{"instruction": "You are an expert in named entity recognition. Please extract entities that match the schema definition from the input. Return an empty list if the entity type does not exist. Please respond in the format of a JSON string.", "schema": ["GENE"], "input": "The different holoenzyme RNA polymerases generated upon reconstituting these mutants independently with core RNA polymerase ( alpha2beta beta ' ) have shown reduced transcriptional activity in comparison to the enzyme containing wild - type sigma factor ."}
{"GENE": ["holoenzyme RNA polymerases", "core RNA polymerase", "alpha2beta beta '", "wild - type sigma factor"]}