{"instruction": "You are an expert in event argument extraction. Please extract event arguments and their roles from the input that conform to the schema definition, which already includes event trigger words. If an argument does not exist, return NAN or an empty dictionary. Please respond in the format of a JSON string.", "schema": [{"event_type": "adverse event", "arguments": ["Treatment.Route", "Treatment", "Effect", "Treatment.Freq", "Treatment.Duration", "Treatment.Time_elapsed", "Treatment.Drug", "Treatment.Dosage", "Subject", "Subject.Population", "Treatment.Disorder", "Subject.Gender", "Subject.Age", "Combination.Drug", "Subject.Race"]}], "input": "It was postulated that the allergic reaction was most likely caused by capecitabine or the intermediate metabolites based on the immediate reappearance of symptoms from the rechallenge, pharmacokinetic data, and well-tolerance of fluorouracil."}
{"adverse event": [{"Treatment.Route": "NAN", "Treatment": "capecitabine or the intermediate metabolites", "Effect": "allergic reaction", "Treatment.Freq": "NAN", "Treatment.Duration": "NAN", "Treatment.Time_elapsed": "NAN", "Treatment.Drug": "capecitabine", "Treatment.Dosage": "NAN", "Subject": "NAN", "Subject.Population": "NAN", "Treatment.Disorder": "NAN", "Subject.Gender": "NAN", "Subject.Age": "NAN", "Combination.Drug": "NAN", "Subject.Race": "NAN"}]}