{"instruction": "You are an expert in event argument extraction. Please extract event arguments and their roles from the input that conform to the schema definition, which already includes event trigger words. If an argument does not exist, return NAN or an empty dictionary. Please respond in the format of a JSON string.", "schema": [{"event_type": "potential therapeutic event", "arguments": ["Subject.Disorder", "Effect", "Subject.Age", "Combination.Drug", "Treatment.Dosage", "Subject.Race", "Subject", "Treatment.Duration", "Subject.Gender", "Treatment.Time_elapsed", "Treatment.Route", "Treatment.Drug", "Treatment.Freq"]}], "input": "However, continued low-dose MTX led, in spite of normal liver tests, 8 years after the last biopsy to liver failure and death in 1 of our patients."}
{"potential therapeutic event": []}