{"instruction": "You are an expert in event extraction. Please extract events from the input that conform to the schema definition. Return an empty list for events that do not exist, and return NAN for arguments that do not exist. If an argument has multiple values, please return a list. Respond in the format of a JSON string.", "schema": [{"event_type": "potential therapeutic event", "trigger": true, "arguments": ["Treatment.Drug", "Treatment.Route", "Effect", "Treatment.Disorder", "Subject.Disorder", "Treatment.Time_elapsed", "Subject.Race", "Treatment.Dosage"]}, {"event_type": "adverse event", "trigger": true, "arguments": ["Treatment.Dosage", "Subject.Age", "Treatment.Drug", "Treatment.Freq", "Treatment.Duration", "Subject.Gender", "Treatment", "Combination.Drug", "Treatment.Time_elapsed", "Subject.Race", "Effect", "Subject.Disorder", "Treatment.Route", "Subject.Population"]}], "input": "Nail and skin alterations associated with the use of chemotherapy have been described in the last decade involving various combinations of two different types of nail changes."}
{"potential therapeutic event": [], "adverse event": [{"trigger": "associated ", "arguments": {"Treatment.Dosage": "NAN", "Subject.Age": "NAN", "Treatment.Drug": "NAN", "Treatment.Freq": "NAN", "Treatment.Duration": "NAN", "Subject.Gender": "NAN", "Treatment": "chemotherapy", "Combination.Drug": "NAN", "Treatment.Time_elapsed": "NAN", "Subject.Race": "NAN", "Effect": "Nail and skin alterations", "Subject.Disorder": "NAN", "Treatment.Route": "chemotherapy", "Subject.Population": "NAN"}}]}