<s>[INST] My brother has been diagnosed with a GI Cancer and will begin chemo treatments next week. I was researching the drugs and have found that two have a major drug reaction---major being described as risk outweighs the benefit! The drugs are Adrucil and Leucovorin; what would be the reason for using the two together? Do I keep quiet or ask him? [/INST] Dear, I think you have wrongly been informed about the side effects of these drugs. They are safe and can be given conveniently. i will say the reverse benifit overweighs the risk. At least with first 4 or 5 cycles of chemotherapy there will absolutely be no problem. Dr. Ticku </s>