{"instruction": "You are an expert in event extraction. Please extract events from the input that conform to the schema definition. Return an empty list for events that do not exist, and return NAN for arguments that do not exist. If an argument has multiple values, please return a list. Respond in the format of a JSON string.", "schema": [{"event_type": "adverse event", "trigger": true, "arguments": ["Treatment.Duration", "Treatment.Drug", "Subject.Gender", "Subject.Population", "Treatment.Disorder", "Treatment.Freq", "Treatment.Time_elapsed", "Combination.Drug", "Treatment.Dosage", "Treatment.Route", "Subject.Age", "Subject.Disorder", "Effect", "Subject", "Treatment"]}, {"event_type": "potential therapeutic event", "trigger": true, "arguments": ["Treatment.Route", "Subject", "Subject.Population", "Treatment.Disorder", "Subject.Age", "Treatment.Drug", "Treatment.Time_elapsed", "Treatment.Freq", "Subject.Race", "Subject.Gender", "Subject.Disorder", "Treatment.Duration", "Treatment.Dosage", "Combination.Drug", "Effect", "Treatment"]}], "input": "To report the results of therapeutic drug monitoring of lopinavir/ritonavir and itraconazole concentrations in an HIV-infected male who was treated for histoplasmosis."}
{"adverse event": [], "potential therapeutic event": [{"trigger": "treated ", "arguments": {"Treatment.Route": "NAN", "Subject": "an HIV-infected male", "Subject.Population": "NAN", "Treatment.Disorder": ["HIV", "histoplasmosis"], "Subject.Age": "NAN", "Treatment.Drug": ["lopinavir", "itraconazole", "ritonavir"], "Treatment.Time_elapsed": "NAN", "Treatment.Freq": "NAN", "Subject.Race": "NAN", "Subject.Gender": "male", "Subject.Disorder": "NAN", "Treatment.Duration": "NAN", "Treatment.Dosage": "NAN", "Combination.Drug": ["lopinavir", "itraconazole", "ritonavir"], "Effect": "NAN", "Treatment": "lopinavir/ritonavir and itraconazole concentrations"}}]}