There's some chance that you were just unlucky and it might be a very small chance and that's why you want to do this with a good number of people. And as we forward our statistics understandings, we will better understand at what threshold levels do we think the probability is high or low enough for us to really feel good about our findings. But let's say that you do see, let's say that you do see an improvement. You need to think about is that improvement, could that have happened due to random chance or is it very unlikely that that happened due purely to random chance? And if it was very unlikely that it happened due purely to random chance, then you would feel pretty good, and other people, when you publish the results, would feel pretty good about your medicine. Now, even then, you know, science is not done. No one will say that they're 100% sure that your medicine is good.