{"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "These cases and a review of the literature suggested that hepatotoxicity , though rare , should be added to the list of adverse reactions to D - penicillamine ."}
{"adverse effect": [{"subject": "hepatotoxicity", "object": "D - penicillamine"}]}