{"instruction": "You are an expert in event extraction. Please extract events from the input that conform to the schema definition. Return an empty list for events that do not exist, and return NAN for arguments that do not exist. If an argument has multiple values, please return a list. Respond in the format of a JSON string.", "schema": [{"event_type": "adverse event", "trigger": true, "arguments": ["Subject", "Treatment.Time_elapsed", "Subject.Race", "Subject.Age", "Subject.Gender", "Treatment.Dosage", "Treatment.Duration", "Combination.Drug", "Treatment.Drug", "Treatment.Disorder", "Treatment.Freq", "Treatment.Route", "Subject.Disorder", "Subject.Population", "Effect", "Treatment"]}, {"event_type": "potential therapeutic event", "trigger": true, "arguments": ["Subject.Disorder", "Effect", "Treatment.Duration", "Subject.Gender", "Combination.Drug", "Subject.Age", "Treatment", "Treatment.Route", "Treatment.Disorder", "Treatment.Time_elapsed"]}], "input": "Peculiar nail-changes in a 70-year-old woman with rheumatoid arthritis occurring after approximately 1 year of penicillamine treatment are described."}
{"adverse event": [{"trigger": "after ", "arguments": {"Subject": "a 70-year-old woman with rheumatoid arthritis", "Treatment.Time_elapsed": "1 year", "Subject.Race": "NAN", "Subject.Age": "70-year-old", "Subject.Gender": "woman", "Treatment.Dosage": "NAN", "Treatment.Duration": "NAN", "Combination.Drug": "NAN", "Treatment.Drug": "penicillamine", "Treatment.Disorder": "rheumatoid arthritis", "Treatment.Freq": "NAN", "Treatment.Route": "NAN", "Subject.Disorder": "NAN", "Subject.Population": "NAN", "Effect": "Peculiar nail-changes", "Treatment": "penicillamine"}}], "potential therapeutic event": []}