{"instruction": "You are an expert in event argument extraction. Please extract event arguments and their roles from the input that conform to the schema definition, which already includes event trigger words. If an argument does not exist, return NAN or an empty dictionary. Please respond in the format of a JSON string.", "schema": [{"event_type": "adverse event", "arguments": ["Treatment.Time_elapsed", "Treatment.Duration", "Subject.Disorder", "Subject.Gender", "Treatment.Dosage", "Treatment.Disorder", "Subject.Age", "Treatment.Drug", "Subject", "Subject.Population", "Treatment.Route", "Effect", "Combination.Drug", "Treatment", "Treatment.Freq"]}], "input": "Abiraterone acetate, an androgen biosynthesis inhibitor, prolongs survival in men with metastatic castration-resistant prostate cancer (mCRPC) in the pre- and post-chemotherapy setting as demonstrated by the pivotal phase III studies COU-AA-301 and COU-AA-302."}
{"adverse event": []}