{"instruction": "You are an expert in named entity recognition. Please extract entities that match the schema definition from the input. Return an empty list if the entity type does not exist. Please respond in the format of a JSON string.", "schema": ["Disease"], "input": "Similarly , while the cumulative data revealed a predominance of missense mutations among the WASP gene lesions observed in boys with isolated thrombocytopenia , missense mutations were not exclusively associated with milder WAS phenotypes , but also comprised a substantial portion ( 38 % ) of the WASP gene defects found in patients with severe disease ."}
{"Disease": ["WAS", "isolated thrombocytopenia"]}