text: user8882: I was wondering if there was any R-package for receptor-ligand interaction similar to SingleCellSignal (https://github.com/SCA-IRCM/SingleCellSignalR_v1/blob/master/SingleCellSignalR/vignettes/UsersGuide.Rmd)
  +++ if there are vignettes and/or the graphs can be customized.
  +++ if it can be linked to Seurat
  Note: I have tried iTALK, but I keep getting an error that seems to be a common problem and have left a query. 
  Thanks
  
  user8777: Two nice tools for receptor-ligand interaction analysis are:
  
  CellPhoneDB by the Teichmann lab, although this is not an R package...
  NicheNet by the Saeys group
  
  Note that these tools are mainly meant for analysis of receptor-ligand interactions, although I think NicheNet also has some visualization options. CellPhoneDB needs to be run from a shell, but the results can easily be imported into R for visualization. You might check the papers on these 2 methods for some ideas of visualization. Combining Seurat's visualization options and ggplot2 should get you already pretty far.
  
original_text: 8882: <p>I was wondering if there was any R-package for receptor-ligand interaction similar to SingleCellSignal (<a href="https://github.com/SCA-IRCM/SingleCellSignalR_v1/blob/master/SingleCellSignalR/vignettes/UsersGuide.Rmd" rel="nofollow noreferrer">https://github.com/SCA-IRCM/SingleCellSignalR_v1/blob/master/SingleCellSignalR/vignettes/UsersGuide.Rmd</a>)</p>
  
  <p>+++ if there are vignettes and/or the graphs can be customized.</p>
  
  <p>+++ if it can be linked to Seurat</p>
  
  <p>Note: I have tried iTALK, but I keep getting an error that seems to be a common problem and have left a query. </p>
  
  <p>Thanks</p>
   8777: <p>Two nice tools for receptor-ligand interaction analysis are:</p>
  
  <ul>
  <li><a href="https://www.cellphonedb.org" rel="nofollow noreferrer">CellPhoneDB</a> by the Teichmann lab, although this is not an R package...</li>
  <li><a href="https://github.com/saeyslab/nichenetr" rel="nofollow noreferrer">NicheNet</a> by the Saeys group</li>
  </ul>
  
  <p>Note that these tools are mainly meant for analysis of receptor-ligand interactions, although I think NicheNet also has some visualization options. CellPhoneDB needs to be run from a shell, but the results can easily be imported into R for visualization. You might check the papers on these 2 methods for some ideas of visualization. Combining Seurat's visualization options and ggplot2 should get you already pretty far.</p>
  