text: user1771: Reading Cusanovich et al. (2015) I encountered the sentence:
  
  We mixed pairs of cell lines (HEK293T or HL-60 versus GM12878), performed combinatorial cellular indexing, and sequenced the resulting libraries to saturation (65% duplicate rate).
  
  How is PCR duplication rate computed?
  
  Cusanovich, D. A. et al. Multiplex single-cell profiling of chromatin accessibility by combinatorial cellular indexing. Science 348, 910–914 (2015).
  
  
  user64: The answer is in the supplementary methods page 3.
  
  Finally, all fragments in the same library with duplicate start and
    end coordinates were removed using Picard
  
  
original_text: 1771: <p>Reading Cusanovich et al. (2015) I encountered the sentence:</p>
  
  <blockquote>
    <p>We mixed pairs of cell lines (HEK293T or HL-60 versus GM12878), performed combinatorial cellular indexing, and sequenced the resulting libraries to saturation (65% duplicate rate).</p>
  </blockquote>
  
  <p>How is PCR duplication rate computed?</p>
  
  <ol>
  <li>Cusanovich, D. A. et al. <a href="http://science.sciencemag.org/content/348/6237/910" rel="nofollow noreferrer">Multiplex single-cell profiling of chromatin accessibility by combinatorial cellular indexing.</a> Science 348, 910–914 (2015).</li>
  </ol>
   64: <p>The answer is in the <a href="http://science.sciencemag.org/content/sci/suppl/2015/05/06/science.aab1601.DC1/Cusanovich-SM.pdf" rel="nofollow noreferrer">supplementary methods page 3</a>.</p>
  
  <blockquote>
    <p>Finally, all fragments in the same library with duplicate start and
    end coordinates were removed using Picard</p>
  </blockquote>
  