{"instruction": "You are an expert in event extraction. Please extract events from the input that conform to the schema definition. Return an empty list for events that do not exist, and return NAN for arguments that do not exist. If an argument has multiple values, please return a list. Respond in the format of a JSON string.", "schema": [{"event_type": "adverse event", "trigger": true, "arguments": ["Treatment.Drug", "Subject", "Treatment.Disorder", "Combination.Drug", "Subject.Race", "Subject.Disorder", "Subject.Population", "Effect", "Treatment.Duration", "Treatment.Dosage", "Subject.Age", "Treatment.Route", "Treatment", "Treatment.Freq", "Subject.Gender", "Treatment.Time_elapsed"]}, {"event_type": "potential therapeutic event", "trigger": true, "arguments": ["Combination.Drug", "Treatment.Route", "Subject.Age", "Treatment.Time_elapsed", "Treatment", "Effect", "Subject.Gender", "Treatment.Dosage", "Treatment.Duration", "Subject.Population", "Subject", "Subject.Race", "Treatment.Drug", "Treatment.Disorder", "Subject.Disorder"]}], "input": "In addition to disease refractoriness, rare instances of disease progression from chronic phase to blast crisis during imatinib therapy have recently been anecdotally reported."}
{"adverse event": [{"trigger": "during ", "arguments": {"Treatment.Drug": "imatinib", "Subject": "NAN", "Treatment.Disorder": "NAN", "Combination.Drug": "NAN", "Subject.Race": "NAN", "Subject.Disorder": "NAN", "Subject.Population": "NAN", "Effect": "disease progression from chronic phase to blast crisis", "Treatment.Duration": "NAN", "Treatment.Dosage": "NAN", "Subject.Age": "NAN", "Treatment.Route": "NAN", "Treatment": "imatinib therapy", "Treatment.Freq": "NAN", "Subject.Gender": "NAN", "Treatment.Time_elapsed": "NAN"}}], "potential therapeutic event": []}