text: user3524: Is there a way to calculate the area under a curve in a coverage graph?
  Thank you in advance.
  EDIT:
  I'd like to calculate the AUC per strand per gene in a coverage graph. I have two wig files (sense and antisense) generated from a single bam (RNA-seq) file (using the strand-coverage software).
  
  user73: Yes, just add up the coverage at each location; that's integration in a nutshell.
  Or, alternatively / equivalently, count the total number of reads within the region.
  
original_text: 3524: <p>Is there a way to calculate the area under a curve in a coverage graph?</p>
  
  <p>Thank you in advance.</p>
  
  <p>EDIT:</p>
  
  <p>I'd like to calculate the AUC per strand per gene in a coverage graph. I have two wig files (sense and antisense) generated from a single bam (RNA-seq) file (using the <a href="https://github.com/pmenzel/stranded-coverage" rel="nofollow noreferrer">strand-coverage</a> software).</p>
   73: <p>Yes, just add up the coverage at each location; that's integration in a nutshell.</p>
  
  <p>Or, alternatively / equivalently, count the total number of reads within the region.</p>
  