{"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "The current report describes a man who was prescribed zonisamide for epilepsy and subsequently developed widespread skin rash , acute kidney injury , high - grade fever , eosinophilia , liver dysfunction , lymphadenopathy and an increase in antihuman herpesvirus-6 immunoglobulin G titer ."}
{"adverse effect": [{"subject": "skin rash", "object": "zonisamide"}, {"subject": "acute kidney injury", "object": "zonisamide"}, {"subject": "high - grade fever", "object": "zonisamide"}, {"subject": "eosinophilia", "object": "zonisamide"}, {"subject": "liver dysfunction", "object": "zonisamide"}, {"subject": "lymphadenopathy", "object": "zonisamide"}, {"subject": "an increase in antihuman herpesvirus-6 immunoglobulin G titer", "object": "zonisamide"}]}