{"instruction": "You are an expert in event extraction. Please extract events from the input that conform to the schema definition. Return an empty list for events that do not exist, and return NAN for arguments that do not exist. If an argument has multiple values, please return a list. Respond in the format of a JSON string.", "schema": [{"event_type": "potential therapeutic event", "trigger": true, "arguments": ["Combination.Drug", "Subject.Population", "Treatment.Freq", "Subject.Disorder", "Subject.Age", "Treatment.Duration", "Effect", "Subject.Gender", "Subject", "Treatment.Disorder", "Treatment.Time_elapsed", "Treatment", "Treatment.Drug", "Subject.Race"]}, {"event_type": "adverse event", "trigger": true, "arguments": ["Subject.Age", "Treatment.Duration", "Treatment.Freq", "Treatment.Dosage", "Treatment.Disorder", "Subject.Race", "Treatment", "Combination.Drug", "Subject.Gender", "Treatment.Drug", "Subject.Population", "Subject.Disorder", "Treatment.Route", "Effect", "Subject", "Treatment.Time_elapsed"]}], "input": "When SASP was changed to 5-aminosalicylic acid (5-ASA), his skin eruptions were resolved, however, he developed weakness and atrophy in his right arm as well as progressive worsening of the dysesthesia in his legs and gait disturbance."}
{"potential therapeutic event": [], "adverse event": [{"trigger": "developed ", "arguments": {"Subject.Age": "NAN", "Treatment.Duration": "NAN", "Treatment.Freq": "NAN", "Treatment.Dosage": "NAN", "Treatment.Disorder": "NAN", "Subject.Race": "NAN", "Treatment": "SASP was changed to 5-aminosalicylic acid (5-ASA)", "Combination.Drug": "NAN", "Subject.Gender": "NAN", "Treatment.Drug": ["SASP", "5-aminosalicylic acid"], "Subject.Population": "NAN", "Subject.Disorder": "NAN", "Treatment.Route": "NAN", "Effect": "weakness and atrophy in his right arm as well as progressive worsening of the dysesthesia in his legs and gait disturbance.", "Subject": "he", "Treatment.Time_elapsed": "NAN"}}]}