{"instruction": "You are an expert in named entity recognition. Please extract entities that match the schema definition from the input. Return an empty list if the entity type does not exist. Please respond in the format of a JSON string.", "schema": ["Chemical"], "input": "Based on an orthogonal experimental design L9 ( 3 ( 3 ) ) , polynomial regression models were developed to evaluate correlation between microparticle properties ( encapsulation efficiency and drug release ) and variables ( X1 : weight ratio of polymer to drug , X2 : volume ratio of oil to water and X3 : Q - flow of spray dryer ) ."}
{"Chemical": []}