<s>[INST] I have taken a blood test to see if I am a match to donate a kidney to my neighbor. I am. I have a lot of questions. -What is the most painful part of the transplant. I once had my gull bladder removed and the stiches were pretty painful when taken out. Will the incisions be like the ones in gull bladder surgery? -I am a avid runner, will I be able to continue running after my recovery? -Do donors experience weight gain or loss after surgery? - I understand after you donate a kidney you will likely develop hyper tension is that true? [/INST] Thank you for your query. The incision to remove a kidney is a large one made on the back, radiating to the side. The incision pain will be similar to the one with your cholecystectomy . To remove the sutures should not be painful. Obviously for the first couple of days post operatively , pain medication will be administered . Although your kidneys do regulate your blood pressure having one kidney does not meen you will develop hypertension,also having one kidney has no effect on your weight. Running is possible with one kidney but caution will have to be taken, as ultra long distance running may cause mechanical trauma to the kidney. I trust this is helpful. </s>