{"instruction": "You are an expert in event argument extraction. Please extract event arguments and their roles from the input that conform to the schema definition, which already includes event trigger words. If an argument does not exist, return NAN or an empty dictionary. Please respond in the format of a JSON string.", "schema": [{"event_type": "potential therapeutic event", "arguments": ["Subject.Population", "Treatment.Route", "Treatment.Freq", "Subject.Disorder", "Combination.Drug", "Treatment.Drug", "Subject", "Subject.Race", "Treatment.Time_elapsed", "Treatment.Duration", "Treatment.Dosage", "Treatment.Disorder", "Treatment", "Subject.Age", "Effect"]}], "input": "We conclude that quinine does not improve the survival of adult patients with de novo AML, even though it improves CR rate in a small subgroup of patients defined by rhodamine 123 efflux."}
{"potential therapeutic event": [{"Subject.Population": "a small subgroup", "Treatment.Route": "NAN", "Treatment.Freq": "NAN", "Subject.Disorder": "rhodamine 123 efflux", "Combination.Drug": "NAN", "Treatment.Drug": "quinine", "Subject": "a small subgroup of patients defined by rhodamine 123 efflux", "Subject.Race": "NAN", "Treatment.Time_elapsed": "NAN", "Treatment.Duration": "NAN", "Treatment.Dosage": "NAN", "Treatment.Disorder": "de novo AML", "Treatment": "quinine", "Subject.Age": "NAN", "Effect": "improves CR rate"}]}