<s>[INST] My wife is suffering from CRF for at least 3 years. Her present creatine leve is 7.5, Blood Urea 169, Hb% 5.9, Sugar (fasting) 89 and BP varying between 130/80 and 160/90. Her other parameters, like Lipid profile, are more or less normal. Now, I wish to have Kidney transplantation for my wife, instead of giving Dialysis at regular intervals. I am ready to donate my kidney. My blood group is O+ and my wife s is A+. How to proceed in this case ? Wish to know the protocol in this case. [/INST] you can donate your kidney to your wife. however, you need to be seen by nephrologist and urologist and a huge load of investigations need to be done before you are deemed fit to donate your kidney </s>