text: user9: Is there a best practices for mapping Oxford Nanopore files to a reference?
  Is there a tool that can take a tarball of fast5 files and map them directly or do they need to be converted to fastq first?
  
  user73: Fast5 files need to be converted to fastq first prior to mapping. There are currently no tools available to map the entire raw signal directly to a reference, although a few tools are available for identifying short sequences within the raw signal.
  
original_text: 9: <p>Is there a best practices for mapping Oxford Nanopore files to a reference?</p>
  
  <p>Is there a tool that can take a tarball of fast5 files and map them directly or do they need to be converted to fastq first?</p>
   73: <p>Fast5 files need to be converted to fastq first prior to mapping. There are currently no tools available to map the entire raw signal directly to a reference, although a few tools are available for identifying short sequences within the raw signal.</p>
  