{"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "We report 5 patients ( 3 patients with chronic hepatitis C treated with pegylated interferon alfa-2b in association with oral ribavirin and two patients with chronic myelocytic leukemia ) who developed local cutaneous reactions at sites of injection after the administration of weekly subcutaneous injections of pegylated interferon alfa-2b at different doses ."}
{"adverse effect": [{"subject": "local cutaneous reactions", "object": "pegylated interferon alfa-2b"}, {"subject": "local cutaneous reactions", "object": "ribavirin"}]}