{"instruction": "You are an expert in event extraction. Please extract events from the input that conform to the schema definition. Return an empty list for events that do not exist, and return NAN for arguments that do not exist. If an argument has multiple values, please return a list. Respond in the format of a JSON string.", "schema": [{"event_type": "adverse event", "trigger": true, "arguments": ["Treatment.Freq", "Subject", "Subject.Gender", "Effect", "Treatment.Disorder", "Subject.Population", "Treatment.Route", "Treatment.Dosage", "Treatment.Time_elapsed", "Combination.Drug", "Subject.Disorder", "Treatment.Drug", "Subject.Race", "Subject.Age", "Treatment", "Treatment.Duration"]}, {"event_type": "potential therapeutic event", "trigger": true, "arguments": ["Subject.Age", "Subject.Disorder", "Treatment.Disorder", "Subject", "Treatment", "Subject.Gender", "Effect", "Combination.Drug", "Treatment.Route", "Treatment.Duration", "Treatment.Freq", "Subject.Population", "Treatment.Drug"]}], "input": "Only after three subsequent episodes of severe, symptomatic thrombocytopenia over the next four weeks did he say, upon repeat questioning, that he had continued to take quinine for night leg cramps."}
{"adverse event": [{"trigger": "take ", "arguments": {"Treatment.Freq": "NAN", "Subject": ["night leg cramps", "he"], "Subject.Gender": "he", "Effect": "symptomatic thrombocytopenia", "Treatment.Disorder": "night leg cramps", "Subject.Population": "NAN", "Treatment.Route": "NAN", "Treatment.Dosage": "NAN", "Treatment.Time_elapsed": "over the next four weeks", "Combination.Drug": "NAN", "Subject.Disorder": "NAN", "Treatment.Drug": "quinine", "Subject.Race": "NAN", "Subject.Age": "NAN", "Treatment": "continued to take quinine", "Treatment.Duration": "NAN"}}], "potential therapeutic event": []}