{"instruction": "You are an expert in event extraction. Please extract events from the input that conform to the schema definition. Return an empty list for events that do not exist, and return NAN for arguments that do not exist. If an argument has multiple values, please return a list. Respond in the format of a JSON string.", "schema": [{"event_type": "potential therapeutic event", "trigger": true, "arguments": ["Treatment.Route", "Subject.Race", "Treatment.Freq", "Subject.Age", "Treatment", "Combination.Drug", "Treatment.Duration", "Treatment.Drug", "Treatment.Disorder", "Treatment.Dosage", "Treatment.Time_elapsed", "Subject.Gender", "Subject.Population", "Subject.Disorder"]}, {"event_type": "adverse event", "trigger": true, "arguments": ["Treatment.Freq", "Subject.Race", "Treatment.Drug", "Treatment.Dosage", "Treatment.Route", "Subject.Gender", "Combination.Drug", "Treatment.Disorder", "Effect", "Subject.Population", "Treatment.Duration", "Treatment.Time_elapsed", "Subject.Disorder", "Treatment", "Subject.Age", "Subject"]}], "input": "The use of telithromycin in patients receiving multiple doses of oxycodone for pain relief may increase the risk of opioid adverse effects."}
{"potential therapeutic event": [], "adverse event": [{"trigger": "increase the risk ", "arguments": {"Treatment.Freq": "NAN", "Subject.Race": "NAN", "Treatment.Drug": "telithromycin", "Treatment.Dosage": "NAN", "Treatment.Route": "NAN", "Subject.Gender": "NAN", "Combination.Drug": "NAN", "Treatment.Disorder": "NAN", "Effect": "opioid adverse effects", "Subject.Population": "NAN", "Treatment.Duration": "NAN", "Treatment.Time_elapsed": "NAN", "Subject.Disorder": "NAN", "Treatment": "telithromycin", "Subject.Age": "NAN", "Subject": "patients receiving multiple doses of oxycodone for pain relief"}}]}