<s>[INST] My sister aged 45 years has abnormal behaviour.Wants to be alone, doesn t like mass of people . uses locks at room even rooms and windows are closed . uses bad words even for her children. Does work opposite to what is said to her.please suggest what to do... [/INST] Hello thanks for asking from HCMThe symptoms like social withdrawal (living alone), not liking people, bad words and scolding children could occur in depression though detailed evaluation is needed to make a diagnosis. She is also showing aggressive behaviour and this could be due to atypical features of depression. I would advise you to consult a psychiatrist for her treatment. For depressive symptoms SSRI medicines like Sertraline, Paroxetine etc prove useful. For aggression medicines like Mood stabilisers as Sodium Valproate, Carbamazapine etc can help in improvement. Consult a psychiatrist for proper prescription of these drugs.Advise her to do relaxation exercises, yoga to relax herself. Cognitive therapy also have excellent effects in depression.Thanks, hope this helps you. </s>