{"instruction": "You are an expert in event argument extraction. Please extract event arguments and their roles from the input that conform to the schema definition, which already includes event trigger words. If an argument does not exist, return NAN or an empty dictionary. Please respond in the format of a JSON string.", "schema": [{"event_type": "adverse event", "arguments": ["Subject.Population", "Subject.Disorder", "Treatment.Drug", "Treatment.Disorder", "Treatment.Freq", "Treatment", "Treatment.Route", "Treatment.Time_elapsed", "Treatment.Duration", "Subject.Gender", "Effect", "Subject.Race", "Subject.Age", "Treatment.Dosage"]}], "input": "CONCLUSION: Significant ocular complications such as an irreversible decrease of visual acuity may develop in patients treated with pegylated interferon."}
{"adverse event": [{"Subject.Population": "NAN", "Subject.Disorder": "NAN", "Treatment.Drug": "pegylated interferon", "Treatment.Disorder": "NAN", "Treatment.Freq": "NAN", "Treatment": "pegylated interferon", "Treatment.Route": "NAN", "Treatment.Time_elapsed": "NAN", "Treatment.Duration": "NAN", "Subject.Gender": "NAN", "Effect": "irreversible decrease of visual acuity", "Subject.Race": "NAN", "Subject.Age": "NAN", "Treatment.Dosage": "NAN"}]}