premise: Two men playing a guitar game on a tv. hypothesis: The two men are professional Rock Band players, getting ready for a national Rock Band competition.
neutral: There is no possible way that a determination could be made that the two men are professional Rock Band players, getting ready for a national Rock Band competition based on the sentence stating they are playing a guitar game on tv. For all we know they are just two guys that live in their mother's basement just learning the game.