text: user4307: I was wondering if somebody here has experience with installing scvi-tools on a Mac with M1 chip. I tried the following command:
  conda install scvi-tools -c conda-forge
  
  But got the following error:
  Collecting package metadata (current_repodata.json): failed
  CondaSSLError: OpenSSL appears to be unavailable on this machine. OpenSSL is required to
  download and install packages.
  Exception: HTTPSConnectionPool(host='conda.anaconda.org', port=443): Max retries exceeded with url: /conda-forge/osx-64/current_repodata.json (Caused by SSLError("Can't connect to HTTPS URL because the SSL module is not available."))
  
  Then I tried to install OpenSSL with following command:
  conda install -c anaconda openssl 
  
  and I got the exact same error as the conda install scvi-tools -c conda-forge command.
  I do not understand why collection of metadata is failing for openssl. Any inputs would be highly helpful.
  Thanks!
  
  user3061: Did you try:
  pip install scvi-tools
  
  ?
  
original_text: 4307: <p>I was wondering if somebody here has experience with installing scvi-tools on a Mac with M1 chip. I tried the following command:</p>
  <pre><code>conda install scvi-tools -c conda-forge
  </code></pre>
  <p>But got the following error:</p>
  <pre><code>Collecting package metadata (current_repodata.json): failed
  CondaSSLError: OpenSSL appears to be unavailable on this machine. OpenSSL is required to
  download and install packages.
  Exception: HTTPSConnectionPool(host='conda.anaconda.org', port=443): Max retries exceeded with url: /conda-forge/osx-64/current_repodata.json (Caused by SSLError(&quot;Can't connect to HTTPS URL because the SSL module is not available.&quot;))
  </code></pre>
  <p>Then I tried to install OpenSSL with following command:</p>
  <pre><code>conda install -c anaconda openssl 
  </code></pre>
  <p>and I got the exact same error as the conda install scvi-tools -c conda-forge command.</p>
  <p>I do not understand why collection of metadata is failing for openssl. Any inputs would be highly helpful.
  Thanks!</p>
   3061: <p>Did you try:</p>
  <pre><code>pip install scvi-tools
  </code></pre>
  <p>?</p>
  