<s>[INST] I AM A CKD PATIENT NOW ON CAPD. NEED TRANSPLANT. MY KIDNEY'S NOT BEEN DONE ANY BIOPSY BUT MY DR. IN KUWAIT IS TELLING KIDNEY FAILED DUE TO ANTI GBM ANTIBODY. I HAVE SKIN DISEASE FOR 35 YRS AND I THINK THERE IS RELATION BETWEEN THIS SKIN DISEASE AND KIDNEY DISEASE. IF I GO FOR TRANSPLANT, DOES THIS PROBLEM AFFECT MY NEW TRANSPLANTED KIDNEY? [/INST] Hi,A lot of research is going on on the topic of anti glomerular basement membrane (anti GBM) antibody disease recurrence after transplantation. Anti-glomerular basement membrane (GBM) antibody disease may progress to end-stage renal failure, requiring either dialysis or renal transplantation. There are only six reported cases of symptomatic recurrent anti-GBM disease in the literature. The incidence of recurrent linear Immunoglobulin G (IgG) staining in the transplant may be as high as 50 percent. However, most patients remain asymptomatic. You may discuss this point with your doctor. </s>