( some spoiler ) it take some 19 year for bruce campbell to finally put his masterpiece man with the scream brain on the screen . but campbell have to alter his story by have it and due to financial problem and take place in sofia bulgaria not where he initially want it to be film in los angeles california . in the film burce campbell play u pharmaceutical tycoon willian cole who travel together with his spoiled rotten wife jackie and antoinette byron and to the former communist republic of bulgaria . it there that william want to help finance bulgaria almost non existent mass transportation system . it poor william misfortune to get involve with both gypsy woman tatoya and tamara gorski and and her ex boyfriend yegor and valdimir kolev and an ex kgb taxi driver . the two and william and yegor and will unwittingly end up shear their brain and inside william skull and because of tatoya jealousy and vindictiveness . after tatoya murder both william and yegor their body be deliver to mad scientist dr. ivan ivanowitch ivanov and stacy keach and by his loyal assistant pavel and ted raimi and to have their brain experiment with . dr. ivanov have this theory in that two head be well then one . and now with the material and william and yegor and available to him dr. ivanov at last be finally go to prove it . what dr. ivanov be go to sadly find out be that by fuse the two head and or brain and together their brain wave will overlap and cause them to not only malfunction but turn against each other . william with yegor right lobe fuse into his damage brain be out to find tatoya and make her pay for the damage she cause both him and yegor . yegor for his part be stick in william head who like and dislike and in both food and drink and be totally opposite to his own . this cause a lot of tension and hostility between the two brain in them fight for control of william body . thing get even more screw up when jackie find out that tatoya murder her husband william confront her in the dangerous and high crime section of bravoda call gypsy town and end up be murder herself . bring back to dr. ivanov by his assistant pavel it determine and with no body available and to plant jackie brain inside of an experimental robot that pavel be work on . the operation be a rouse success but the only drawback be that jackie and with her brain inside the robot and have to have her brain recharge every few hour . or and like a real brain lacking oxygen and she will die together with the robot battery . combination 1930 like screw ball comedy and horror flick with both william and yegor turn the bulgarian town of bravoda upside down in try to find tatoya and make her pay and with her life and for the sad state of existence she put them both into . spoiler alert it dr. ivanov who in fact save the day by discover how to keep the two brain from fight and and thus cooperate and with each other . this be do by him instead of fuse the brain together dr. ivanov keep them independent by implant a neutralizing cell wall in between the two uncooperative glob of gray matter .