{"instruction": "You are an expert in event extraction. Please extract events from the input that conform to the schema definition. Return an empty list for events that do not exist, and return NAN for arguments that do not exist. If an argument has multiple values, please return a list. Respond in the format of a JSON string.", "schema": [{"event_type": "adverse event", "trigger": true, "arguments": ["Subject.Disorder", "Subject.Age", "Treatment", "Treatment.Drug", "Treatment.Duration", "Subject.Race", "Subject.Gender", "Treatment.Time_elapsed", "Effect", "Treatment.Disorder", "Treatment.Dosage", "Treatment.Route", "Subject", "Treatment.Freq", "Combination.Drug"]}, {"event_type": "potential therapeutic event", "trigger": true, "arguments": ["Subject.Age", "Treatment.Drug", "Treatment.Disorder", "Treatment.Duration", "Subject.Gender", "Treatment.Dosage", "Subject.Race", "Subject.Disorder", "Treatment", "Subject", "Treatment.Freq", "Effect", "Treatment.Route", "Combination.Drug", "Subject.Population", "Treatment.Time_elapsed"]}], "input": "The CATAPULT I study shows that tirapazamine enhances the activity of cisplatin in patients with advanced NSCLC and confirms that hypoxia is an exploitable therapeutic target in human malignancies."}
{"adverse event": [], "potential therapeutic event": [{"trigger": "enhances ", "arguments": {"Subject.Age": "NAN", "Treatment.Drug": "tirapazamine", "Treatment.Disorder": "advanced NSCLC", "Treatment.Duration": "NAN", "Subject.Gender": "NAN", "Treatment.Dosage": "NAN", "Subject.Race": "NAN", "Subject.Disorder": "NAN", "Treatment": "tirapazamine", "Subject": "patients with advanced NSCLC", "Treatment.Freq": "NAN", "Effect": "enhances the activity of cisplatin", "Treatment.Route": "NAN", "Combination.Drug": "NAN", "Subject.Population": "NAN", "Treatment.Time_elapsed": "NAN"}}]}