<s>[INST] daughter has high functioning asperer she has been treated by several doctor she suffers from severe depression and anxiety she was on Prozac for several years then starting cutting they took her off she refuses to leave her room my insurance cut her benefits I am at my wits end every year she get worse.she is 16 [/INST] Greetings !I am sorry to learn about your daughter's condition.Well if she has responded to prozac before and she had previously  not developed resistance or increased tolerance against the drug then she should be again placed on prozac since this is a tried and tested drug with good results in the past.However if prozac had become ineffective due to prolonged usage then she needs to be placed on a new anti depressant drug such as escitalopram at dose of 5 mg / day to begin with and the dose to be raised to 10 mg / day after 2-3 weeks if the need arises.This drug escitalopram is a better ssri anti depressant as compared to prozac and is also faster acting and associated with relatively fewer side effects.So i have laid down two options in the form of re-introduction of prozac or use of new drug like escitalopram, either should be able to manage her depression and anxiety.I hope this helps.Regards </s>