{"instruction": "You are an expert in named entity recognition. Please extract entities that match the schema definition from the input. Return an empty list if the entity type does not exist. Please respond in the format of a JSON string.", "schema": ["Chemical"], "input": "Using cultured human keratinocytes and diabetic rat model , the current study showed that high - glucose environment enhanced IL - 8 production via epidermal growth factor receptor ( EGFR ) - extracelluar signal - regulated kinase ( ERK ) pathway in a reactive oxygen species ( ROS ) - dependent manner in keratinocytes ."}
{"Chemical": ["glucose", "oxygen"]}