a doctor research frozen therapy seek out boris karloff and the therapy originator . boris have be miss from his island laboratory for ten year . after ignore request to stay off the island by local and the doctor and his beautiful nurse discover boris frozen in secret cave beneath the lab . boris have be freeze along with a host of villager . through flashback it be learn these others come to arrest boris for murder ten year earlier and they all wind up be gas and frozen . this be the proof karloff need to vindicate his research . he set out to duplicate his accidental result and his method become increasingly machiavellian . ultimately he be his own undoing . this movie be hard to catagorize . the film maker try to add shock to an interesting scifi story . the film succeed in spite of the effort to punch it up . the acting be uneven but overall this be a top notch b effort . the science be very plausible and a rarity in old laboratory film . see it and be pleasantly surprise .