{"instruction": "You are an expert in event extraction. Please extract events from the input that conform to the schema definition. Return an empty list for events that do not exist, and return NAN for arguments that do not exist. If an argument has multiple values, please return a list. Respond in the format of a JSON string.", "schema": [{"event_type": "potential therapeutic event", "trigger": true, "arguments": ["Treatment.Drug", "Subject", "Subject.Age", "Treatment.Disorder", "Treatment.Dosage", "Treatment.Duration", "Treatment.Route", "Subject.Gender", "Combination.Drug", "Subject.Population", "Treatment.Time_elapsed", "Subject.Race", "Treatment.Freq", "Treatment", "Subject.Disorder", "Effect"]}, {"event_type": "adverse event", "trigger": true, "arguments": ["Treatment.Time_elapsed", "Effect", "Subject.Disorder", "Treatment.Freq", "Subject.Race", "Subject.Gender", "Treatment.Dosage", "Subject.Population", "Subject", "Treatment.Disorder", "Combination.Drug", "Treatment.Duration", "Treatment.Route", "Treatment.Drug", "Treatment", "Subject.Age"]}], "input": "The tirapazamine-plus-cisplatin regimen was associated with mild to moderate adverse events, including acute, reversible hearing loss, reversible, intermittent muscle cramping, diarrhea, skin rash, nausea, and vomiting."}
{"potential therapeutic event": [], "adverse event": [{"trigger": "associated ", "arguments": {"Treatment.Time_elapsed": "NAN", "Effect": "mild to moderate adverse events, including acute, reversible hearing loss, reversible, intermittent muscle cramping, diarrhea, skin rash, nausea, and vomiting", "Subject.Disorder": "NAN", "Treatment.Freq": "NAN", "Subject.Race": "NAN", "Subject.Gender": "NAN", "Treatment.Dosage": "NAN", "Subject.Population": "NAN", "Subject": "NAN", "Treatment.Disorder": "NAN", "Combination.Drug": ["tirapazamine", "cisplatin"], "Treatment.Duration": "NAN", "Treatment.Route": "NAN", "Treatment.Drug": ["tirapazamine", "cisplatin"], "Treatment": "tirapazamine-plus-cisplatin regimen", "Subject.Age": "NAN"}}]}