{"instruction": "You are an expert in event argument extraction. Please extract event arguments and their roles from the input that conform to the schema definition, which already includes event trigger words. If an argument does not exist, return NAN or an empty dictionary. Please respond in the format of a JSON string.", "schema": [{"event_type": "adverse event", "arguments": ["Subject.Disorder", "Treatment.Drug", "Treatment", "Treatment.Dosage", "Subject", "Treatment.Route", "Treatment.Time_elapsed", "Effect", "Subject.Age", "Subject.Population", "Treatment.Disorder", "Treatment.Freq", "Subject.Gender", "Combination.Drug", "Subject.Race", "Treatment.Duration"]}], "input": "Thiopurine methyltransferase deficiency occurs at a frequency of one in 300 and is associated with profound myelosuppression after a short course of azathioprine."}
{"adverse event": [{"Subject.Disorder": "NAN", "Treatment.Drug": "azathioprine", "Treatment": "a short course of azathioprine", "Treatment.Dosage": "NAN", "Subject": "NAN", "Treatment.Route": "NAN", "Treatment.Time_elapsed": "a short course", "Effect": "profound myelosuppression", "Subject.Age": "NAN", "Subject.Population": "NAN", "Treatment.Disorder": "NAN", "Treatment.Freq": "NAN", "Subject.Gender": "NAN", "Combination.Drug": "NAN", "Subject.Race": "NAN", "Treatment.Duration": "NAN"}]}