{"instruction": "You are an expert in event argument extraction. Please extract event arguments and their roles from the input that conform to the schema definition, which already includes event trigger words. If an argument does not exist, return NAN or an empty dictionary. Please respond in the format of a JSON string.", "schema": [{"event_type": "potential therapeutic event", "arguments": ["Subject.Population", "Treatment.Duration", "Subject.Age", "Combination.Drug", "Subject", "Effect", "Treatment.Freq", "Treatment.Time_elapsed", "Treatment.Dosage", "Subject.Gender", "Treatment.Drug", "Subject.Disorder", "Treatment.Disorder", "Treatment.Route", "Treatment"]}], "input": "The patient was placed on omeprazole after his first cycle of high-dose methotrexate for stress ulcer prophylaxis, and it was discontinued before the start of the first day of the patient's second round of high-dose methotrexate."}
{"potential therapeutic event": [{"Subject.Population": "NAN", "Treatment.Duration": "NAN", "Subject.Age": "NAN", "Combination.Drug": "NAN", "Subject": "The patient", "Effect": "NAN", "Treatment.Freq": "NAN", "Treatment.Time_elapsed": "NAN", "Treatment.Dosage": "high-dose", "Subject.Gender": "NAN", "Treatment.Drug": ["omeprazole", "methotrexate"], "Subject.Disorder": "NAN", "Treatment.Disorder": "stress ulcer", "Treatment.Route": "NAN", "Treatment": "methotrexate"}]}