{"instruction": "You are an expert in event argument extraction. Please extract event arguments and their roles from the input that conform to the schema definition, which already includes event trigger words. If an argument does not exist, return NAN or an empty dictionary. Please respond in the format of a JSON string.", "schema": [{"event_type": "adverse event", "arguments": ["Treatment", "Treatment.Disorder", "Subject", "Effect", "Subject.Age", "Treatment.Freq", "Subject.Race", "Subject.Disorder", "Treatment.Time_elapsed", "Treatment.Dosage", "Subject.Population", "Subject.Gender", "Combination.Drug", "Treatment.Duration", "Treatment.Drug"]}], "input": "We report 5 patients (3 patients with chronic hepatitis C treated with pegylated interferon alfa-2b in association with oral ribavirin and two patients with chronic myelocytic leukemia) who developed local cutaneous reactions at sites of injection after the administration of weekly subcutaneous injections of pegylated interferon alfa-2b at different doses."}
{"adverse event": [{"Treatment": "administration of weekly subcutaneous injections of pegylated interferon alfa-2b at different doses", "Treatment.Disorder": "chronic myelocytic leukemia", "Subject": "two patients with chronic myelocytic leukemia", "Effect": "local cutaneous reactions at sites of injection", "Subject.Age": "NAN", "Treatment.Freq": "weekly", "Subject.Race": "NAN", "Subject.Disorder": "NAN", "Treatment.Time_elapsed": "NAN", "Treatment.Dosage": "different doses", "Subject.Population": "NAN", "Subject.Gender": "NAN", "Combination.Drug": "NAN", "Treatment.Duration": "NAN", "Treatment.Drug": "pegylated interferon alfa-2b"}]}