{"instruction": "You are an expert in event extraction. Please extract events from the input that conform to the schema definition. Return an empty list for events that do not exist, and return NAN for arguments that do not exist. If an argument has multiple values, please return a list. Respond in the format of a JSON string.", "schema": [{"event_type": "adverse event", "trigger": true, "arguments": ["Treatment", "Treatment.Dosage", "Subject.Age", "Treatment.Drug", "Subject.Gender", "Combination.Drug", "Treatment.Disorder", "Treatment.Duration", "Subject.Disorder", "Treatment.Freq", "Subject.Race", "Subject", "Subject.Population", "Effect", "Treatment.Time_elapsed", "Treatment.Route"]}, {"event_type": "potential therapeutic event", "trigger": true, "arguments": ["Subject.Disorder", "Treatment.Route", "Treatment", "Treatment.Dosage", "Subject", "Treatment.Disorder", "Subject.Race", "Subject.Gender", "Subject.Population", "Combination.Drug", "Effect", "Treatment.Time_elapsed"]}], "input": "We report 5 patients (3 patients with chronic hepatitis C treated with pegylated interferon alfa-2b in association with oral ribavirin and two patients with chronic myelocytic leukemia) who developed local cutaneous reactions at sites of injection after the administration of weekly subcutaneous injections of pegylated interferon alfa-2b at different doses."}
{"adverse event": [{"trigger": "developed ", "arguments": {"Treatment": "administration of weekly subcutaneous injections of pegylated interferon alfa-2b at different doses", "Treatment.Dosage": "different doses", "Subject.Age": "NAN", "Treatment.Drug": "pegylated interferon alfa-2b", "Subject.Gender": "NAN", "Combination.Drug": "NAN", "Treatment.Disorder": "chronic myelocytic leukemia", "Treatment.Duration": "NAN", "Subject.Disorder": "NAN", "Treatment.Freq": "weekly", "Subject.Race": "NAN", "Subject": "two patients with chronic myelocytic leukemia", "Subject.Population": "NAN", "Effect": "local cutaneous reactions at sites of injection", "Treatment.Time_elapsed": "NAN", "Treatment.Route": "subcutaneous injections"}}], "potential therapeutic event": []}