{"instruction": "You are an expert in event argument extraction. Please extract event arguments and their roles from the input that conform to the schema definition, which already includes event trigger words. If an argument does not exist, return NAN or an empty dictionary. Please respond in the format of a JSON string.", "schema": [{"event_type": "potential therapeutic event", "arguments": ["Treatment.Freq", "Treatment.Drug", "Treatment.Dosage", "Effect", "Subject.Race", "Subject.Disorder", "Treatment.Disorder", "Treatment.Route", "Treatment.Duration", "Subject.Gender", "Combination.Drug", "Treatment.Time_elapsed", "Treatment", "Subject.Population"]}], "input": "These findings suggest that the corneal and retinal changes are the result of a toxic effect of tamoxifen when used in the doses and duration described."}
{"potential therapeutic event": []}