{"instruction": "You are an expert in event extraction. Please extract events from the input that conform to the schema definition. Return an empty list for events that do not exist, and return NAN for arguments that do not exist. If an argument has multiple values, please return a list. Respond in the format of a JSON string.", "schema": [{"event_type": "potential therapeutic event", "trigger": true, "arguments": ["Treatment.Freq", "Effect", "Treatment.Duration", "Treatment.Disorder", "Treatment.Time_elapsed", "Treatment.Drug", "Treatment", "Treatment.Route", "Combination.Drug", "Subject", "Subject.Gender", "Subject.Population"]}, {"event_type": "adverse event", "trigger": true, "arguments": ["Subject", "Treatment.Route", "Subject.Population", "Subject.Age", "Subject.Race", "Treatment.Disorder", "Treatment.Time_elapsed", "Subject.Gender", "Treatment", "Subject.Disorder", "Treatment.Freq", "Treatment.Dosage", "Combination.Drug", "Treatment.Drug", "Effect", "Treatment.Duration"]}], "input": "Severe arrhythmia as a result of the interaction of cetirizine and pilsicainide in a patient with renal insufficiency: first case presentation showing competition for excretion via renal multidrug resistance protein 1 and organic cation transporter 2."}
{"potential therapeutic event": [], "adverse event": [{"trigger": "result ", "arguments": {"Subject": "a patient with renal insufficiency", "Treatment.Route": "NAN", "Subject.Population": "NAN", "Subject.Age": "NAN", "Subject.Race": "NAN", "Treatment.Disorder": "NAN", "Treatment.Time_elapsed": "NAN", "Subject.Gender": "NAN", "Treatment": "interaction of cetirizine and pilsicainide", "Subject.Disorder": "renal insufficiency", "Treatment.Freq": "NAN", "Treatment.Dosage": "NAN", "Combination.Drug": ["pilsicainide", "cetirizine"], "Treatment.Drug": ["pilsicainide", "cetirizine"], "Effect": "Severe arrhythmia", "Treatment.Duration": "NAN"}}]}