<s>[INST] I m having frequent foot and leg and hand cramps almost daily for a couple of weeks. I ve been on prednisone for asthmatic bronchitis and double pneumonia since Dec. 8. What could be the cause, please? I suspect my potassium is low. A possibility? [/INST] Hi,Yes. Commonly low potassium, dehydration, low calcium and also low protein level can cause leg and hand cramps. Prednisone if you are using tablet can cause fluid retention and also vary calcium metabolism. So Get checked to these serum electrolyte levels and if abnormal replenish them. Use plenty of fluids.For asthmatic bronchitis prefer inhalers than oral tablets.Hope this helps you.Regards </s>