user55217: I get this error trying to upload avrdude: stk500v2_ReceiveMessage(): timeout
It is Robotdyn Mega 2560 PRO MINI and a Robotdyn CH340 which I have connected like this: 
I installed the CH340 drivers from here https://sparks.gogo.co.nz/ch340.html and I can see it in the device manager.
Connecting the Mega 2560 Pro Mini lights up the L and On LED but when pressing upload (testing with simple examples as Blink) I get the error and neither RX or TX lights up.
I have tried everything I can think of. What am I doing wrong?
I have confirmed that it is connected to the correct COM-port and I use these settings:
Board: Arduino/Genuino Mega or Mega 2560
Processor: ATMega2560 (Mega 2560)

I have also tried many different USB-cables, short and long, and USB 2.0 and USB 3.0 ports. I use Windows 10 64-bit.

user56461: Try placing a 100nf capacitor on RST. That is usually required on an FTDI programmer.
See Edgar's post - https://arduino.stackexchange.com/users/47431/edgar

55217: <p>I get this error trying to upload <code>avrdude: stk500v2_ReceiveMessage(): timeout</code></p>

<p>It is Robotdyn Mega 2560 PRO MINI and a Robotdyn CH340 which I have connected like this: <a href="https://i.stack.imgur.com/aNE4l.jpg" rel="nofollow noreferrer"><img src="https://i.stack.imgur.com/aNE4l.jpg" alt="enter image description here"></a></p>

<p>I installed the CH340 drivers from here <a href="https://sparks.gogo.co.nz/ch340.html" rel="nofollow noreferrer">https://sparks.gogo.co.nz/ch340.html</a> and I can see it in the device manager.
Connecting the Mega 2560 Pro Mini lights up the <code>L</code> and <code>On</code> LED but when pressing upload (testing with simple examples as Blink) I get the error and neither RX or TX lights up.</p>

<p>I have tried everything I can think of. What am I doing wrong?</p>

<p>I have confirmed that it is connected to the correct COM-port and I use these settings:</p>

<pre><code>Board: Arduino/Genuino Mega or Mega 2560
Processor: ATMega2560 (Mega 2560)
</code></pre>

<p>I have also tried many different USB-cables, short and long, and USB 2.0 and USB 3.0 ports. I use Windows 10 64-bit.</p>
 56461: <p>Try placing a 100nf capacitor on RST. That is usually required on an FTDI programmer.</p>

<p>See Edgar's post - <a href="https://arduino.stackexchange.com/users/47431/edgar">https://arduino.stackexchange.com/users/47431/edgar</a></p>
