{"instruction": "You are an expert in event argument extraction. Please extract event arguments and their roles from the input that conform to the schema definition, which already includes event trigger words. If an argument does not exist, return NAN or an empty dictionary. Please respond in the format of a JSON string.", "schema": [{"event_type": "adverse event", "arguments": ["Treatment.Route", "Combination.Drug", "Treatment.Freq", "Treatment.Duration", "Subject", "Subject.Gender", "Treatment.Dosage", "Subject.Population", "Treatment.Time_elapsed", "Treatment.Disorder", "Effect", "Subject.Race", "Subject.Disorder", "Subject.Age"]}], "input": "CONCLUSION: This report describes a case of a probable interaction between topical econazole lotion 1% and acenocoumarol that resulted in overanticoagulation and a life-threatening laryngeal hematoma in this elderly patient."}
{"adverse event": [{"Treatment.Route": ["lotion", "topical"], "Combination.Drug": ["econazole", "acenocoumarol"], "Treatment.Freq": "NAN", "Treatment.Duration": "NAN", "Subject": "elderly patient", "Subject.Gender": "NAN", "Treatment.Dosage": "NAN", "Subject.Population": "NAN", "Treatment.Time_elapsed": "NAN", "Treatment.Disorder": "NAN", "Effect": "overanticoagulation and a life-threatening laryngeal hematoma", "Subject.Race": "NAN", "Subject.Disorder": "NAN", "Subject.Age": "elderly"}]}