{"instruction": "You are an expert in event argument extraction. Please extract event arguments and their roles from the input that conform to the schema definition, which already includes event trigger words. If an argument does not exist, return NAN or an empty dictionary. Please respond in the format of a JSON string.", "schema": [{"event_type": "adverse event", "arguments": ["Treatment.Time_elapsed", "Subject.Age", "Treatment.Duration", "Subject.Disorder", "Subject.Race", "Treatment.Drug", "Subject.Population", "Combination.Drug", "Effect", "Treatment.Dosage", "Treatment.Disorder", "Treatment", "Treatment.Route", "Subject", "Treatment.Freq"]}], "input": "The NZ Pharmacovigilance Centre has received 7 additional reports of severe infections in patients with RA taking leflunomide."}
{"adverse event": [{"Treatment.Time_elapsed": "NAN", "Subject.Age": "NAN", "Treatment.Duration": "NAN", "Subject.Disorder": "NAN", "Subject.Race": "NAN", "Treatment.Drug": "leflunomide", "Subject.Population": "NAN", "Combination.Drug": "NAN", "Effect": "severe infections", "Treatment.Dosage": "NAN", "Treatment.Disorder": "RA", "Treatment": "leflunomide", "Treatment.Route": "NAN", "Subject": "patients with RA", "Treatment.Freq": "NAN"}]}