{"instruction": "You are an expert in event argument extraction. Please extract event arguments and their roles from the input that conform to the schema definition, which already includes event trigger words. If an argument does not exist, return NAN or an empty dictionary. Please respond in the format of a JSON string.", "schema": [{"event_type": "adverse event", "arguments": ["Treatment", "Treatment.Route", "Treatment.Dosage", "Subject.Disorder", "Treatment.Time_elapsed", "Combination.Drug", "Subject.Race", "Subject.Gender", "Subject", "Treatment.Freq", "Treatment.Disorder", "Subject.Age", "Treatment.Drug", "Subject.Population"]}], "input": "Nail and skin alterations associated with the use of chemotherapy have been described in the last decade involving various combinations of two different types of nail changes."}
{"adverse event": [{"Treatment": "chemotherapy", "Treatment.Route": "chemotherapy", "Treatment.Dosage": "NAN", "Subject.Disorder": "NAN", "Treatment.Time_elapsed": "NAN", "Combination.Drug": "NAN", "Subject.Race": "NAN", "Subject.Gender": "NAN", "Subject": "NAN", "Treatment.Freq": "NAN", "Treatment.Disorder": "NAN", "Subject.Age": "NAN", "Treatment.Drug": "NAN", "Subject.Population": "NAN"}]}