{"instruction": "You are an expert in event extraction. Please extract events from the input that conform to the schema definition. Return an empty list for events that do not exist, and return NAN for arguments that do not exist. If an argument has multiple values, please return a list. Respond in the format of a JSON string.", "schema": [{"event_type": "adverse event", "trigger": true, "arguments": ["Subject.Age", "Subject.Gender", "Treatment.Time_elapsed", "Treatment.Disorder", "Combination.Drug", "Effect", "Treatment.Route", "Treatment.Freq", "Treatment.Duration", "Treatment.Dosage", "Subject.Population", "Subject.Disorder", "Treatment", "Subject", "Treatment.Drug", "Subject.Race"]}, {"event_type": "potential therapeutic event", "trigger": true, "arguments": ["Subject.Gender", "Treatment.Duration", "Effect", "Subject.Population", "Treatment.Dosage", "Treatment.Time_elapsed", "Treatment.Freq", "Subject", "Treatment.Drug", "Treatment.Disorder", "Treatment", "Subject.Race", "Subject.Age", "Combination.Drug", "Subject.Disorder", "Treatment.Route"]}], "input": "Antithyroid treatment with propylthiouracil (PTU) resulted in elevated hepatic enzymes and after the 12th week of pregnancy treatment was changed to carbimazole (CBZ)."}
{"adverse event": [{"trigger": "resulted ", "arguments": {"Subject.Age": "NAN", "Subject.Gender": "NAN", "Treatment.Time_elapsed": "NAN", "Treatment.Disorder": "NAN", "Combination.Drug": "NAN", "Effect": "elevated hepatic enzymes", "Treatment.Route": "NAN", "Treatment.Freq": "NAN", "Treatment.Duration": "NAN", "Treatment.Dosage": "NAN", "Subject.Population": "NAN", "Subject.Disorder": "pregnancy", "Treatment": "propylthiouracil (PTU)", "Subject": "12th week of pregnancy", "Treatment.Drug": "propylthiouracil", "Subject.Race": "NAN"}}], "potential therapeutic event": []}