<s>[INST] hello, I am on clomid 50 mg and this is the second cycle.  I responded well the first cycle and now this cycle there are two follicles in my right ovary but growing very slowly.  on day 10 it was 1.2 and day 13 it was 1.3 and day 15 i was 1.6 so my doctor has said to take 2 clomid 100 mg from today (day 15) and she will she me next week.  I wanted a second opinion is it safe to take at this stage of my cycle and will i have any side effects as it will be 2X the dose? [/INST] Hi , How are you doing ?I don't agree with this management. Clomid is Clomiphene is hormone which causes increase in hormone which makes the follicular  growth better. But it's main side effect is it will reduce the inner lining of the uterus. If this is reduced , the pregnancy chances is reduced, as this lining is needed for the embryo/ baby to get good attachment to uterus. So the better option is to have dose of hormone injections to increase the follicular size.  It will be safe to increase dose of Clomid in next cycle. But by just increasing dose of tablet , problem will not be solved. Better to take hormone injection from the beginning & you will get a much better follicular response. Hope I have clarified your queries All the bestDr.Balakrishnan </s>