{"instruction": "You are an expert in event argument extraction. Please extract event arguments and their roles from the input that conform to the schema definition, which already includes event trigger words. If an argument does not exist, return NAN or an empty dictionary. Please respond in the format of a JSON string.", "schema": [{"event_type": "adverse event", "arguments": ["Treatment.Duration", "Subject.Race", "Treatment.Time_elapsed", "Subject.Disorder", "Treatment", "Treatment.Drug", "Treatment.Route", "Subject", "Subject.Age", "Treatment.Disorder", "Effect", "Treatment.Dosage", "Subject.Population", "Combination.Drug", "Treatment.Freq"]}], "input": "Critically elevated INR in a patient on warfarin after increase in extended-release niacin dose."}
{"adverse event": [{"Treatment.Duration": "NAN", "Subject.Race": "NAN", "Treatment.Time_elapsed": "NAN", "Subject.Disorder": "NAN", "Treatment": ["increase in extended-release niacin dose", "warfarin"], "Treatment.Drug": ["warfarin", "niacin"], "Treatment.Route": "NAN", "Subject": "a patient", "Subject.Age": "NAN", "Treatment.Disorder": "NAN", "Effect": "elevated INR", "Treatment.Dosage": ["increase in", "dose"], "Subject.Population": "NAN", "Combination.Drug": "NAN", "Treatment.Freq": "NAN"}]}