{"instruction": "You are an expert in event extraction. Please extract events from the input that conform to the schema definition. Return an empty list for events that do not exist, and return NAN for arguments that do not exist. If an argument has multiple values, please return a list. Respond in the format of a JSON string.", "schema": [{"event_type": "potential therapeutic event", "trigger": true, "arguments": ["Subject.Gender", "Subject.Age", "Effect", "Treatment.Duration", "Treatment", "Subject", "Subject.Disorder", "Subject.Population", "Treatment.Dosage", "Subject.Race", "Treatment.Drug", "Treatment.Time_elapsed", "Treatment.Freq"]}, {"event_type": "adverse event", "trigger": true, "arguments": ["Treatment.Dosage", "Subject.Population", "Effect", "Treatment.Freq", "Treatment.Route", "Combination.Drug", "Subject.Disorder", "Subject", "Treatment.Duration", "Treatment.Drug", "Treatment.Disorder", "Treatment", "Treatment.Time_elapsed", "Subject.Age", "Subject.Gender", "Subject.Race"]}], "input": "In eight patients, a mean decrease in serum Na+ of 8.25 +/- 3.2 mEq/L was observed after a single 200 mg intravenous dose of lorcainide."}
{"potential therapeutic event": [], "adverse event": [{"trigger": "observed ", "arguments": {"Treatment.Dosage": "a single 200 mg", "Subject.Population": "eight", "Effect": "mean decrease in serum Na+ of 8.25 +/- 3.2 mEq/L", "Treatment.Freq": "NAN", "Treatment.Route": "intravenous", "Combination.Drug": "NAN", "Subject.Disorder": "NAN", "Subject": "eight patients", "Treatment.Duration": "NAN", "Treatment.Drug": "lorcainide", "Treatment.Disorder": "NAN", "Treatment": "a single 200 mg intravenous dose of lorcainide", "Treatment.Time_elapsed": "NAN", "Subject.Age": "NAN", "Subject.Gender": "NAN", "Subject.Race": "NAN"}}]}