{"instruction": "You are an expert in event argument extraction. Please extract event arguments and their roles from the input that conform to the schema definition, which already includes event trigger words. If an argument does not exist, return NAN or an empty dictionary. Please respond in the format of a JSON string.", "schema": [{"event_type": "adverse event", "arguments": ["Subject.Gender", "Treatment", "Subject", "Treatment.Duration", "Treatment.Freq", "Treatment.Disorder", "Subject.Disorder", "Effect", "Combination.Drug", "Treatment.Drug", "Treatment.Dosage", "Subject.Population", "Treatment.Time_elapsed", "Subject.Age", "Subject.Race"]}], "input": "Second cancers including various types of hematological malignancy have been reported in patients with hairy cell leukemia treated with chemotherapy or interferon alfa."}
{"adverse event": [{"Subject.Gender": "NAN", "Treatment": "chemotherapy or interferon alfa", "Subject": "patients with hairy cell leukemia", "Treatment.Duration": "NAN", "Treatment.Freq": "NAN", "Treatment.Disorder": "hairy cell leukemia", "Subject.Disorder": "NAN", "Effect": "Second cancers including various types of hematological malignancy", "Combination.Drug": "NAN", "Treatment.Drug": "interferon alfa", "Treatment.Dosage": "NAN", "Subject.Population": "NAN", "Treatment.Time_elapsed": "NAN", "Subject.Age": "NAN", "Subject.Race": "NAN"}]}