{"instruction": "You are an expert in event argument extraction. Please extract event arguments and their roles from the input that conform to the schema definition, which already includes event trigger words. If an argument does not exist, return NAN or an empty dictionary. Please respond in the format of a JSON string.", "schema": [{"event_type": "adverse event", "arguments": ["Subject.Age", "Treatment.Duration", "Subject.Race", "Treatment.Freq", "Subject", "Treatment.Dosage", "Treatment.Time_elapsed", "Subject.Population", "Subject.Disorder", "Treatment", "Effect", "Treatment.Drug", "Treatment.Disorder", "Treatment.Route"]}], "input": "Two cases are described of chronic schizophrenic patients maintained on depot neuroleptics, who developed severe extrapyramidal symptoms following a period of heavy betel nut consumption."}
{"adverse event": [{"Subject.Age": "NAN", "Treatment.Duration": "NAN", "Subject.Race": "NAN", "Treatment.Freq": "NAN", "Subject": "Two cases", "Treatment.Dosage": "NAN", "Treatment.Time_elapsed": "NAN", "Subject.Population": "Two", "Subject.Disorder": "NAN", "Treatment": ["heavy betel nut consumption", "depot neuroleptics"], "Effect": "severe extrapyramidal symptoms", "Treatment.Drug": ["depot neuroleptics", "betel nut"], "Treatment.Disorder": "chronic schizophrenic", "Treatment.Route": "NAN"}]}