text: user1075: I download the Albacore wheel from Oxford Nanopore.
  I activated my conda environment that has Python 3 as the default python version.
  I tried to install Albacore with 
  pip3 install ont_albacore-2.1.10-cp36-cp36m-macosx_10_11_x86_64.whl
  
  but got the following error:
  ont_albacore-2.1.10-cp36-cp36m-macosx_10_11_x86_64.whl is not a supported wheel on this platform.
  You are using pip version 8.1.2, however version 9.0.1 is available.
  You should consider upgrading via the 'pip install --upgrade pip' command.`
  
  I then upgraded my pip with:
  pip install --upgrade pip
  Requirement already up-to-date: pip in /Users/.../anaconda3/envs/python3env/lib/python3.6/site-packages`
  
  So it seems that my pip was already up to date. I do not understand why it complains about my pip if I am using pip3 anyways. I tried to install Albacore again but I got the same message as before.
  Can anyone help me install Albacore on my Mac El Capitan laptop, please?
  Update based on Wouter's suggestion: 
  python -m pip install ont_albacore-2.1.10-cp36-cp36m-macosx_10_11_x86_64.whl
  Processing ./ont_albacore-2.1.10-cp36-cp36m-macosx_10_11_x86_64.whl
  Requirement already satisfied: python-dateutil in /Users/userName/anaconda3/lib/python3.6/site-packages (from ont-albacore==2.1.10)
  Requirement already satisfied: setuptools in /Users/userName/anaconda3/lib/python3.6/site-packages (from ont-albacore==2.1.10)
  Requirement already satisfied: h5py in /Users/userName/anaconda3/lib/python3.6/site-packages (from ont-albacore==2.1.10)
  Collecting progressbar33 (from ont-albacore==2.1.10)
  Requirement already satisfied: numpy>=1.12.1 in /Users/userName/anaconda3/lib/python3.6/site-packages (from ont-albacore==2.1.10)
  Collecting ont-fast5-api>=0.4.1 (from ont-albacore==2.1.10)
    Using cached ont_fast5_api-0.4.1-py2.py3-none-any.whl
  Requirement already satisfied: six>=1.5 in /Users/userName/anaconda3/lib/python3.6/site-packages (from python-dateutil->ont-albacore==2.1.10)
  Installing collected packages: progressbar33, ont-fast5-api, ont-albacore
  Successfully installed ont-albacore-2.1.10 ont-fast5-api-0.4.1 progressbar33-2.4
  
  At first sight, it looks like Albacore was successfully installed but if I run: read_fast5_basecaller.py --help
  I get: 
  Traceback (most recent call last):
    File "/Users/userName/anaconda3/bin/read_fast5_basecaller.py", line 69, in <module>
      from albacore.input_utils import list_input_files
    File "/Users/userName/anaconda3/lib/python3.6/site-packages/albacore/input_utils.py", line 7, in <module>
      from albacore import log_utils
    File "/Users/userName/anaconda3/lib/python3.6/site-packages/albacore/log_utils.py", line 5, in <module>
      from albacore.pipeline_core import get_debug_level
  ImportError: dlopen(/Users/userName/anaconda3/lib/python3.6/site-packages/albacore/pipeline_core.cpython-36m-darwin.so, 2): Library not loaded: /usr/local/opt/python3/Frameworks/Python.framework/Versions/3.6/Python
    Referenced from: /Users/userName/anaconda3/lib/python3.6/site-packages/albacore/pipeline_core.cpython-36m-darwin.so
    Reason: image not found
  
  Is there a library missing?
  
  user149: Not sure about conda as I don't use it, but I can highly recommend pipenv which is the python.org recommended package management system for python.  
  I have tested the following on my Mac and it worked like a dream  
  mkdir albacore && cd albacore
  mv ../ont_albacore-2.1.10-cp36-cp36m-macosx_10_11_x86_64.whl .
  
  # install pipenv if you don't have it
  brew install pipenv  # or pip3 install pipenv
  
  # the following will create a virtual environment and install albacore into it
  pipenv install ont_albacore-2.1.10-cp36-cp36m-macosx_10_11_x86_64.whl
  
  # activate the virtual environment
  pipenv shell
  
  read_fast5_basecaller.py -h
  
  And that should bring up the albacore help menu and you're ready to go.
  
original_text: 1075: <p>I download the <a href="https://mirror.oxfordnanoportal.com/software/analysis/ont_albacore-2.1.10-cp36-cp36m-macosx_10_11_x86_64.whl" rel="nofollow noreferrer">Albacore wheel</a> from Oxford Nanopore.</p>
  
  <p>I activated my conda environment that has Python 3 as the default python version.</p>
  
  <p>I tried to install Albacore with </p>
  
  <pre><code>pip3 install ont_albacore-2.1.10-cp36-cp36m-macosx_10_11_x86_64.whl
  </code></pre>
  
  <p>but got the following error:</p>
  
  <pre><code>ont_albacore-2.1.10-cp36-cp36m-macosx_10_11_x86_64.whl is not a supported wheel on this platform.
  You are using pip version 8.1.2, however version 9.0.1 is available.
  You should consider upgrading via the 'pip install --upgrade pip' command.`
  </code></pre>
  
  <p>I then upgraded my <code>pip</code> with:</p>
  
  <pre><code>pip install --upgrade pip
  Requirement already up-to-date: pip in /Users/.../anaconda3/envs/python3env/lib/python3.6/site-packages`
  </code></pre>
  
  <p>So it seems that my pip was already up to date. I do not understand why it complains about my <code>pip</code> if I am using <code>pip3</code> anyways. I tried to install Albacore again but I got the same message as before.</p>
  
  <p>Can anyone help me install Albacore on my Mac El Capitan laptop, please?</p>
  
  <p>Update based on Wouter's suggestion: </p>
  
  <pre><code>python -m pip install ont_albacore-2.1.10-cp36-cp36m-macosx_10_11_x86_64.whl
  Processing ./ont_albacore-2.1.10-cp36-cp36m-macosx_10_11_x86_64.whl
  Requirement already satisfied: python-dateutil in /Users/userName/anaconda3/lib/python3.6/site-packages (from ont-albacore==2.1.10)
  Requirement already satisfied: setuptools in /Users/userName/anaconda3/lib/python3.6/site-packages (from ont-albacore==2.1.10)
  Requirement already satisfied: h5py in /Users/userName/anaconda3/lib/python3.6/site-packages (from ont-albacore==2.1.10)
  Collecting progressbar33 (from ont-albacore==2.1.10)
  Requirement already satisfied: numpy&gt;=1.12.1 in /Users/userName/anaconda3/lib/python3.6/site-packages (from ont-albacore==2.1.10)
  Collecting ont-fast5-api&gt;=0.4.1 (from ont-albacore==2.1.10)
    Using cached ont_fast5_api-0.4.1-py2.py3-none-any.whl
  Requirement already satisfied: six&gt;=1.5 in /Users/userName/anaconda3/lib/python3.6/site-packages (from python-dateutil-&gt;ont-albacore==2.1.10)
  Installing collected packages: progressbar33, ont-fast5-api, ont-albacore
  Successfully installed ont-albacore-2.1.10 ont-fast5-api-0.4.1 progressbar33-2.4
  </code></pre>
  
  <p>At first sight, it looks like Albacore was successfully installed but if I run: <code>read_fast5_basecaller.py --help</code></p>
  
  <p>I get: </p>
  
  <pre><code>Traceback (most recent call last):
    File "/Users/userName/anaconda3/bin/read_fast5_basecaller.py", line 69, in &lt;module&gt;
      from albacore.input_utils import list_input_files
    File "/Users/userName/anaconda3/lib/python3.6/site-packages/albacore/input_utils.py", line 7, in &lt;module&gt;
      from albacore import log_utils
    File "/Users/userName/anaconda3/lib/python3.6/site-packages/albacore/log_utils.py", line 5, in &lt;module&gt;
      from albacore.pipeline_core import get_debug_level
  ImportError: dlopen(/Users/userName/anaconda3/lib/python3.6/site-packages/albacore/pipeline_core.cpython-36m-darwin.so, 2): Library not loaded: /usr/local/opt/python3/Frameworks/Python.framework/Versions/3.6/Python
    Referenced from: /Users/userName/anaconda3/lib/python3.6/site-packages/albacore/pipeline_core.cpython-36m-darwin.so
    Reason: image not found
  </code></pre>
  
  <p>Is there a library missing?</p>
   149: <p>Not sure about <code>conda</code> as I don't use it, but I can highly recommend <a href="https://pipenv.readthedocs.io/en/latest/" rel="nofollow noreferrer"><code>pipenv</code></a> which is the python.org recommended package management system for python.  </p>
  
  <p>I have tested the following on my Mac and it worked like a dream  </p>
  
  <pre><code>mkdir albacore &amp;&amp; cd albacore
  mv ../ont_albacore-2.1.10-cp36-cp36m-macosx_10_11_x86_64.whl .
  
  # install pipenv if you don't have it
  brew install pipenv  # or pip3 install pipenv
  
  # the following will create a virtual environment and install albacore into it
  pipenv install ont_albacore-2.1.10-cp36-cp36m-macosx_10_11_x86_64.whl
  
  # activate the virtual environment
  pipenv shell
  
  read_fast5_basecaller.py -h
  </code></pre>
  
  <p>And that should bring up the albacore help menu and you're ready to go.</p>
  