{"instruction": "You are an expert in event argument extraction. Please extract event arguments and their roles from the input that conform to the schema definition, which already includes event trigger words. If an argument does not exist, return NAN or an empty dictionary. Please respond in the format of a JSON string.", "schema": [{"event_type": "adverse event", "arguments": ["Treatment.Freq", "Treatment.Duration", "Treatment.Dosage", "Treatment.Drug", "Subject.Race", "Subject.Population", "Subject.Disorder", "Treatment.Disorder", "Subject", "Subject.Gender", "Effect", "Treatment.Time_elapsed", "Combination.Drug", "Subject.Age", "Treatment.Route"]}], "input": "Approximately 15 min after the first administration of nebulised morphine the patient became markedly bradypneic (respiratory rate: 4-5 bpm), hypotensive (BP 70/40 mmHg), and responded only partially to command."}
{"adverse event": [{"Treatment.Freq": "NAN", "Treatment.Duration": "NAN", "Treatment.Dosage": "NAN", "Treatment.Drug": "morphine", "Subject.Race": "NAN", "Subject.Population": "NAN", "Subject.Disorder": "NAN", "Treatment.Disorder": "NAN", "Subject": "patient", "Subject.Gender": "NAN", "Effect": "markedly bradypneic (respiratory rate: 4-5 bpm), hypotensive (BP 70/40 mmHg), and responded only partially to command", "Treatment.Time_elapsed": "15 min", "Combination.Drug": "NAN", "Subject.Age": "NAN", "Treatment.Route": "nebulised"}]}