{"instruction": "You are an expert in named entity recognition. Please extract entities that match the schema definition from the input. Return an empty list if the entity type does not exist. Please respond in the format of a JSON string.", "schema": ["GENE"], "input": "MEKs and ERKs inhibited IL - 6 activation of Stat3 harboring a mutation at serine - 727 , the major site for serine phosphorylation , similar to inhibition of wild - type Stat3 , and inhibited Janus kinases Jak1 and Jak2 upstream of Stat3 in the Jak - STAT - signaling pathway ."}
{"GENE": ["MEKs", "ERKs", "IL - 6", "Stat3", "wild - type Stat3", "Janus kinases", "Jak1", "Jak", "Jak2", "STAT"]}