{"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "The chemotherapeutics , including vincristine , actinomycin D , and epirubicin in case 1 and vincristine and actinomycin D in case 2 , were given before the hepatotoxicity developed ."}
{"adverse effect": [{"subject": "hepatotoxicity", "object": "vincristine"}, {"subject": "hepatotoxicity", "object": "actinomycin D"}, {"subject": "hepatotoxicity", "object": "epirubicin"}]}