boris karloff makeup isn not frightening and but his eye and facial expression keep you on edge . boris karloff be work on a cure for cancer by freeze and dr kravaal ( boris karloff ) place his die patient in an underground ice chamber carve out from a surround glacier . one of his patient die and boris be in fear of be arrest . karloff use a powerful drug which put boris and his captor in an unconscious rest . ten year after the disappearance of dr. kravaal and they discover the ice chamber contain the frozen body . the story progreses with karloff go out of control experiment with his prisoner and use them a his guinea pig until he obtain the complete formula . all you can say about this picture be that boris be try to cure cancer the best way that he could in 1940 .