{"instruction": "You are an expert in event argument extraction. Please extract event arguments and their roles from the input that conform to the schema definition, which already includes event trigger words. If an argument does not exist, return NAN or an empty dictionary. Please respond in the format of a JSON string.", "schema": [{"event_type": "adverse event", "arguments": ["Treatment.Duration", "Treatment.Drug", "Treatment", "Treatment.Route", "Combination.Drug", "Subject.Population", "Effect", "Subject.Gender", "Subject", "Treatment.Dosage", "Subject.Age", "Treatment.Disorder", "Subject.Race", "Treatment.Freq", "Subject.Disorder", "Treatment.Time_elapsed"]}], "input": "Subtherapeutic warfarin is not associated with increased hemorrhage rates in ischemic strokes treated with tissue plasminogen activator."}
{"adverse event": [{"Treatment.Duration": "NAN", "Treatment.Drug": ["warfarin", "tissue plasminogen activator"], "Treatment": ["Subtherapeutic warfarin", "treated with tissue plasminogen activator"], "Treatment.Route": "NAN", "Combination.Drug": ["warfarin", "tissue plasminogen activator"], "Subject.Population": "NAN", "Effect": "increased hemorrhage rates", "Subject.Gender": "NAN", "Subject": "NAN", "Treatment.Dosage": "NAN", "Subject.Age": "NAN", "Treatment.Disorder": "ischemic strokes", "Subject.Race": "NAN", "Treatment.Freq": "NAN", "Subject.Disorder": "NAN", "Treatment.Time_elapsed": "NAN"}]}