{"instruction": "You are an expert in event extraction. Please extract events from the input that conform to the schema definition. Return an empty list for events that do not exist, and return NAN for arguments that do not exist. If an argument has multiple values, please return a list. Respond in the format of a JSON string.", "schema": [{"event_type": "potential therapeutic event", "trigger": true, "arguments": ["Effect", "Treatment.Dosage", "Treatment.Disorder", "Treatment.Drug", "Treatment", "Treatment.Duration", "Combination.Drug", "Subject.Race", "Subject.Gender", "Treatment.Freq", "Subject", "Treatment.Route", "Subject.Population", "Subject.Age"]}, {"event_type": "adverse event", "trigger": true, "arguments": ["Subject.Race", "Subject", "Treatment.Route", "Treatment.Disorder", "Subject.Disorder", "Combination.Drug", "Subject.Age", "Effect", "Subject.Population", "Treatment.Freq", "Subject.Gender", "Treatment.Dosage", "Treatment.Time_elapsed", "Treatment", "Treatment.Duration", "Treatment.Drug"]}], "input": "CASE PRESENTATION: We report a patient with CF who developed recurrent eosinophilia and severe persistent bronchospasm following repeated administration of preservative-free tobramycin by inhalation, beginning at 16 months of age."}
{"potential therapeutic event": [], "adverse event": [{"trigger": "developed ", "arguments": {"Subject.Race": "NAN", "Subject": ["beginning at 16 months of age", "a patient with CF"], "Treatment.Route": "inhalation", "Treatment.Disorder": "CF", "Subject.Disorder": "NAN", "Combination.Drug": "NAN", "Subject.Age": "16 months", "Effect": "recurrent eosinophilia and severe persistent bronchospasm", "Subject.Population": "NAN", "Treatment.Freq": "NAN", "Subject.Gender": "NAN", "Treatment.Dosage": "NAN", "Treatment.Time_elapsed": "NAN", "Treatment": "repeated administration of preservative-free tobramycin by inhalation", "Treatment.Duration": "NAN", "Treatment.Drug": "tobramycin"}}]}