{"instruction": "You are an expert in named entity recognition. Please extract entities that match the schema definition from the input. Return an empty list if the entity type does not exist. Please respond in the format of a JSON string.", "schema": ["cell type", "DNA", "RNA", "cell line", "protein"], "input": "These studies have been extended to show that (i) a mutant EBV strain lacking the gene encoding EBNA 2 fails to switch from Wp to Cp usage in primary B lymphocytes , although the virus contains a functional Cp ; (ii) a region from -429 to -245 base pairs upstream of Cp is essential for Cp activity in B lymphocytes , but only in the context of upstream and downstream sequences ; (iii) this region contains an EBNA 2 -dependent enhancer ; and (iv) DNase I protection employing nuclear extracts from B and T lymphocytes revealed a B-cell-specific footprint in the region of the EBNA 2 -dependent enhancer ."}
{"cell type": ["primary B lymphocytes", "B lymphocytes"], "DNA": ["Wp", "Cp", "-429 to -245 base pairs", "upstream", "upstream and downstream sequences", "downstream sequences", "EBNA 2 -dependent enhancer", "B-cell-specific footprint"], "RNA": [], "cell line": [], "protein": ["EBNA 2", "DNase I"]}