{"instruction": "You are an expert in event extraction. Please extract events from the input that conform to the schema definition. Return an empty list for events that do not exist, and return NAN for arguments that do not exist. If an argument has multiple values, please return a list. Respond in the format of a JSON string.", "schema": [{"event_type": "potential therapeutic event", "trigger": true, "arguments": ["Subject.Population", "Treatment.Route", "Combination.Drug", "Subject.Race", "Subject.Gender", "Treatment", "Subject.Disorder", "Subject.Age", "Treatment.Time_elapsed", "Treatment.Duration", "Treatment.Disorder", "Treatment.Dosage", "Effect", "Subject", "Treatment.Drug"]}, {"event_type": "adverse event", "trigger": true, "arguments": ["Subject.Gender", "Treatment.Freq", "Treatment.Disorder", "Treatment.Drug", "Subject", "Combination.Drug", "Treatment.Duration", "Subject.Race", "Treatment.Time_elapsed", "Subject.Disorder", "Subject.Age", "Treatment.Dosage", "Treatment", "Treatment.Route", "Effect", "Subject.Population"]}], "input": "Clinical course of macular edema in two cases of interferon-associated retinopathy observed by optical coherence tomography."}
{"potential therapeutic event": [], "adverse event": [{"trigger": "associated ", "arguments": {"Subject.Gender": "NAN", "Treatment.Freq": "NAN", "Treatment.Disorder": "NAN", "Treatment.Drug": "interferon", "Subject": "two cases", "Combination.Drug": "NAN", "Treatment.Duration": "NAN", "Subject.Race": "NAN", "Treatment.Time_elapsed": "NAN", "Subject.Disorder": "NAN", "Subject.Age": "NAN", "Treatment.Dosage": "NAN", "Treatment": "interferon", "Treatment.Route": "NAN", "Effect": ["macular edema", "retinopathy"], "Subject.Population": "two"}}]}