{"instruction": "You are an expert in named entity recognition. Please extract entities that match the schema definition from the input. Return an empty list if the entity type does not exist. Please respond in the format of a JSON string.", "schema": ["cell line", "RNA", "cell type", "protein", "DNA"], "input": "The minimal region of the human tumor necrosis factor alpha ( TNF-alpha ) gene promoter necessary for its transcriptional induction by phorbol esters ( PMA ) in human T and B lymphocyte cell lines has been localized between -52 and +89 nucleotides (nt) relative to the gene's transcriptional start site ."}
{"cell line": ["human T", "human T and B lymphocyte cell lines", "B lymphocyte cell lines"], "RNA": [], "cell type": [], "protein": ["human tumor necrosis factor alpha", "TNF-alpha"], "DNA": ["human tumor necrosis factor alpha ( TNF-alpha ) gene promoter", "-52 and +89 nucleotides", "transcriptional start site"]}