{"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "We further used immunohistochemistry ( IHC ) to examine the relative role of platelet - derived growth factor - B ( PDGF - B ) , insulin - like growth factor I ( IGF - I ) , transforming growth factor - beta1 ( TGF - beta1 ) and cyclooxygenase-2 ( COX-2 ) in the pathogenesis of BCNU - related pulmonary fibrosis ."}
{"adverse effect": [{"subject": "pulmonary fibrosis", "object": "BCNU"}]}