{"instruction": "You are an expert in named entity recognition. Please extract entities that match the schema definition from the input. Return an empty list if the entity type does not exist. Please respond in the format of a JSON string.", "schema": ["DNA", "cell type", "RNA", "cell line", "protein"], "input": "Small apolar substitutions ( 11 alpha-methyl, 11 alpha-fluoromethyl ) did not markedly decrease the affinity for the vitamin D receptor , but larger ( 11 alpha-chloromethyl or 11 alpha- or 11 beta-phenyl ) or more polar substitutions ( 11 alpha-hydroxymethyl, 11 alpha-(2-hydroxyethyl ] decreased the affinity to less than 5% of that of 1 alpha,25-OH)2D3 ."}
{"DNA": [], "cell type": [], "RNA": [], "cell line": [], "protein": ["vitamin D receptor"]}