text: user4600: I have a list of cell markers differentially expressed between 2 groups of cells, that I got with the FindMarkers command in Seurat. I want to enrich for those genes that are expressed in the cell membrane. Are there any specific tools/commands I can use to do that? Thanks! 
  
  user678: You can do functional enrichment analysis, for instance with gProfiler in R and see if your marker genes are enriched in any GO term related with the plasma membrane. 
  Alternatively, you can generate a list with genes whose product are located at the plasma membrane and perform Gene Set Enrichment Analysis, for instance with fgsea in R.
  
original_text: 4600: <p>I have a list of cell markers differentially expressed between 2 groups of cells, that I got with the FindMarkers command in Seurat. I want to enrich for those genes that are expressed in the cell membrane. Are there any specific tools/commands I can use to do that? Thanks! </p>
   678: <p>You can do functional enrichment analysis, for instance with <code>gProfiler</code> in R and see if your marker genes are enriched in any GO term related with the plasma membrane. </p>
  
  <p>Alternatively, you can generate a list with genes whose product are located at the plasma membrane and perform Gene Set Enrichment Analysis, for instance with <code>fgsea</code> in R.</p>
  