{"instruction": "You are an expert in event argument extraction. Please extract event arguments and their roles from the input that conform to the schema definition, which already includes event trigger words. If an argument does not exist, return NAN or an empty dictionary. Please respond in the format of a JSON string.", "schema": [{"event_type": "adverse event", "arguments": ["Combination.Drug", "Subject.Age", "Treatment.Dosage", "Treatment.Drug", "Treatment.Time_elapsed", "Subject.Race", "Treatment.Freq", "Treatment", "Effect", "Subject", "Treatment.Disorder", "Subject.Disorder", "Treatment.Duration", "Subject.Gender", "Subject.Population", "Treatment.Route"]}], "input": "One patient developed large intramural esophageal hematoma as a complication of heparin therapy."}
{"adverse event": [{"Combination.Drug": "NAN", "Subject.Age": "NAN", "Treatment.Dosage": "NAN", "Treatment.Drug": "heparin", "Treatment.Time_elapsed": "NAN", "Subject.Race": "NAN", "Treatment.Freq": "NAN", "Treatment": "a complication of heparin therapy", "Effect": "large intramural esophageal hematoma", "Subject": "One patient", "Treatment.Disorder": "NAN", "Subject.Disorder": "NAN", "Treatment.Duration": "NAN", "Subject.Gender": "NAN", "Subject.Population": "NAN", "Treatment.Route": "NAN"}]}