{"instruction": "You are an expert in event argument extraction. Please extract event arguments and their roles from the input that conform to the schema definition, which already includes event trigger words. If an argument does not exist, return NAN or an empty dictionary. Please respond in the format of a JSON string.", "schema": [{"event_type": "potential therapeutic event", "arguments": ["Treatment.Dosage", "Effect", "Subject.Disorder", "Subject", "Treatment.Duration", "Treatment.Disorder", "Treatment.Drug", "Subject.Population", "Subject.Gender", "Combination.Drug", "Treatment.Time_elapsed", "Treatment.Freq", "Subject.Race"]}], "input": "Although use of the Naranjo adverse reaction probability scale indicated a probable relationship (score of 6) between the patient's development of methotrexate toxicity and omeprazole use, we believe this was a drug-drug interaction case consistent with previous reports in the literature."}
{"potential therapeutic event": []}