{"instruction": "You are an expert in event extraction. Please extract events from the input that conform to the schema definition. Return an empty list for events that do not exist, and return NAN for arguments that do not exist. If an argument has multiple values, please return a list. Respond in the format of a JSON string.", "schema": [{"event_type": "potential therapeutic event", "trigger": true, "arguments": ["Treatment.Freq", "Effect", "Treatment", "Combination.Drug", "Subject.Race", "Subject.Disorder", "Treatment.Duration", "Treatment.Disorder", "Treatment.Time_elapsed", "Subject.Population", "Subject.Age", "Treatment.Drug", "Subject.Gender", "Treatment.Route"]}, {"event_type": "adverse event", "trigger": true, "arguments": ["Subject.Gender", "Treatment.Route", "Treatment.Drug", "Treatment", "Treatment.Duration", "Treatment.Dosage", "Subject.Population", "Combination.Drug", "Subject.Disorder", "Subject.Age", "Subject.Race", "Effect", "Treatment.Freq", "Treatment.Disorder", "Treatment.Time_elapsed"]}], "input": "We conclude that while thrombocytopenia and schistocytosis can be seen in quinine-associated TTP/HUS, the pathophysiology seems to be distinct from that seen in most cases of idiopathic TTP (i.e., severely decreased ADAMTS13 with an inhibitor)."}
{"potential therapeutic event": [], "adverse event": [{"trigger": "associated ", "arguments": {"Subject.Gender": "NAN", "Treatment.Route": "NAN", "Treatment.Drug": "quinine", "Treatment": "quinine", "Treatment.Duration": "NAN", "Treatment.Dosage": "NAN", "Subject.Population": "NAN", "Combination.Drug": "NAN", "Subject.Disorder": "NAN", "Subject.Age": "NAN", "Subject.Race": "NAN", "Effect": ["TTP/HUS", "thrombocytopenia and schistocytosis"], "Treatment.Freq": "NAN", "Treatment.Disorder": "NAN", "Treatment.Time_elapsed": "NAN"}}]}