{"instruction": "You are an expert in event argument extraction. Please extract event arguments and their roles from the input that conform to the schema definition, which already includes event trigger words. If an argument does not exist, return NAN or an empty dictionary. Please respond in the format of a JSON string.", "schema": [{"event_type": "adverse event", "arguments": ["Treatment.Freq", "Treatment", "Subject", "Treatment.Dosage", "Subject.Disorder", "Treatment.Drug", "Subject.Age", "Subject.Gender", "Effect", "Subject.Population", "Treatment.Time_elapsed", "Subject.Race"]}], "input": "While the introduction of carmustine wafers (Gliadel wafers) into the tumor resection cavity has been shown to be a beneficial therapy for malignant glioma, it is recognized that clinically significant cerebral edema is a potential adverse effect."}
{"adverse event": [{"Treatment.Freq": "NAN", "Treatment": "the introduction of carmustine wafers (Gliadel wafers) into the tumor resection cavity", "Subject": "NAN", "Treatment.Dosage": "NAN", "Subject.Disorder": "NAN", "Treatment.Drug": "carmustine wafers", "Subject.Age": "NAN", "Subject.Gender": "NAN", "Effect": "significant cerebral edema", "Subject.Population": "NAN", "Treatment.Time_elapsed": "NAN", "Subject.Race": "NAN"}]}