{"instruction": "You are an expert in event extraction. Please extract events from the input that conform to the schema definition. Return an empty list for events that do not exist, and return NAN for arguments that do not exist. If an argument has multiple values, please return a list. Respond in the format of a JSON string.", "schema": [{"event_type": "adverse event", "trigger": true, "arguments": ["Combination.Drug", "Treatment.Dosage", "Subject.Race", "Subject.Population", "Subject.Disorder", "Subject.Gender", "Subject", "Treatment.Disorder", "Subject.Age", "Treatment", "Treatment.Drug", "Effect", "Treatment.Duration", "Treatment.Freq", "Treatment.Route", "Treatment.Time_elapsed"]}, {"event_type": "potential therapeutic event", "trigger": true, "arguments": ["Subject.Disorder", "Treatment.Dosage", "Treatment.Duration", "Treatment.Drug", "Treatment.Time_elapsed", "Treatment.Freq", "Treatment.Route", "Treatment", "Subject.Age", "Subject.Race", "Effect", "Subject.Gender", "Subject", "Combination.Drug", "Subject.Population"]}], "input": "We describe a patient with a liver abscess due to Entamoeba histolytica, in whom metronidazole therapy (total dose, 21 g over 14 days) was complicated by reversible deafness, tinnitus, and ataxia and who relapsed 5 months later with a splenic abscess."}
{"adverse event": [{"trigger": "complicated ", "arguments": {"Combination.Drug": "NAN", "Treatment.Dosage": "21 g", "Subject.Race": "NAN", "Subject.Population": "NAN", "Subject.Disorder": "NAN", "Subject.Gender": "NAN", "Subject": "a patient with a liver abscess due to Entamoeba histolytica", "Treatment.Disorder": ["liver abscess", "Entamoeba histolytica"], "Subject.Age": "NAN", "Treatment": "metronidazole therapy (total dose, 21 g over 14 days)", "Treatment.Drug": "metronidazole", "Effect": "reversible deafness, tinnitus, and ataxia and who relapsed 5 months later with a splenic abscess", "Treatment.Duration": "14 days", "Treatment.Freq": "NAN", "Treatment.Route": "NAN", "Treatment.Time_elapsed": "NAN"}}], "potential therapeutic event": []}