{"instruction": "You are an expert in event extraction. Please extract events from the input that conform to the schema definition. Return an empty list for events that do not exist, and return NAN for arguments that do not exist. If an argument has multiple values, please return a list. Respond in the format of a JSON string.", "schema": [{"event_type": "adverse event", "trigger": true, "arguments": ["Treatment.Freq", "Subject.Population", "Subject", "Subject.Disorder", "Treatment.Drug", "Effect", "Subject.Gender", "Treatment", "Combination.Drug", "Treatment.Duration", "Subject.Race", "Treatment.Route", "Treatment.Dosage"]}], "input": "This fourth type of cutaneous minocycline hyperpigmentation may be a variant of Type I, but based on clinical, pathological and microanalytical differences, appears to be a new entity."}
{"adverse event": [{"trigger": "be ", "arguments": {"Treatment.Freq": "NAN", "Subject.Population": "NAN", "Subject": "NAN", "Subject.Disorder": "NAN", "Treatment.Drug": "minocycline", "Effect": "hyperpigmentation", "Subject.Gender": "NAN", "Treatment": "minocycline", "Combination.Drug": "NAN", "Treatment.Duration": "NAN", "Subject.Race": "NAN", "Treatment.Route": "NAN", "Treatment.Dosage": "NAN"}}]}