{"instruction": "You are an expert in event extraction. Please extract events from the input that conform to the schema definition. Return an empty list for events that do not exist, and return NAN for arguments that do not exist. If an argument has multiple values, please return a list. Respond in the format of a JSON string.", "schema": [{"event_type": "adverse event", "trigger": true, "arguments": ["Treatment", "Treatment.Time_elapsed", "Treatment.Duration", "Treatment.Drug", "Treatment.Disorder", "Treatment.Freq", "Treatment.Route", "Subject.Gender", "Effect", "Subject.Population", "Combination.Drug", "Subject.Disorder", "Subject", "Subject.Age"]}, {"event_type": "potential therapeutic event", "trigger": true, "arguments": ["Treatment.Drug", "Treatment.Route", "Subject.Population", "Combination.Drug", "Subject.Race", "Treatment.Disorder", "Subject.Age", "Effect", "Treatment", "Treatment.Dosage", "Subject.Disorder", "Subject", "Treatment.Duration"]}], "input": "These findings suggest that the corneal and retinal changes are the result of a toxic effect of tamoxifen when used in the doses and duration described."}
{"adverse event": [{"trigger": "result ", "arguments": {"Treatment": "tamoxifen", "Treatment.Time_elapsed": "NAN", "Treatment.Duration": "NAN", "Treatment.Drug": "tamoxifen", "Treatment.Disorder": "NAN", "Treatment.Freq": "NAN", "Treatment.Route": "NAN", "Subject.Gender": "NAN", "Effect": "corneal and retinal changes", "Subject.Population": "NAN", "Combination.Drug": "NAN", "Subject.Disorder": "NAN", "Subject": "NAN", "Subject.Age": "NAN"}}], "potential therapeutic event": []}