{"instruction": "You are an expert in event extraction. Please extract events from the input that conform to the schema definition. Return an empty list for events that do not exist, and return NAN for arguments that do not exist. If an argument has multiple values, please return a list. Respond in the format of a JSON string.", "schema": [{"event_type": "potential therapeutic event", "trigger": true, "arguments": ["Treatment", "Subject.Age", "Treatment.Route", "Subject.Population", "Subject.Race", "Treatment.Duration", "Treatment.Disorder", "Effect", "Subject.Gender", "Treatment.Dosage", "Treatment.Drug", "Treatment.Time_elapsed"]}, {"event_type": "adverse event", "trigger": true, "arguments": ["Treatment.Time_elapsed", "Subject.Race", "Treatment.Freq", "Treatment.Drug", "Subject", "Treatment.Route", "Treatment.Duration", "Subject.Disorder", "Subject.Gender", "Treatment.Dosage", "Subject.Age", "Treatment.Disorder", "Effect", "Combination.Drug", "Treatment", "Subject.Population"]}], "input": "OBJECTIVES: To describe the clinicopathologic features of 3 patients with CML who rapidly progressed from chronic phase to blast crisis while taking imatinib and to perform a review of the literature."}
{"potential therapeutic event": [], "adverse event": [{"trigger": "progressed ", "arguments": {"Treatment.Time_elapsed": "NAN", "Subject.Race": "NAN", "Treatment.Freq": "NAN", "Treatment.Drug": "imatinib", "Subject": "3 patients with CML", "Treatment.Route": "NAN", "Treatment.Duration": "NAN", "Subject.Disorder": "NAN", "Subject.Gender": "NAN", "Treatment.Dosage": "NAN", "Subject.Age": "NAN", "Treatment.Disorder": "CML", "Effect": "from chronic phase to blast crisis", "Combination.Drug": "NAN", "Treatment": "imatinib", "Subject.Population": "3"}}]}