{"instruction": "You are an expert in event argument extraction. Please extract event arguments and their roles from the input that conform to the schema definition, which already includes event trigger words. If an argument does not exist, return NAN or an empty dictionary. Please respond in the format of a JSON string.", "schema": [{"event_type": "adverse event", "arguments": ["Treatment", "Treatment.Dosage", "Subject.Disorder", "Treatment.Freq", "Subject.Race", "Effect", "Treatment.Time_elapsed", "Subject.Age", "Treatment.Drug", "Treatment.Route", "Subject.Gender", "Subject.Population", "Treatment.Duration", "Subject"]}], "input": "CONCLUSIONS: This case report showed that the clinical appearance of Hashimoto's disease after IFN-alpha therapy for chronic C hepatitis in our patient was associated with a specific genetic predisposition (DR5) for this pathology."}
{"adverse event": [{"Treatment": "IFN-alpha", "Treatment.Dosage": "NAN", "Subject.Disorder": "a specific genetic predisposition (DR5) for this pathology", "Treatment.Freq": "NAN", "Subject.Race": "NAN", "Effect": "clinical appearance of Hashimoto's disease", "Treatment.Time_elapsed": "NAN", "Subject.Age": "NAN", "Treatment.Drug": "IFN-alpha", "Treatment.Route": "NAN", "Subject.Gender": "NAN", "Subject.Population": "NAN", "Treatment.Duration": "NAN", "Subject": "our patient"}]}