{"instruction": "You are an expert in event argument extraction. Please extract event arguments and their roles from the input that conform to the schema definition, which already includes event trigger words. If an argument does not exist, return NAN or an empty dictionary. Please respond in the format of a JSON string.", "schema": [{"event_type": "adverse event", "arguments": ["Subject.Race", "Effect", "Treatment.Time_elapsed", "Treatment.Drug", "Treatment.Disorder", "Treatment.Dosage", "Subject.Age", "Combination.Drug", "Treatment.Route", "Treatment", "Subject.Disorder", "Treatment.Freq", "Treatment.Duration", "Subject.Gender", "Subject", "Subject.Population"]}], "input": "Does the use of insulin in a patient with liver dysfunction increase water retention in the body, i.e. cause insulin oedema?"}
{"adverse event": [{"Subject.Race": "NAN", "Effect": "increase water retention in the body, i.e. cause insulin oedema?", "Treatment.Time_elapsed": "NAN", "Treatment.Drug": "insulin", "Treatment.Disorder": "liver dysfunction", "Treatment.Dosage": "NAN", "Subject.Age": "NAN", "Combination.Drug": "NAN", "Treatment.Route": "NAN", "Treatment": "insulin", "Subject.Disorder": "NAN", "Treatment.Freq": "NAN", "Treatment.Duration": "NAN", "Subject.Gender": "NAN", "Subject": "a patient with liver dysfunction", "Subject.Population": "NAN"}]}