{"instruction": "You are an expert in event extraction. Please extract events from the input that conform to the schema definition. Return an empty list for events that do not exist, and return NAN for arguments that do not exist. If an argument has multiple values, please return a list. Respond in the format of a JSON string.", "schema": [{"event_type": "adverse event", "trigger": true, "arguments": ["Subject.Age", "Treatment.Dosage", "Treatment.Route", "Treatment.Drug", "Combination.Drug", "Treatment", "Subject", "Subject.Population", "Treatment.Time_elapsed", "Subject.Race", "Effect", "Subject.Disorder", "Treatment.Freq", "Treatment.Duration", "Treatment.Disorder", "Subject.Gender"]}, {"event_type": "potential therapeutic event", "trigger": true, "arguments": ["Subject.Gender", "Subject.Age", "Subject", "Treatment.Duration", "Treatment.Route", "Treatment.Freq", "Treatment.Disorder", "Combination.Drug", "Treatment.Time_elapsed", "Subject.Population", "Treatment.Drug", "Subject.Race", "Subject.Disorder"]}], "input": "Drug interactions between macrolide antibiotics such as erythomycin and pharmacologic agents that prolong the QT interval have been known to cause TdP. However, clarithromycin is thought to be less frequently associated with drug induced TdP, because it inactivates hepatic cytochrome P-450 to a lesser extent than erythromycin."}
{"adverse event": [{"trigger": "cause ", "arguments": {"Subject.Age": "NAN", "Treatment.Dosage": "NAN", "Treatment.Route": "NAN", "Treatment.Drug": ["macrolide antibiotics", "pharmacologic agents", "erythomycin"], "Combination.Drug": ["pharmacologic agents", "erythomycin"], "Treatment": "Drug interactions between macrolide antibiotics such as erythomycin and pharmacologic agents that prolong the QT interval", "Subject": "NAN", "Subject.Population": "NAN", "Treatment.Time_elapsed": "NAN", "Subject.Race": "NAN", "Effect": "TdP.", "Subject.Disorder": "NAN", "Treatment.Freq": "NAN", "Treatment.Duration": "NAN", "Treatment.Disorder": "NAN", "Subject.Gender": "NAN"}}], "potential therapeutic event": []}