{"instruction": "You are an expert in event argument extraction. Please extract event arguments and their roles from the input that conform to the schema definition, which already includes event trigger words. If an argument does not exist, return NAN or an empty dictionary. Please respond in the format of a JSON string.", "schema": [{"event_type": "adverse event", "arguments": ["Treatment.Drug", "Subject.Age", "Treatment.Time_elapsed", "Treatment.Freq", "Subject.Population", "Subject.Gender", "Treatment.Route", "Subject.Disorder", "Combination.Drug", "Treatment.Duration", "Treatment.Disorder"]}], "input": "The use of telithromycin in patients receiving multiple doses of oxycodone for pain relief may increase the risk of opioid adverse effects."}
{"adverse event": [{"Treatment.Drug": "telithromycin", "Subject.Age": "NAN", "Treatment.Time_elapsed": "NAN", "Treatment.Freq": "NAN", "Subject.Population": "NAN", "Subject.Gender": "NAN", "Treatment.Route": "NAN", "Subject.Disorder": "NAN", "Combination.Drug": "NAN", "Treatment.Duration": "NAN", "Treatment.Disorder": "NAN"}]}