{"instruction": "You are an expert in event extraction. Please extract events from the input that conform to the schema definition. Return an empty list for events that do not exist, and return NAN for arguments that do not exist. If an argument has multiple values, please return a list. Respond in the format of a JSON string.", "schema": [{"event_type": "adverse event", "trigger": true, "arguments": ["Subject.Disorder", "Treatment.Disorder", "Treatment.Time_elapsed", "Subject.Population", "Treatment.Duration", "Treatment.Freq", "Treatment.Dosage", "Effect", "Subject.Gender", "Subject", "Subject.Race", "Treatment", "Combination.Drug", "Treatment.Drug", "Subject.Age"]}, {"event_type": "potential therapeutic event", "trigger": true, "arguments": ["Subject.Population", "Subject.Gender", "Treatment.Time_elapsed", "Subject.Age", "Treatment.Route", "Subject", "Combination.Drug", "Treatment.Disorder", "Treatment.Drug", "Subject.Race", "Treatment.Dosage", "Subject.Disorder", "Treatment", "Treatment.Duration", "Treatment.Freq"]}], "input": "1.\nArtelinic acid (AL), a water-soluble artemisinin analogue for treatment of multidrug resistant malaria, is metabolized to the active metabolite dihydroqinghaosu (DQHS) solely by  CYP3A4/5."}
{"adverse event": [], "potential therapeutic event": [{"trigger": "treatment ", "arguments": {"Subject.Population": "NAN", "Subject.Gender": "NAN", "Treatment.Time_elapsed": "NAN", "Subject.Age": "NAN", "Treatment.Route": "NAN", "Subject": "NAN", "Combination.Drug": "NAN", "Treatment.Disorder": "multidrug resistant malaria", "Treatment.Drug": "Artelinic acid", "Subject.Race": "NAN", "Treatment.Dosage": "NAN", "Subject.Disorder": "NAN", "Treatment": "Artelinic acid (AL), a water-soluble artemisinin analogue", "Treatment.Duration": "NAN", "Treatment.Freq": "NAN"}}]}