{"instruction": "You are an expert in named entity recognition. Please extract entities that match the schema definition from the input. Return an empty list if the entity type does not exist. Please respond in the format of a JSON string.", "schema": ["Chemical"], "input": "We explored the role of ER - stress as a general mechanism of toxicity by utilizing a high - throughput in vitro assay to screen 316 chemically diverse Pfizer proprietary compounds with known in vivo toxicity outcome for nuclear accumulation of spliced x - box binding protein 1 ( XBP1s ) , a key transcription factor of the unfolded protein response ( UPR ) ."}
{"Chemical": []}