{"instruction": "You are an expert in named entity recognition. Please extract entities that match the schema definition from the input. Return an empty list if the entity type does not exist. Please respond in the format of a JSON string.", "schema": ["GENE"], "input": "Mutational analyses have demonstrated the importance of sequences within the 327 bp segment that contain a putative cyclic AMP responsive element binding protein ( CREB ) binding site for TGF - beta 1 and PMA responsiveness and putative PU - 1 and Sp1 binding sites for basal promoter activity ."}
{"GENE": ["cyclic AMP responsive element binding protein", "CREB", "TGF - beta 1", "PU - 1", "Sp1 binding sites"]}