<s>[INST] I have a small pea sized lump at the bottom of my thumb near my wrist. On my right palm. It is sometimes tender to the touch. I discovered it when I started to get pain in my palm and it was uncomfatable every time I tied my shoes or used my hand. It radiated into my wrist. I started using ibuprofen and it helped to relieve some symptoms. [/INST] It can be ganglion which is basically a swelling from the joint or some lipoma which is fat containing swelling. The Painkillers are good option for it </s>