{"instruction": "You are an expert in event argument extraction. Please extract event arguments and their roles from the input that conform to the schema definition, which already includes event trigger words. If an argument does not exist, return NAN or an empty dictionary. Please respond in the format of a JSON string.", "schema": [{"event_type": "adverse event", "arguments": ["Subject.Population", "Combination.Drug", "Treatment.Route", "Subject.Race", "Treatment.Time_elapsed", "Treatment.Duration", "Subject.Gender", "Subject.Age", "Treatment.Drug", "Effect", "Subject", "Treatment.Disorder", "Subject.Disorder", "Treatment.Freq", "Treatment", "Treatment.Dosage"]}], "input": "This article reports the case of an otherwise healthy patient who experienced permanent sensorineural hearing loss after a brief course of naproxen and reviews the literature on NSAID-related permanent sensorineural hearing loss."}
{"adverse event": [{"Subject.Population": "NAN", "Combination.Drug": "NAN", "Treatment.Route": "NAN", "Subject.Race": "NAN", "Treatment.Time_elapsed": "NAN", "Treatment.Duration": "brief course", "Subject.Gender": "NAN", "Subject.Age": "NAN", "Treatment.Drug": "naproxen", "Effect": "permanent sensorineural hearing loss", "Subject": "an otherwise healthy patient", "Treatment.Disorder": "NAN", "Subject.Disorder": "NAN", "Treatment.Freq": "NAN", "Treatment": "a brief course of naproxen", "Treatment.Dosage": "NAN"}]}