.Disorder", "Subject", "Treatment.Drug", "Effect", "Treatment", "Treatment.Duration", "Treatment.Freq", "Combination.Drug"]}, {"event_type": "adverse event", "trigger": true, "arguments": ["Treatment.Dosage", "Subject.Disorder", "Treatment.Freq", "Treatment.Duration", "Treatment", "Subject.Race", "Effect", "Treatment.Route", "Subject", "Subject.Population", "Subject.Gender", "Subject.Age", "Combination.Drug", "Treatment.Disorder", "Treatment.Drug", "Treatment.Time_elapsed"]}], "input": "With combined use, clinicians should be aware, when phenytoin is added, of the potential for reexacerbation of pulmonary symptomatology due to lowered serum theophylline concentrations."}
{"potential therapeutic event": [], "adverse event": [{"trigger": "due ", "arguments": {"Treatment.Dosage": "NAN", "Subject.Disorder": "NAN", "Treatment.Freq": "NAN", "Treatment.Duration": "NAN", "Treatment": ["theophylline", "phenytoin is added"], "Subject.Race": "NAN", "Effect": "reexacerbation of pulmonary symptomatology", "Treatment.Route": "NAN", "Subject": "NAN", "Subject.Population": "NAN", "Subject.Gender": "NAN", "Subject.Age": "NAN", "Combination.Drug": ["theophylline", "phenytoin"], "Treatment.Disorder": "NAN", "Treatment.Drug": ["theophylline", "phenytoin"], "Treatment.Time_elapsed": "NAN"}}]}