<s>[INST] My sister has pain in her leg, just below the knee, anterior/medial location, for a week. Now she is c/o pain in that leg if she takes a deep breath or coughs. Went to doctor Wednesday, blood work and x-ray done, no frx. Doctor said no clot but didn t do venous Doppler. She had greatly increased her activity by doing painting and trying to jog the past week. [/INST] For pain in leg here first you need to check either it's at knee level or at calf muscle level.  If it's close to calf muscle level then check with squizing calf muscle belly and if it pains then it can be related to vascularity it issue of lower limb and dopler test is needed.  But if this is  negative then it may be only over use injury. Now if pain is only at knee level then again need to check with few physical test.  As a conservative treatment management you can use hot and cold pack at pain full area with rest for few days and avoiding any activity which pains. But if it does not give pain relief then visit a good physio and orthopedic  who can check with physical test and evaluate the problem as well guide you with treatment and exercise program. Follow the advice and I am sure it will be useful.  Take care </s>