text: user1201: I am interested in finding a database that takes a gene or protein name as input (possibly with the option to specify transcript) and gives information about the protein's functional domains in terms of either specific residue ranges, genomic coordinates, etc. Ideally, the database would include 3D conformational information as well as the functional domains. Does such a database exist? It seems that this information can be inferred for a given protein using various publications and references but I have yet to find a single collection containing these data all in one place.
  
  user298: EnsEMBL also has this. Search for your gene of interest, choose your transcript, go to the page of its protein product(s), and select "Domains & Features" from the right-hand menu (using human p53 as an example):
  Domain source       Start End  Description                                            Accession InterPro  
  PANTHER             3     331  -                                                      PTHR11447:SF6-         
  Pfam                5     29   p53 transactivation domain                             PF08563   IPR013872 
  PANTHER             3     331  p53 tumour suppressor family                           PTHR11447 IPR002117 
  PRINTS              116   142  p53 tumour suppressor family                           PR00386   IPR002117 
  PRINTS              158   179  p53 tumour suppressor family                           PR00386   IPR002117 
  PRINTS              213   234  p53 tumour suppressor family                           PR00386   IPR002117 
  PRINTS              236   258  p53 tumour suppressor family                           PR00386   IPR002117 
  Prosite_patterns    237   249  p53 tumour suppressor family                           PS00348   IPR002117 
  PRINTS              264   286  p53 tumour suppressor family                           PR00386   IPR002117 
  Pfam                95    288  p53 DNA-binding domain                                 PF00870   IPR011615 
  Superfamily         97    287  p53-like transcription factor DNA-binding              SSF49417  IPR008967 
  Gene3D              94    297  p53/RUNT-type transcription factor DNA-binding domain  2.60.40.720IPR012346 
  
  
  user306: Some of this information (at least some domains, active sites, etc) is available from UniProt.
  If you want to download their whole database, you can search without specifying any terms and then click the Download button.
  
original_text: 1201: <p>I am interested in finding a database that takes a gene or protein name as input (possibly with the option to specify transcript) and gives information about the protein's functional domains in terms of either specific residue ranges, genomic coordinates, etc. Ideally, the database would include 3D conformational information as well as the functional domains. Does such a database exist? It seems that this information can be inferred for a given protein using various publications and references but I have yet to find a single collection containing these data all in one place.</p>
   298: <p><a href="http://www.ensembl.org" rel="nofollow noreferrer">EnsEMBL</a> also has this. Search for your gene of interest, choose your transcript, go to the page of its protein product(s), and select "Domains &amp; Features" from the right-hand menu (using human p53 as an example):</p>
  
  <pre><code>Domain source       Start End  Description                                            Accession InterPro  
  PANTHER             3     331  -                                                      PTHR11447:SF6-         
  Pfam                5     29   p53 transactivation domain                             PF08563   IPR013872 
  PANTHER             3     331  p53 tumour suppressor family                           PTHR11447 IPR002117 
  PRINTS              116   142  p53 tumour suppressor family                           PR00386   IPR002117 
  PRINTS              158   179  p53 tumour suppressor family                           PR00386   IPR002117 
  PRINTS              213   234  p53 tumour suppressor family                           PR00386   IPR002117 
  PRINTS              236   258  p53 tumour suppressor family                           PR00386   IPR002117 
  Prosite_patterns    237   249  p53 tumour suppressor family                           PS00348   IPR002117 
  PRINTS              264   286  p53 tumour suppressor family                           PR00386   IPR002117 
  Pfam                95    288  p53 DNA-binding domain                                 PF00870   IPR011615 
  Superfamily         97    287  p53-like transcription factor DNA-binding              SSF49417  IPR008967 
  Gene3D              94    297  p53/RUNT-type transcription factor DNA-binding domain  2.60.40.720IPR012346 
  </code></pre>
   306: <p>Some of this information (at least some domains, active sites, etc) is available from <a href="http://www.uniprot.org/" rel="nofollow noreferrer">UniProt</a>.</p>
  
  <p>If you want to download their whole database, you can search without specifying any terms and then click the Download button.</p>
  