<s>[INST] Hello, I am a black female who is 54 years old. My symptoms are breast heaviness, ankle swelling, a smelly discharge from my vagina and a bloated belly. I am also a controlled diabetic 2, active and I eat healthy. Never use alcohol nor cigarettes, and I still have a normal period every month. Is it possible my meds are interfering w/ me? I take insulin, janumet, metformin, and linzess for chronic constipation. I had a period over 2 wks. ago, yet, my breasts are still full and I have the bloating. I truly hope this is a benign condition. [/INST] Hello, Metformin can cause abdominal bloating; flatulence etc as side effects. However, none of the drugs mentioned is known to cause breast heaviness, ankle swelling. Insulin though can cause weight gain. Hope I have answered your query. Let me know if I can assist you further. Take care Regards, Dr Tushar Kanti Biswas, Internal Medicine Specialist </s>