text: user9072: I would like to find the proportion of each cell-type in bulk RNA-Seq transcriptomics data. I am looking for some guidance on the following:
  
  What are the state-of-the-art methods?
  What are their assumptions? (e.g. do they assume that cell-type expression signatures are available in advance?)
  
  
  user4766: I see a lot of people using xCell. There should also be papers systematically compare many different methods, which might interest you.
  
original_text: 9072: <p>I would like to find the proportion of each cell-type in bulk RNA-Seq transcriptomics data. I am looking for some guidance on the following:</p>
  <ul>
  <li>What are the state-of-the-art methods?</li>
  <li>What are their assumptions? (e.g. do they assume that cell-type expression signatures are available in advance?)</li>
  </ul>
   4766: <p>I see a lot of people using xCell. There should also be papers systematically compare many different methods, which might interest you.</p>
  